CA1067490A - Prostanoic acid derivatives - Google Patents

Prostanoic acid derivatives

Info

Publication number
CA1067490A
CA1067490A CA231,547A CA231547A CA1067490A CA 1067490 A CA1067490 A CA 1067490A CA 231547 A CA231547 A CA 231547A CA 1067490 A CA1067490 A CA 1067490A
Authority
CA
Canada
Prior art keywords
radical
alpha
cis
trans
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA231,547A
Other languages
English (en)
French (fr)
Other versions
CA231547S (fr
Inventor
Jean Bowler
Keith B. Mallion
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of CA1067490A publication Critical patent/CA1067490A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA231,547A 1974-08-05 1975-07-15 Prostanoic acid derivatives Expired CA1067490A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB34334/74A GB1486832A (en) 1974-08-05 1974-08-05 Prostanoic acid derivatives

Publications (1)

Publication Number Publication Date
CA1067490A true CA1067490A (en) 1979-12-04

Family

ID=10364354

Family Applications (1)

Application Number Title Priority Date Filing Date
CA231,547A Expired CA1067490A (en) 1974-08-05 1975-07-15 Prostanoic acid derivatives

Country Status (17)

Country Link
JP (1) JPS51125042A (cs)
AT (1) ATA606175A (cs)
AU (1) AU502146B2 (cs)
BE (1) BE832098A (cs)
CA (1) CA1067490A (cs)
DD (1) DD124595A5 (cs)
DE (1) DE2534989A1 (cs)
DK (1) DK354575A (cs)
FI (1) FI752196A7 (cs)
FR (1) FR2281101A1 (cs)
GB (1) GB1486832A (cs)
IE (1) IE43198B1 (cs)
IN (1) IN141386B (cs)
NL (1) NL7509078A (cs)
NO (1) NO752734L (cs)
SE (1) SE7508779L (cs)
ZA (1) ZA754491B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1554030A (en) * 1976-05-10 1979-10-17 Upjohn Co Prostaglandins
GB8625325D0 (en) * 1986-10-22 1986-11-26 Glaxo Group Ltd Chemical compounds
US5688819A (en) * 1992-09-21 1997-11-18 Allergan Cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US5352708A (en) * 1992-09-21 1994-10-04 Allergan, Inc. Non-acidic cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl derivatives as therapeutic agents
US6184250B1 (en) 1993-08-03 2001-02-06 Alcon Laboratories, Inc. Use of cloprostenol and fluprostenol analogues to treat glaucoma and ocular hypertension
US5510383A (en) * 1993-08-03 1996-04-23 Alcon Laboratories, Inc. Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
WO2025149165A1 (en) * 2024-01-12 2025-07-17 Intervet International B.V. A PROCESS FOR PURIFICATION OF INTERMEDIATES OF PROSTAGLANDIN F2Αα COMPOUNDS AND ITS USE IN THE PREPARATION OF PROSTAGLANDIN F2α COMPOUNDS

Also Published As

Publication number Publication date
IE43198L (en) 1976-02-05
SE7508779L (sv) 1976-02-06
IE43198B1 (en) 1981-01-14
FR2281101B1 (cs) 1978-11-10
FR2281101A1 (fr) 1976-03-05
DE2534989A1 (de) 1976-02-26
AU8310275A (en) 1977-01-20
BE832098A (fr) 1976-02-04
AU502146B2 (en) 1979-07-12
DD124595A5 (cs) 1977-03-02
IN141386B (cs) 1977-02-19
NO752734L (cs) 1976-02-06
GB1486832A (en) 1977-09-28
JPS51125042A (en) 1976-11-01
FI752196A7 (cs) 1976-02-06
NL7509078A (nl) 1976-02-09
ATA606175A (de) 1978-05-15
DK354575A (da) 1976-02-06
ZA754491B (en) 1976-06-30

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