CA1034044A - Tertiary alcohol stabilized e-series prostaglandins - Google Patents

Tertiary alcohol stabilized e-series prostaglandins

Info

Publication number
CA1034044A
CA1034044A CA224,982A CA224982A CA1034044A CA 1034044 A CA1034044 A CA 1034044A CA 224982 A CA224982 A CA 224982A CA 1034044 A CA1034044 A CA 1034044A
Authority
CA
Canada
Prior art keywords
tertiary alcohol
series prostaglandins
alcohol stabilized
stabilized
prostaglandins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA224,982A
Other languages
English (en)
French (fr)
Inventor
Donald C. Monkhouse
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1034044A publication Critical patent/CA1034044A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA224,982A 1974-04-19 1975-04-18 Tertiary alcohol stabilized e-series prostaglandins Expired CA1034044A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US462213A US3927197A (en) 1974-04-19 1974-04-19 Tertiary alcohol stabilized E-series prostaglandins

Publications (1)

Publication Number Publication Date
CA1034044A true CA1034044A (en) 1978-07-04

Family

ID=23835600

Family Applications (1)

Application Number Title Priority Date Filing Date
CA224,982A Expired CA1034044A (en) 1974-04-19 1975-04-18 Tertiary alcohol stabilized e-series prostaglandins

Country Status (23)

Country Link
US (1) US3927197A (hu)
JP (1) JPS5337408B2 (hu)
AR (1) AR213271A1 (hu)
AT (1) AT348130B (hu)
AU (1) AU470631B2 (hu)
BE (1) BE828065A (hu)
BG (1) BG35326A3 (hu)
CA (1) CA1034044A (hu)
CS (1) CS191244B2 (hu)
DD (1) DD119131A5 (hu)
DE (1) DE2516105C3 (hu)
DK (1) DK138161B (hu)
ES (1) ES436613A1 (hu)
FI (1) FI62220C (hu)
FR (1) FR2267760B1 (hu)
GB (1) GB1474852A (hu)
HU (1) HU175405B (hu)
IE (1) IE40829B1 (hu)
IL (1) IL46994A (hu)
LU (1) LU72320A1 (hu)
NL (1) NL158384B (hu)
PH (1) PH11697A (hu)
SE (1) SE428528B (hu)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4197257A (en) * 1976-02-04 1980-04-08 The Upjohn Company 6-Keto prostaglandin derivatives
US4169895A (en) * 1976-09-28 1979-10-02 Pfizer Inc. Antisecretory 16,16-dimethyl-17-oxaprostaglandins
US4098805A (en) * 1977-04-11 1978-07-04 The Upjohn Company 9-deoxy-9-methylene-pgf-type amides
ZA831186B (en) * 1982-03-22 1983-11-30 Upjohn Ltd Gelled pge2/triacetin solutions
ZA837627B (en) * 1982-10-15 1984-06-27 Procter & Gamble Storage stable topical pharmaceutical composition containing low dielectric solvents
US5409911A (en) * 1992-09-11 1995-04-25 Merck & Co., Inc. Prostaglandin analog for treating osteoporosis
PT725642E (pt) * 1993-10-27 2000-05-31 Upjohn Co Prostaglandina e 1 estabilizada
HN1996000101A (es) 1996-02-28 1997-06-26 Inc Pfizer Terapia combinada para la osteoporosis
US6121253A (en) * 1998-11-20 2000-09-19 Merck Frosst Canada & Co. Prostaglandin conjugates for treating or preventing bone disease
US20050203086A1 (en) * 2004-03-04 2005-09-15 Pfizer Inc. Methods of treatment using an EP2 selective receptor agonist
US20100099640A1 (en) * 2007-05-04 2010-04-22 Joannes Geuns Tissue degeneration protection
US9005183B2 (en) * 2007-05-16 2015-04-14 Health Knight, Llc System and method for treating erectile dysfunction
AT515356B1 (de) * 2014-01-30 2015-11-15 Gebro Holding Gmbh Stabile alkoholische Lösung von Alprostadil
MX2020008680A (es) 2018-02-21 2020-09-25 Ai Therapeutics Inc Terapia de combinacion con apilimod y agentes glutamatergicos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3644638A (en) * 1970-08-24 1972-02-22 American Home Prod Compositions and methods for relieving bronchial spasm with prostanoic acids and esters
US3749800A (en) * 1971-11-01 1973-07-31 Upjohn Co Stable composition for dispensing pge2
US3833725A (en) * 1972-12-08 1974-09-03 Syntex Corp Dialkylated glycol compositions and medicament preparations containing same

Also Published As

Publication number Publication date
IL46994A0 (en) 1975-06-25
SE428528B (sv) 1983-07-11
FI751108A (hu) 1975-10-20
IE40829L (en) 1975-10-19
US3927197A (en) 1975-12-16
DE2516105B2 (de) 1981-01-08
FR2267760B1 (hu) 1978-08-04
SE7503723L (sv) 1975-10-20
IL46994A (en) 1979-10-31
GB1474852A (en) 1977-05-25
FR2267760A1 (hu) 1975-11-14
AR213271A1 (es) 1979-01-15
NL7504274A (nl) 1975-10-21
IE40829B1 (en) 1979-08-29
FI62220B (fi) 1982-08-31
PH11697A (en) 1978-05-24
DD119131A5 (hu) 1976-04-12
AU7987775A (en) 1976-03-25
DE2516105A1 (de) 1975-10-23
DK138161C (hu) 1979-01-02
JPS5337408B2 (hu) 1978-10-09
BG35326A3 (en) 1984-03-15
HU175405B (hu) 1980-07-28
JPS50145515A (hu) 1975-11-21
AU470631B2 (en) 1976-03-25
LU72320A1 (hu) 1976-03-17
CS191244B2 (en) 1979-06-29
NL158384B (nl) 1978-11-15
DK138161B (da) 1978-07-24
BE828065A (fr) 1975-10-17
DK167075A (hu) 1975-10-20
DE2516105C3 (de) 1982-01-07
FI62220C (fi) 1982-12-10
ES436613A1 (es) 1977-04-16
AT348130B (de) 1979-01-25
ATA278875A (de) 1978-06-15

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