CA1034941A - N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates - Google Patents
N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediatesInfo
- Publication number
- CA1034941A CA1034941A CA193,912A CA193912A CA1034941A CA 1034941 A CA1034941 A CA 1034941A CA 193912 A CA193912 A CA 193912A CA 1034941 A CA1034941 A CA 1034941A
- Authority
- CA
- Canada
- Prior art keywords
- compounds
- processes
- preparation
- methods
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1061373A GB1458372A (en) | 1973-03-05 | 1973-03-05 | Steroid carbamates and allophanates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1034941A true CA1034941A (en) | 1978-07-18 |
Family
ID=9971097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA193,912A Expired CA1034941A (en) | 1973-03-05 | 1974-03-04 | N-nitroso compounds, compositions containing such compounds, processes for their preparation and methods of treatment therewith, and novel intermediates |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3963707A (fi) |
| JP (1) | JPS5613720B2 (fi) |
| AT (1) | AT343293B (fi) |
| BE (1) | BE811775A (fi) |
| CA (1) | CA1034941A (fi) |
| CH (1) | CH606109A5 (fi) |
| DE (1) | DE2409436A1 (fi) |
| DK (1) | DK134915B (fi) |
| ES (1) | ES423694A1 (fi) |
| FI (1) | FI53578C (fi) |
| FR (1) | FR2220261B1 (fi) |
| GB (1) | GB1458372A (fi) |
| HU (1) | HU168811B (fi) |
| IE (1) | IE38909B1 (fi) |
| NL (1) | NL7402961A (fi) |
| NO (1) | NO740747L (fi) |
| SE (1) | SE401513B (fi) |
| SU (1) | SU512714A3 (fi) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1523035A (en) * | 1976-03-10 | 1978-08-31 | Leo Ab | Derivatives of estradiol - 17 - dihydrogen phosphates |
| US4261910A (en) * | 1978-08-14 | 1981-04-14 | Kureha Kagaku Kogyo Kabushiki Kaisha | Process for the preparation of Chlorambucil derivatives |
| DE3210637A1 (de) * | 1982-03-23 | 1983-09-29 | Stiftung Deutsches Krebsforschungszentrum, 6900 Heidelberg | Steroidester von n-(2-halogenethyl)-n-nitroso-carbamoylaminosaeuren und deren peptiden, sowie verfahren zu deren herstellung |
| JPS61293993A (ja) * | 1985-06-21 | 1986-12-24 | Kureha Chem Ind Co Ltd | 新規な螢光物質，その製造方法及び薬剤 |
| US5792758A (en) * | 1995-12-08 | 1998-08-11 | G. D. Searle & Co. | Steroid nitrite ester derivatives useful as anti-inflammatory drugs |
| US5912240A (en) * | 1997-04-10 | 1999-06-15 | Loria; Roger M. | 5-androstene 3β, 17α diol as an inhibitor of tumor growth |
| IT1311922B1 (it) * | 1999-04-13 | 2002-03-20 | Nicox Sa | Composti farmaceutici. |
-
1973
- 1973-03-05 GB GB1061373A patent/GB1458372A/en not_active Expired
-
1974
- 1974-02-20 IE IE00343/74A patent/IE38909B1/xx unknown
- 1974-02-25 US US05/445,572 patent/US3963707A/en not_active Expired - Lifetime
- 1974-02-27 DE DE2409436A patent/DE2409436A1/de not_active Withdrawn
- 1974-02-27 SE SE7402630A patent/SE401513B/xx unknown
- 1974-02-27 ES ES423694A patent/ES423694A1/es not_active Expired
- 1974-02-28 FI FI598/74A patent/FI53578C/fi active
- 1974-03-01 BE BE141559A patent/BE811775A/xx unknown
- 1974-03-04 NO NO740747A patent/NO740747L/no unknown
- 1974-03-04 HU HULE734A patent/HU168811B/hu unknown
- 1974-03-04 CA CA193,912A patent/CA1034941A/en not_active Expired
- 1974-03-04 DK DK114474AA patent/DK134915B/da unknown
- 1974-03-04 JP JP2506274A patent/JPS5613720B2/ja not_active Expired
- 1974-03-04 SU SU2003194A patent/SU512714A3/ru active
- 1974-03-05 CH CH311774A patent/CH606109A5/xx not_active IP Right Cessation
- 1974-03-05 FR FR7407462A patent/FR2220261B1/fr not_active Expired
- 1974-03-05 AT AT181074A patent/AT343293B/de not_active IP Right Cessation
- 1974-03-05 NL NL7402961A patent/NL7402961A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES423694A1 (es) | 1976-04-16 |
| IE38909L (en) | 1974-09-05 |
| FI53578C (fi) | 1978-06-12 |
| DE2409436A1 (de) | 1974-09-12 |
| JPS5029549A (fi) | 1975-03-25 |
| FR2220261A1 (fi) | 1974-10-04 |
| HU168811B (fi) | 1976-07-28 |
| ATA181074A (de) | 1977-09-15 |
| DK134915C (fi) | 1977-06-27 |
| CH606109A5 (fi) | 1978-10-13 |
| AT343293B (de) | 1978-05-26 |
| BE811775A (fr) | 1974-07-01 |
| US3963707A (en) | 1976-06-15 |
| NO740747L (no) | 1974-09-06 |
| SE401513B (sv) | 1978-05-16 |
| GB1458372A (en) | 1976-12-15 |
| IE38909B1 (en) | 1978-06-21 |
| FI53578B (fi) | 1978-02-28 |
| NL7402961A (fi) | 1974-09-09 |
| JPS5613720B2 (fi) | 1981-03-30 |
| FR2220261B1 (fi) | 1978-02-03 |
| DK134915B (da) | 1977-02-07 |
| SU512714A3 (ru) | 1976-04-30 |
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