ATA278875A - Verfahren zur herstellung einer stabilisierten pharmazeutischen zusammensetzung unter einsatz von pge1, pge2 oder pge2-carboxamid h - Google Patents
Verfahren zur herstellung einer stabilisierten pharmazeutischen zusammensetzung unter einsatz von pge1, pge2 oder pge2-carboxamid hInfo
- Publication number
- ATA278875A ATA278875A AT278875A AT278875A ATA278875A AT A278875 A ATA278875 A AT A278875A AT 278875 A AT278875 A AT 278875A AT 278875 A AT278875 A AT 278875A AT A278875 A ATA278875 A AT A278875A
- Authority
- AT
- Austria
- Prior art keywords
- pge2
- pge1
- carboxamide
- preparing
- pharmaceutical composition
- Prior art date
Links
- GMVPRGQOIOIIMI-UHFFFAOYSA-N (8R,11R,12R,13E,15S)-11,15-Dihydroxy-9-oxo-13-prostenoic acid Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CCCCCCC(O)=O GMVPRGQOIOIIMI-UHFFFAOYSA-N 0.000 title 1
- 229960000711 alprostadil Drugs 0.000 title 1
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 title 1
- 229960002986 dinoprostone Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- GMVPRGQOIOIIMI-DWKJAMRDSA-N prostaglandin E1 Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O GMVPRGQOIOIIMI-DWKJAMRDSA-N 0.000 title 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US462213A US3927197A (en) | 1974-04-19 | 1974-04-19 | Tertiary alcohol stabilized E-series prostaglandins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ATA278875A true ATA278875A (de) | 1978-06-15 |
| AT348130B AT348130B (de) | 1979-01-25 |
Family
ID=23835600
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT278875A AT348130B (de) | 1974-04-19 | 1975-04-11 | Verfahren zur herstellung einer stabilisierten pharmazeutischen zusammensetzung unter einsatz von pge1, pge2 oder pge2-carboxamid h |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US3927197A (de) |
| JP (1) | JPS5337408B2 (de) |
| AR (1) | AR213271A1 (de) |
| AT (1) | AT348130B (de) |
| AU (1) | AU470631B2 (de) |
| BE (1) | BE828065A (de) |
| BG (1) | BG35326A3 (de) |
| CA (1) | CA1034044A (de) |
| CS (1) | CS191244B2 (de) |
| DD (1) | DD119131A5 (de) |
| DE (1) | DE2516105C3 (de) |
| DK (1) | DK138161B (de) |
| ES (1) | ES436613A1 (de) |
| FI (1) | FI62220C (de) |
| FR (1) | FR2267760B1 (de) |
| GB (1) | GB1474852A (de) |
| HU (1) | HU175405B (de) |
| IE (1) | IE40829B1 (de) |
| IL (1) | IL46994A (de) |
| LU (1) | LU72320A1 (de) |
| NL (1) | NL158384B (de) |
| PH (1) | PH11697A (de) |
| SE (1) | SE428528B (de) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4197257A (en) * | 1976-02-04 | 1980-04-08 | The Upjohn Company | 6-Keto prostaglandin derivatives |
| US4169895A (en) * | 1976-09-28 | 1979-10-02 | Pfizer Inc. | Antisecretory 16,16-dimethyl-17-oxaprostaglandins |
| US4098805A (en) * | 1977-04-11 | 1978-07-04 | The Upjohn Company | 9-deoxy-9-methylene-pgf-type amides |
| ZA831186B (en) * | 1982-03-22 | 1983-11-30 | Upjohn Ltd | Gelled pge2/triacetin solutions |
| ZA837627B (en) * | 1982-10-15 | 1984-06-27 | Procter & Gamble | Storage stable topical pharmaceutical composition containing low dielectric solvents |
| US5409911A (en) * | 1992-09-11 | 1995-04-25 | Merck & Co., Inc. | Prostaglandin analog for treating osteoporosis |
| PT725642E (pt) * | 1993-10-27 | 2000-05-31 | Upjohn Co | Prostaglandina e 1 estabilizada |
| HN1996000101A (es) | 1996-02-28 | 1997-06-26 | Inc Pfizer | Terapia combinada para la osteoporosis |
| US6121253A (en) * | 1998-11-20 | 2000-09-19 | Merck Frosst Canada & Co. | Prostaglandin conjugates for treating or preventing bone disease |
| US20050203086A1 (en) * | 2004-03-04 | 2005-09-15 | Pfizer Inc. | Methods of treatment using an EP2 selective receptor agonist |
