CA1064923A - N-acyl-n-norsalutaridines and process for making them - Google Patents

N-acyl-n-norsalutaridines and process for making them

Info

Publication number
CA1064923A
CA1064923A CA245,309A CA245309A CA1064923A CA 1064923 A CA1064923 A CA 1064923A CA 245309 A CA245309 A CA 245309A CA 1064923 A CA1064923 A CA 1064923A
Authority
CA
Canada
Prior art keywords
aryl
substituted
acyl
alkoxy
norsalutaridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA245,309A
Other languages
English (en)
French (fr)
Inventor
Martin A. Schwartz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FLORIDA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF FLORIDA STATE U NIVERSITY
Original Assignee
FLORIDA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF FLORIDA STATE U NIVERSITY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FLORIDA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF FLORIDA STATE U NIVERSITY filed Critical FLORIDA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF FLORIDA STATE U NIVERSITY
Application granted granted Critical
Publication of CA1064923A publication Critical patent/CA1064923A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/28—Morphinans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA245,309A 1975-02-12 1976-02-09 N-acyl-n-norsalutaridines and process for making them Expired CA1064923A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/549,491 US4003903A (en) 1975-02-12 1975-02-12 N-acyl-N-norsalutaridines and process for making them

Publications (1)

Publication Number Publication Date
CA1064923A true CA1064923A (en) 1979-10-23

Family

ID=24193230

Family Applications (1)

Application Number Title Priority Date Filing Date
CA245,309A Expired CA1064923A (en) 1975-02-12 1976-02-09 N-acyl-n-norsalutaridines and process for making them

Country Status (5)

Country Link
US (1) US4003903A (OSRAM)
CA (1) CA1064923A (OSRAM)
FR (2) FR2301521A1 (OSRAM)
NL (1) NL7601356A (OSRAM)
YU (1) YU31376A (OSRAM)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1982000144A1 (en) * 1980-07-03 1982-01-21 Us Commerce A short total synthesis of dihydrothebainone,dihydrocodeinone,and nordihydrocodeinone
US4368326A (en) * 1980-07-03 1983-01-11 Rice Kenner C Short total synthesis of dihydrothebainone, dihydrocodeinone, and nordihydroccodeinone
US4521601A (en) * 1981-05-20 1985-06-04 The United States Of America As Represented By The Department Of Health & Human Services Practical total synthesis unnatural enantiomers of opium-derived morphinans
US4559403A (en) * 1983-05-19 1985-12-17 Hoffmann-La Roche Inc. Substituted isoquinolines
US4613668A (en) * 1983-12-22 1986-09-23 The United States Of America As Represented By The Department Of Health And Human Services Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl
US6326379B1 (en) 1998-09-16 2001-12-04 Bristol-Myers Squibb Co. Fused pyridine inhibitors of cGMP phosphodiesterase
US7399858B2 (en) * 2002-11-11 2008-07-15 Mallinckrodt Inc. Method for the catalytic production of hydrocodone, hydromorphone, and derivatives thereof
US7323565B2 (en) * 2002-11-11 2008-01-29 Mallinckrodt Inc. Method for the catalytic production of hydrocodone and hydromorphone
US7321038B2 (en) * 2002-11-11 2008-01-22 Mallinckrodt Inc. Method for the catalytic production of hydrocodone and hydromorphone
JP2008533008A (ja) * 2005-03-10 2008-08-21 マリンクロッド・インコーポレイテッド モルフィナンおよびその中間体の製造方法
KR100863692B1 (ko) * 2006-12-08 2008-10-15 울산대학교 산학협력단 퇴행성질환 및 염증질환에 대한 예방치료 효과를 갖는7-하이드록시-6-메톡시-1,2,3,4-테트라하이드로이소퀴놀린유도체
TWI471289B (zh) 2010-06-11 2015-02-01 Rhodes Technologies 使三級胺進行ｎ－脫烷反應之方法
CA2802295C (en) 2010-06-11 2016-09-20 Rhodes Technologies Transition metal-catalyzed processes for the preparation of n-allyl compounds and use thereof
CN110615794B (zh) * 2019-09-20 2022-04-19 甘肃省药物碱厂 一种从罂粟壳中提取分离蒂巴因的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH560194A5 (OSRAM) * 1967-08-25 1975-03-27 Hoffmann La Roche

Also Published As

Publication number Publication date
FR2309537A1 (fr) 1976-11-26
US4003903A (en) 1977-01-18
YU31376A (en) 1983-01-21
NL7601356A (nl) 1976-08-16
FR2301521B1 (OSRAM) 1979-08-31
FR2301521A1 (fr) 1976-09-17
FR2309537B1 (OSRAM) 1979-08-31

Similar Documents

Publication Publication Date Title
CA1064923A (en) N-acyl-n-norsalutaridines and process for making them
US5668285A (en) Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
CA1122976A (en) Tetracyclic compounds
CA1292744C (en) 9-amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments
Gomez-Bengoa et al. Synthesis of isoascididemin, a regioisomer of the marine alkaloid ascididemin
WO1995029919A1 (en) Preparation of a camptothecin derivative by intramolecular cyclisation
JP2023532317A (ja) カンプトテシン誘導体を合成するための中間体及びその製造方法並びに用途
JPS6232749B2 (OSRAM)
Murahashi et al. Rhodium catalyzed hydrogenation of quinolines and isoquinolines under water-gas shift conditions.
CA2067200C (en) Total synthesis of northebaine, normorphine, noroxymorphone enantiomers and derivatives via n-nor intermediates
CA1136130A (en) 14-methoxymorphinan-6-one compounds
Fuentes et al. Synthesis of 2-azacycl [3.2. 2] azine
Saa et al. A regioselective entry to 13-substituted 8-oxoprotoberberines. Total synthesis of (.+-.)-corydaline
CA1055031A (en) Process for the preparation of vincamine and other indole alkaloids
US4045440A (en) Method of producing thebaine from codeine and oripavine from morphine
Repke et al. Synthesis of naucléfine, angustidine, angustine,(±)-13b, 14-dihydro-angustine and naulafine
US4251659A (en) Polyfluorohydroxyisopropyl-heterocyclic compounds
RU2069659C1 (ru) Способ восстановления карбонилсодержащего производного акридина или его фармацевтически приемлемой кислотно-аддитивной соли
SU554816A3 (ru) Способ получени азотсодержащих полициклических соединений или их солей, или рацематов, или оптических антиподов
Brown et al. Centrosymmetric 1, 5-naphthyridine derivatives: synthesis, tautomerism, and thermal rearrangements
CA1114822A (en) Furonaphthyridine compounds
Atanes et al. The intermolecular benzyne cycloaddition (IBC) approach to7-substituted aporphinoids. Mechanistic considerations
US4011231A (en) 2-Phenyl-6-(1-hydroxy-2-t-butylaminoethyl)-4H-pyrido[3,2-d]-1,3-dioxin maleate and its use as an intermediate
CA1167439A (en) Pentacyclic compounds, processes for their preparation and their use
Cho et al. Enantioselective Synthesis of Cryptostyline Ⅰ, Ⅱ and Ⅲ via Asymmetric Reduction