CA1072086A - Phenylindolines and process for their production - Google Patents

Phenylindolines and process for their production

Info

Publication number
CA1072086A
CA1072086A CA255,475A CA255475A CA1072086A CA 1072086 A CA1072086 A CA 1072086A CA 255475 A CA255475 A CA 255475A CA 1072086 A CA1072086 A CA 1072086A
Authority
CA
Canada
Prior art keywords
formula
process according
lower alkyl
phenyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA255,475A
Other languages
English (en)
French (fr)
Inventor
Vaclav Musil
Lise A. Hughes
Rudolf Kubela
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Delmar Chemicals Inc
Original Assignee
Delmar Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delmar Chemicals Inc filed Critical Delmar Chemicals Inc
Application granted granted Critical
Publication of CA1072086A publication Critical patent/CA1072086A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA255,475A 1975-06-23 1976-06-23 Phenylindolines and process for their production Expired CA1072086A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/589,402 US4080330A (en) 1975-06-23 1975-06-23 Phenylindolines and process for their production

Publications (1)

Publication Number Publication Date
CA1072086A true CA1072086A (en) 1980-02-19

Family

ID=24357858

Family Applications (1)

Application Number Title Priority Date Filing Date
CA255,475A Expired CA1072086A (en) 1975-06-23 1976-06-23 Phenylindolines and process for their production

Country Status (6)

Country Link
US (3) US4080330A (enExample)
JP (1) JPS5212162A (enExample)
CA (1) CA1072086A (enExample)
DE (1) DE2628189A1 (enExample)
FR (1) FR2315270A1 (enExample)
GB (1) GB1550230A (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4428881A (en) 1977-12-23 1984-01-31 Gulf Oil Corporation Control of unwanted vegetation with N-carbamylindolines
DE3022648A1 (de) * 1979-06-29 1981-01-15 Sandoz Ag Neue organische verbindungen, ihre herstellung und pharmazeutischen praeparate, welche diese verbindungen enthalten
DE3114351A1 (de) * 1981-04-09 1982-11-04 Hoechst Ag, 6000 Frankfurt "oxindol-derivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel mit neuroanaboler wirkung"
AU7707994A (en) * 1993-09-30 1995-04-18 Tokyo Tanabe Company Limited Indoline derivative and 5-ht3 receptor antagonist containing the same as active ingredient
WO1996025396A1 (en) * 1995-02-17 1996-08-22 Tokyo Tanabe Company Limited Process for producing indoline compounds and intermediates for the production of the same
AU718434B2 (en) * 1995-02-17 2000-04-13 Mitsubishi-Tokyo Pharmaceuticals, Inc. Process for producing indoline compounds and intermediates for the production of the same
FR2744452B1 (fr) * 1996-02-06 1998-03-06 Cird Galderma Composes biaryles heterocycliques, compositions pharmaceutiques et cosmetiques les contenant et utilisations
FR2805753B1 (fr) 2000-03-06 2002-05-17 Salomon Sa Ensemble semelle cable
CA2627426A1 (en) * 2005-11-11 2007-05-18 Markus Boehringer Carbocyclic fused cyclic amines as inhibitors of the coagulation factor xa
GB201106817D0 (en) * 2011-04-21 2011-06-01 Astex Therapeutics Ltd New compound
GB201218864D0 (en) 2012-10-19 2012-12-05 Astex Therapeutics Ltd Bicyclic heterocycle compounds and their uses in therapy
GB201218862D0 (en) 2012-10-19 2012-12-05 Astex Therapeutics Ltd Bicyclic heterocycle compounds and their uses in therapy
GB201218850D0 (en) 2012-10-19 2012-12-05 Astex Therapeutics Ltd Bicyclic heterocycle compounds and their uses in therapy
US9980973B2 (en) 2012-10-19 2018-05-29 Astex Therapeutics Limited Bicyclic heterocycle compounds and their uses in therapy
TWI649319B (zh) * 2013-12-20 2019-02-01 英商阿斯迪克治療公司 雙環雜環化合物及其治療用途
AR128391A1 (es) * 2022-01-31 2024-04-24 Rhizen Pharmaceuticals Ag Inhibidores pol theta

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3184466A (en) * 1965-05-18 Beta amino butyrylxnbqlines
JPS433614Y1 (enExample) * 1964-01-29 1968-02-15
US3558653A (en) * 1968-05-20 1971-01-26 Searle & Co Dialkylaminoalkyl-indolines
GB1237008A (en) * 1968-12-18 1971-06-30 Pfizer Ltd Novel indoline derivatives
US3732236A (en) * 1971-04-12 1973-05-08 Mead Johnson & Co 2-phenyl-indoline amidines
US3989714A (en) * 1972-09-21 1976-11-02 Warner-Lambert Company 3-Phenylhydroindoles
US3890348A (en) * 1973-03-26 1975-06-17 Sandoz Ag Indole-1 and indoline-1-carboxamides and thiocarboxamides

Also Published As

Publication number Publication date
JPS5212162A (en) 1977-01-29
DE2628189A1 (de) 1977-01-20
US4080330A (en) 1978-03-21
FR2315270B1 (enExample) 1979-09-21
US4153789A (en) 1979-05-08
FR2315270A1 (fr) 1977-01-21
US4138494A (en) 1979-02-06
GB1550230A (en) 1979-08-08

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Legal Events

Date Code Title Description
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