CA1083140A - Estramustine phosphate alcohol complexes, their preparation, and their use as intermediates in purification of said compound and salts thereof - Google Patents

Estramustine phosphate alcohol complexes, their preparation, and their use as intermediates in purification of said compound and salts thereof

Info

Publication number
CA1083140A
CA1083140A CA273,564A CA273564A CA1083140A CA 1083140 A CA1083140 A CA 1083140A CA 273564 A CA273564 A CA 273564A CA 1083140 A CA1083140 A CA 1083140A
Authority
CA
Canada
Prior art keywords
estramustine phosphate
salt
estramustine
alcohol
phosphate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA273,564A
Other languages
English (en)
French (fr)
Inventor
Anders R. Stamvik
Sten K. Kristensson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo AB
Original Assignee
Leo AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo AB filed Critical Leo AB
Application granted granted Critical
Publication of CA1083140A publication Critical patent/CA1083140A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA273,564A 1976-03-10 1977-03-09 Estramustine phosphate alcohol complexes, their preparation, and their use as intermediates in purification of said compound and salts thereof Expired CA1083140A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9451/76 1976-03-10
GB9451/76A GB1523035A (en) 1976-03-10 1976-03-10 Derivatives of estradiol - 17 - dihydrogen phosphates

Publications (1)

Publication Number Publication Date
CA1083140A true CA1083140A (en) 1980-08-05

Family

ID=9872205

Family Applications (1)

Application Number Title Priority Date Filing Date
CA273,564A Expired CA1083140A (en) 1976-03-10 1977-03-09 Estramustine phosphate alcohol complexes, their preparation, and their use as intermediates in purification of said compound and salts thereof

Country Status (17)

Country Link
US (1) US4115414A (US07993877-20110809-P00003.png)
JP (2) JPS52108963A (US07993877-20110809-P00003.png)
AT (1) AT355737B (US07993877-20110809-P00003.png)
BE (1) BE852271A (US07993877-20110809-P00003.png)
CA (1) CA1083140A (US07993877-20110809-P00003.png)
CH (1) CH633813A5 (US07993877-20110809-P00003.png)
DE (1) DE2710293C2 (US07993877-20110809-P00003.png)
DK (1) DK156007C (US07993877-20110809-P00003.png)
FR (1) FR2343752A1 (US07993877-20110809-P00003.png)
GB (1) GB1523035A (US07993877-20110809-P00003.png)
IE (1) IE45024B1 (US07993877-20110809-P00003.png)
IL (1) IL51592A (US07993877-20110809-P00003.png)
IT (1) IT1075668B (US07993877-20110809-P00003.png)
LU (1) LU76927A1 (US07993877-20110809-P00003.png)
MX (1) MX5242E (US07993877-20110809-P00003.png)
NL (1) NL7702608A (US07993877-20110809-P00003.png)
SE (1) SE428928B (US07993877-20110809-P00003.png)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2554005B2 (ja) * 1993-02-18 1996-11-13 株式会社パーマケム・アジア エストラムスチンフォスフェート又はその塩類の精製方法
US6040255A (en) * 1996-06-25 2000-03-21 Kimberly-Clark Worldwide, Inc. Photostabilization package usable in nonwoven fabrics and nonwoven fabrics containing same
US20040072889A1 (en) * 1997-04-21 2004-04-15 Pharmacia Corporation Method of using a COX-2 inhibitor and an alkylating-type antineoplastic agent as a combination therapy in the treatment of neoplasia
GB9921958D0 (en) * 1999-09-16 1999-11-17 Pharmacia & Upjohn Spa Formulations for parenteral use of estramustine phosphate and sulfoalkylether-cyclodextrins

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299104A (en) 1963-04-09 1967-01-17 Leo Ab Certain steroid nu-bis-(haloethyl)-carbamates
GB1458372A (en) * 1973-03-05 1976-12-15 Leo Ab Steroid carbamates and allophanates

Also Published As

Publication number Publication date
JPS5526160B2 (US07993877-20110809-P00003.png) 1980-07-11
DK103577A (da) 1977-09-11
LU76927A1 (US07993877-20110809-P00003.png) 1978-10-18
GB1523035A (en) 1978-08-31
IL51592A0 (en) 1977-05-31
DE2710293A1 (de) 1977-09-15
JPS5589300A (en) 1980-07-05
BE852271A (fr) 1977-09-09
AT355737B (de) 1980-03-25
US4115414A (en) 1978-09-19
MX5242E (es) 1983-05-16
DK156007C (da) 1989-11-06
DK156007B (da) 1989-06-12
ATA157777A (de) 1979-08-15
IT1075668B (it) 1985-04-22
SE7702613L (sv) 1977-09-11
FR2343752B1 (US07993877-20110809-P00003.png) 1978-10-20
IE45024B1 (en) 1982-06-02
SE428928B (sv) 1983-08-01
IE45024L (en) 1977-09-10
FR2343752A1 (fr) 1977-10-07
JPS5755720B2 (US07993877-20110809-P00003.png) 1982-11-25
NL7702608A (nl) 1977-09-13
CH633813A5 (de) 1982-12-31
DE2710293C2 (de) 1986-06-12
IL51592A (en) 1980-09-16
JPS52108963A (en) 1977-09-12

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Legal Events

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