CA1030522A - D-homo-20-keto-pregnanes - Google Patents

D-homo-20-keto-pregnanes

Info

Publication number
CA1030522A
CA1030522A CA215,097A CA215097A CA1030522A CA 1030522 A CA1030522 A CA 1030522A CA 215097 A CA215097 A CA 215097A CA 1030522 A CA1030522 A CA 1030522A
Authority
CA
Canada
Prior art keywords
pregnanes
keto
homo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA215,097A
Other languages
English (en)
French (fr)
Other versions
CA215097S (en
Inventor
Klaus Kieslich
Karl Petzoldt
Rudolf Wiechert
Reinhard Horowski
Gert Paschelke
Dieter Palenschat
Ulrich Kerb
Helmut Wachtel
Wolfgang Kehr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2360443A external-priority patent/DE2360443A1/de
Priority claimed from DE19742445161 external-priority patent/DE2445161A1/de
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1030522A publication Critical patent/CA1030522A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
CA215,097A 1973-11-30 1974-12-02 D-homo-20-keto-pregnanes Expired CA1030522A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2360443A DE2360443A1 (de) 1973-11-30 1973-11-30 D-homo-20-ketopregnane
DE19742445161 DE2445161A1 (de) 1974-09-19 1974-09-19 D-homo-20-ketopregnane ii

Publications (1)

Publication Number Publication Date
CA1030522A true CA1030522A (en) 1978-05-02

Family

ID=25766200

Family Applications (1)

Application Number Title Priority Date Filing Date
CA215,097A Expired CA1030522A (en) 1973-11-30 1974-12-02 D-homo-20-keto-pregnanes

Country Status (14)

Country Link
US (1) US4045574A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5084561A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) AT347611B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1030522A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CH (1) CH618183A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (1) DD115659A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK134348C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES432106A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2253512B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB1494097A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE40423B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL46153A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NL (1) NL7415577A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SE (1) SE408426B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879316A (en) * 1987-02-26 1989-11-07 The University Of Tennessee Research Corporation Interpenetrating polymer network ion exchange membranes and method for preparing same
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
WO2004016640A2 (en) * 2002-08-16 2004-02-26 Pharmacia & Upjohn Company Llc 5 ANDROSTEN-3β-OL STEROID INTERMEDIATES AND PROCESSES FOR THEIR PREPARATION
AU2014256229B2 (en) 2013-04-17 2018-10-04 Sage Therapeutics, Inc. 19-nor C3,3-disubstituted C21-N-pyrazolyl steroids and methods of use thereof
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
EP2986624B1 (en) 2013-04-17 2020-03-25 Sage Therapeutics, Inc. 19-nor neuroactive steroids for methods of treatment
RU2754534C2 (ru) 2013-07-19 2021-09-03 Сейдж Терапьютикс, Инк. Нейроактивные стероиды, композиции и их использование
EP3035940B1 (en) 2013-08-23 2018-10-17 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
IL315006A (en) 2014-10-16 2024-10-01 Sage Therapeutics Inc Compounds and compositions comprising thereof for treating cns disorders
AU2015331597B2 (en) 2014-10-16 2020-04-30 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
LT3224269T (lt) 2014-11-27 2020-07-10 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti cns sutrikimams gydyti
HUE054092T2 (hu) 2015-01-26 2021-08-30 Sage Therapeutics Inc Központi idegrendszeri zavarok kezelésére szolgáló kompozíciók és eljárások
JP6875996B2 (ja) 2015-02-20 2021-05-26 セージ セラピューティクス， インコーポレイテッド 神経刺激性ステロイド、組成物、およびその使用
AU2017296295B2 (en) 2016-07-11 2022-02-24 Sage Therapeutics, Inc. C7, C12, and C16 substituted neuroactive steroids and their methods of use
EP4302764A3 (en) 2016-07-11 2024-06-26 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
KR20200104349A (ko) * 2017-12-22 2020-09-03 세이지 테라퓨틱스, 인크. Cns 장애의 치료를 위한 조성물 및 방법
MA54594A (fr) 2018-12-05 2022-04-06 Sage Therapeutics Inc Stéroïdes neuroactifs et leurs procédés d'utilisation
MX2021014515A (es) 2019-05-31 2022-03-22 Sage Therapeutics Inc Esteroides neuroactivos y composiciones de estos.
CN114787174A (zh) * 2019-06-27 2022-07-22 萨奇治疗股份有限公司 用于治疗cns病症的组合物和方法
US20230257415A1 (en) * 2019-06-27 2023-08-17 Sage Therapeutics, Inc. Compounds for treating cns disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof
US3686223A (en) * 1968-12-26 1972-08-22 Sterling Drug Inc D-homoestratrienes
US3833621A (en) * 1972-03-20 1974-09-03 Richardson Merrell Inc 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same

Also Published As

Publication number Publication date
JPS5084561A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-07-08
SE408426B (sv) 1979-06-11
NL7415577A (nl) 1975-06-03
SE7414960L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-06-02
GB1494097A (en) 1977-12-07
IL46153A0 (en) 1975-02-10
FR2253512A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-07-04
IL46153A (en) 1979-01-31
ATA950774A (de) 1978-05-15
AU7586774A (en) 1976-06-03
AT347611B (de) 1979-01-10
ES432106A1 (es) 1976-11-01
DK134348C (da) 1977-03-21
CH618183A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1980-07-15
DD115659A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-10-12
FR2253512B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1978-02-03
IE40423B1 (en) 1979-05-23
DK604174A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1975-07-28
IE40423L (en) 1975-05-30
DK134348B (da) 1976-10-25
US4045574A (en) 1977-08-30

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