CA1089451A - Imidazole derivatives - Google Patents

Imidazole derivatives

Info

Publication number
CA1089451A
CA1089451A CA284,193A CA284193A CA1089451A CA 1089451 A CA1089451 A CA 1089451A CA 284193 A CA284193 A CA 284193A CA 1089451 A CA1089451 A CA 1089451A
Authority
CA
Canada
Prior art keywords
alkyl
general formula
conh
compounds
imidazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA284,193A
Other languages
English (en)
French (fr)
Inventor
Ulf Fischer
Pierre-Charles Wyss
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Application granted granted Critical
Publication of CA1089451A publication Critical patent/CA1089451A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052Imidazole radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
CA284,193A 1976-08-06 1977-08-05 Imidazole derivatives Expired CA1089451A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ATA5859/76 1976-08-06
AT585976A AT350735B (de) 1976-08-06 1976-08-06 Verfahren zur herstellung von neuen ribo- furanosyl-imidazolderivaten

Publications (1)

Publication Number Publication Date
CA1089451A true CA1089451A (en) 1980-11-11

Family

ID=3580308

Family Applications (1)

Application Number Title Priority Date Filing Date
CA284,193A Expired CA1089451A (en) 1976-08-06 1977-08-05 Imidazole derivatives

Country Status (10)

Country Link
US (1) US4115641A (online.php)
JP (1) JPS5321165A (online.php)
AT (1) AT350735B (online.php)
BE (1) BE857512A (online.php)
CA (1) CA1089451A (online.php)
DE (1) DE2735458A1 (online.php)
FR (1) FR2360604A1 (online.php)
GB (1) GB1581467A (online.php)
NL (1) NL7708696A (online.php)
ZA (1) ZA774612B (online.php)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0004261B1 (de) * 1978-02-01 1982-04-28 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Neue Imidazolderivate, Verfahren zu deren Herstellung und Arzneimittel diese enthaltend
JPS55116582U (online.php) * 1979-02-13 1980-08-16
IL99125A0 (en) * 1990-08-10 1992-07-15 Gensia Pharma Derivatives of imidazole analog of aica riboside and their use
IL99124A (en) * 1990-08-10 1998-02-22 Gensia Pharma Substituted imidazole analogs of aica riboside
JP2008534601A (ja) 2005-03-28 2008-08-28 ペリコー セラピューティクス, インコーポレイテッド 患者における副作用を予防または減少するための方法、組成物および処方物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2034785A1 (de) * 1970-07-14 1972-01-20 Boehnnger Mannheim GmbH, 6800 Mann heim Waldhof Adenosin 5 carbonsäurederivate
DE2105560A1 (de) * 1971-02-06 1972-09-07 Boehringer Mannheim Gmbh, 6800 Mannheim Purinribonucleosid-Derivate und Verfahren zur Herstellung derselben
US3897415A (en) * 1971-06-01 1975-07-29 Icn Pharmaceuticals 5-Substituted 1,2,4-triazole-3-carboxamido nucleosides and analogs thereof
CH563405A5 (online.php) * 1971-09-10 1975-06-30 Duschinsky Robert Dr Schweiz I
US3864483A (en) * 1972-03-22 1975-02-04 Abbott Lab Adenosine-5{40 -carboxylic acid amides
US3855205A (en) * 1972-10-03 1974-12-17 Abbott Lab Process for preparing adenosine-5{40 -carboxylates
DE2342479A1 (de) * 1973-08-23 1975-03-13 Merck Patent Gmbh Ribonucleosid-5'-nitrate und verfahren zu ihrer herstellung
LU72078A1 (online.php) * 1975-03-18 1977-01-31
CH658188A5 (de) * 1984-03-23 1986-10-31 Ciba Geigy Ag Lagerstabile schnellzerfallende pharmazeutische presslinge.

Also Published As

Publication number Publication date
US4115641A (en) 1978-09-19
ZA774612B (en) 1978-06-28
NL7708696A (nl) 1978-02-08
FR2360604A1 (fr) 1978-03-03
DE2735458A1 (de) 1978-02-09
JPS5321165A (en) 1978-02-27
AT350735B (de) 1979-06-11
ATA585976A (de) 1978-11-15
BE857512A (fr) 1978-02-06
GB1581467A (en) 1980-12-17
FR2360604B1 (online.php) 1979-07-13

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Legal Events

Date Code Title Description
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