| US20100099640A1 (en) * | 2007-05-04 | 2010-04-22 | Joannes Geuns | Tissue degeneration protection |
| US9005183B2 (en) * | 2007-05-16 | 2015-04-14 | Health Knight, Llc | System and method for treating erectile dysfunction |
| AT515356B1 (de) * | 2014-01-30 | 2015-11-15 | Gebro Holding Gmbh | Stabile alkoholische Lösung von Alprostadil |
| MX2020008680A (es) | 2018-02-21 | 2020-09-25 | Ai Therapeutics Inc | Terapia de combinacion con apilimod y agentes glutamatergicos. |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3644638A (en) * | 1970-08-24 | 1972-02-22 | American Home Prod | Compositions and methods for relieving bronchial spasm with prostanoic acids and esters |
| US3749800A (en) * | 1971-11-01 | 1973-07-31 | Upjohn Co | Stable composition for dispensing pge2 |
| US3833725A (en) * | 1972-12-08 | 1974-09-03 | Syntex Corp | Dialkylated glycol compositions and medicament preparations containing same |
-
1974
- 1974-04-19 US US462213A patent/US3927197A/en not_active Expired - Lifetime
-
1975
- 1975-03-14 IE IE564/75A patent/IE40829B1/xx unknown
- 1975-04-01 IL IL46994A patent/IL46994A/xx unknown
- 1975-04-01 SE SE7503723A patent/SE428528B/xx unknown
- 1975-04-03 GB GB1375075A patent/GB1474852A/en not_active Expired
- 1975-04-07 AU AU79877/75A patent/AU470631B2/en not_active Expired
- 1975-04-07 PH PH17025A patent/PH11697A/en unknown
- 1975-04-10 NL NL7504274.A patent/NL158384B/xx not_active IP Right Cessation
- 1975-04-11 AT AT278875A patent/AT348130B/de not_active IP Right Cessation
- 1975-04-12 DE DE2516105A patent/DE2516105C3/de not_active Expired
- 1975-04-15 ES ES436613A patent/ES436613A1/es not_active Expired
- 1975-04-15 FI FI751108A patent/FI62220C/fi not_active IP Right Cessation
- 1975-04-17 CS CS752679A patent/CS191244B2/cs unknown
- 1975-04-17 BE BE1006596A patent/BE828065A/xx not_active IP Right Cessation
- 1975-04-17 BG BG7529696A patent/BG35326A3/xx unknown
- 1975-04-18 CA CA224,982A patent/CA1034044A/en not_active Expired
- 1975-04-18 HU HU75PI465A patent/HU175405B/hu unknown
- 1975-04-18 DD DD185553A patent/DD119131A5/xx unknown
- 1975-04-18 LU LU72320A patent/LU72320A1/xx unknown
- 1975-04-18 AR AR258417A patent/AR213271A1/es active
- 1975-04-18 JP JP4736775A patent/JPS5337408B2/ja not_active Expired
- 1975-04-18 FR FR7512160A patent/FR2267760B1/fr not_active Expired
- 1975-04-18 DK DK167075AA patent/DK138161B/da not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL46994A0 (en) | 1975-06-25 |
| SE428528B (sv) | 1983-07-11 |
| FI751108A (de) | 1975-10-20 |
| IE40829L (en) | 1975-10-19 |
| CA1034044A (en) | 1978-07-04 |
| US3927197A (en) | 1975-12-16 |
| DE2516105B2 (de) | 1981-01-08 |
| FR2267760B1 (de) | 1978-08-04 |
| SE7503723L (sv) | 1975-10-20 |
| IL46994A (en) | 1979-10-31 |
| GB1474852A (en) | 1977-05-25 |
| FR2267760A1 (de) | 1975-11-14 |
| AR213271A1 (es) | 1979-01-15 |
| NL7504274A (nl) | 1975-10-21 |
| IE40829B1 (en) | 1979-08-29 |
| FI62220B (fi) | 1982-08-31 |
| PH11697A (en) | 1978-05-24 |
| DD119131A5 (de) | 1976-04-12 |
| AU7987775A (en) | 1976-03-25 |
| DE2516105A1 (de) | 1975-10-23 |
| DK138161C (de) | 1979-01-02 |
| JPS5337408B2 (de) | 1978-10-09 |
| BG35326A3 (en) | 1984-03-15 |
| HU175405B (hu) | 1980-07-28 |
| JPS50145515A (de) | 1975-11-21 |
| AU470631B2 (en) | 1976-03-25 |
| LU72320A1 (de) | 1976-03-17 |
| CS191244B2 (en) | 1979-06-29 |
| NL158384B (nl) | 1978-11-15 |
| DK138161B (da) | 1978-07-24 |
| BE828065A (fr) | 1975-10-17 |
| DK167075A (de) | 1975-10-20 |
| DE2516105C3 (de) | 1982-01-07 |
| FI62220C (fi) | 1982-12-10 |
| ES436613A1 (es) | 1977-04-16 |
| AT348130B (de) | 1979-01-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |