CA1031710A - Synthese de fortimicine a a partir de micromonospora olivoasterospora - Google Patents

Synthese de fortimicine a a partir de micromonospora olivoasterospora

Info

Publication number
CA1031710A
CA1031710A CA205,200A CA205200A CA1031710A CA 1031710 A CA1031710 A CA 1031710A CA 205200 A CA205200 A CA 205200A CA 1031710 A CA1031710 A CA 1031710A
Authority
CA
Canada
Prior art keywords
fortimicin
micromonospora olivoasterospora
olivoasterospora
micromonospora
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA205,200A
Other languages
English (en)
Inventor
Isao Kawamoto
Mitsuyoshi Yamamoto
Takashi Nara
Seiji Sato
Tomoyasu Sato
Ryo Okachi
Seigo Takasawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of CA1031710A publication Critical patent/CA1031710A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/863—Mycobacterium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
CA205,200A 1973-07-23 1974-07-19 Synthese de fortimicine a a partir de micromonospora olivoasterospora Expired CA1031710A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP48080866A JPS5145675B2 (fr) 1973-07-23 1973-07-23

Publications (1)

Publication Number Publication Date
CA1031710A true CA1031710A (fr) 1978-05-23

Family

ID=13730251

Family Applications (1)

Application Number Title Priority Date Filing Date
CA205,200A Expired CA1031710A (fr) 1973-07-23 1974-07-19 Synthese de fortimicine a a partir de micromonospora olivoasterospora

Country Status (19)

Country Link
US (1) US3976768A (fr)
JP (1) JPS5145675B2 (fr)
AR (1) AR202939A1 (fr)
AT (1) AT330353B (fr)
BE (1) BE817954A (fr)
CA (1) CA1031710A (fr)
CH (1) CH593335A5 (fr)
DE (1) DE2435160C3 (fr)
DK (1) DK137960B (fr)
ES (1) ES428500A1 (fr)
FR (1) FR2238502B1 (fr)
GB (1) GB1473356A (fr)
IN (1) IN139807B (fr)
NL (1) NL158224B (fr)
NO (1) NO142264C (fr)
NZ (1) NZ174950A (fr)
PH (1) PH14048A (fr)
SE (1) SE420215B (fr)
ZA (1) ZA744416B (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5218888A (en) * 1975-08-01 1977-02-12 Kyowa Hakko Kogyo Co Ltd Preparation of fortimicin c
US4097428A (en) * 1975-08-01 1978-06-27 Abbott Laboratories Fortimicin C and process for production thereof
US4091032A (en) * 1976-09-23 1978-05-23 Abbott Laboratories 4-N-acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
JPS6011718B2 (ja) * 1976-09-23 1985-03-27 協和醗酵工業株式会社 新規なホ−テイマイシンｂの誘導体およびその製法
US4188319A (en) * 1976-09-23 1980-02-12 Abbott Laboratories 4-N-Acylfortimicin B derivatives and the chemical conversion of fortimicin B to fortimicin A
US4206206A (en) * 1977-03-24 1980-06-03 Kowa Company, Ltd. Antibiotics of the KA-6606 series and pharmaceutical compositions thereof
JPS53141244A (en) * 1977-05-11 1978-12-08 Kyowa Hakko Kogyo Co Ltd Novel hortemycin derivatives
JPS5736157Y2 (fr) * 1977-05-20 1982-08-10
JPS5488240A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative
US4176178A (en) * 1977-12-21 1979-11-27 Abbott Laboratories 2-Deoxy-2'-N-acyl and alkyl fortimicins A and B
US4187298A (en) * 1977-12-21 1980-02-05 Abbott Laboratories 2'N-acyl and alkyl fortimicin B and derivatives, 4,2'-N,N'diacyl and dialkyl fortimicin B derivatives 4-N-acyl-2'-N-alkyl and 4-N-alkyl-2'-N-acyl fortimicin B derivatives
US4192867A (en) * 1977-12-21 1980-03-11 Abbott Laboratories 2-Deoxyfortimicin A, 4-N-alkyl and 4-N-acyl-2-deoxyfortimicin B derivatives
US4169198A (en) * 1977-12-21 1979-09-25 Abbott Laboratories 2-Deoxyfortimicin B
US4187296A (en) * 1977-12-21 1980-02-05 Abbott Laboratories 2-N-acyl and alkyl 6-epi-fortimicin B and derivatives
US4187297A (en) * 1977-12-21 1980-02-05 Abbott Laboratories 3-De-O-methyl-2-N-acyl and alkyl fortimicins A and B
JPS5488241A (en) * 1977-12-21 1979-07-13 Kyowa Hakko Kogyo Co Ltd Novel fortimicin a derivative
US4214075A (en) * 1977-12-21 1980-07-22 Abbott Laboratories 6'-Epi-fortimicin A and B derivatives
US4196197A (en) * 1977-12-21 1980-04-01 Abbott Laboratories 2'N-Acyl and alkyl-6'-N-alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
US4187299A (en) * 1977-12-21 1980-02-05 Abbott Laboratories Fortimicin E
US4214076A (en) * 1977-12-21 1980-07-22 Abbott Laboratories 2'-N-Substituted fortimicin B and derivatives
US4183920A (en) * 1977-12-21 1980-01-15 Abbott Laboratories 4-N-Acyl, 2'-N-acyl and 4,2'-N,N'-diacylfortimicin E derivatives
US4207314A (en) * 1977-12-21 1980-06-10 Abbott Laboratories Isofortimicin
US4205070A (en) * 1977-12-21 1980-05-27 Abbott Laboratories 6'N-Alkyl- and 6',6'-di-N-alkyl derivatives of fortimicins A and B
JPS6041679B2 (ja) * 1978-03-03 1985-09-18 協和醗酵工業株式会社 新抗生物質ホ−テイマイシンｋｇ↓１，ｋｇ↓２およびｋｇ↓３ならびにそれらの製造法
US4312858A (en) * 1978-07-13 1982-01-26 Kowa Company, Ltd. Antibiotic KA-7038 and compositions containing same
JPS5564597A (en) * 1978-11-06 1980-05-15 Meiji Seika Kaisha Ltd New antibiotic substance sf-2052 and its preparation
US4226980A (en) * 1978-12-07 1980-10-07 Abbott Laboratories Novel derivatives of fortimicin B and process for preparing same
US4208407A (en) * 1979-02-05 1980-06-17 Abbott Laboratories 5-Deoxyfortimicin A, 2,5-dideoxyfortimicin A and the corresponding 4-N-acyl and alkyl fortimicin B derivatives thereof and intermediates therefor
US4219644A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicins AH and AI
US4219643A (en) * 1979-03-29 1980-08-26 Abbott Laboratories Fortimicin AN
US4252972A (en) * 1979-09-26 1981-02-24 Abbott Laboratories Fortimicin B-1,2:4,5-bis-carbamates
US4263429A (en) * 1979-09-26 1981-04-21 Abbott Laboratories 1,2,6-Tri-N-benzyloxycarbonylfortimicin B-4,5-carbamate and 1,2,6-tri-N-acetylfortimicin B-4,5-carbamate
US4382926A (en) * 1980-04-01 1983-05-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Formimidoyl A and B useful as semi-synthetic aminoglycosidic antibiotics
US5900406A (en) * 1991-07-09 1999-05-04 Nzym, Inc. Use of antibiotics of the type 2-deoxystreptamine substituted with aminosugars to inhibit growth of microorganisms containing group I introns

Also Published As

Publication number Publication date
FR2238502B1 (fr) 1977-07-08
BE817954A (fr) 1975-01-22
AR202939A1 (es) 1975-07-31
SE7409443L (sv) 1975-01-24
DK137960C (fr) 1978-11-06
JPS5145675B2 (fr) 1976-12-04
NL158224B (nl) 1978-10-16
AU7118974A (en) 1976-01-15
ES428500A1 (es) 1976-12-01
NL7409879A (nl) 1975-01-27
DE2435160C3 (de) 1980-04-10
DK387474A (fr) 1975-03-10
CH593335A5 (fr) 1977-11-30
ATA603974A (de) 1975-09-15
SE420215B (sv) 1981-09-21
US3976768A (en) 1976-08-24
JPS5029789A (fr) 1975-03-25
NO142264B (no) 1980-04-14
NO142264C (no) 1980-07-23
GB1473356A (en) 1977-05-11
NO742634L (fr) 1975-02-17
DK137960B (da) 1978-06-12
IN139807B (fr) 1976-07-31
DE2435160B2 (de) 1979-08-09
NZ174950A (en) 1978-04-28
AT330353B (de) 1976-06-25
FR2238502A1 (fr) 1975-02-21
ZA744416B (en) 1975-07-30
DE2435160A1 (de) 1975-02-06
PH14048A (en) 1980-12-29

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