CA1025856A - Quinoline-3-carboxamidotetrazole derivatives - Google Patents

Quinoline-3-carboxamidotetrazole derivatives

Info

Publication number
CA1025856A
CA1025856A CA193,476A CA193476A CA1025856A CA 1025856 A CA1025856 A CA 1025856A CA 193476 A CA193476 A CA 193476A CA 1025856 A CA1025856 A CA 1025856A
Authority
CA
Canada
Prior art keywords
carboxamidotetrazole
quinoline
derivatives
carboxamidotetrazole derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,476A
Other languages
English (en)
French (fr)
Other versions
CA193476S (en
Inventor
David M. Waters
Gwynn P. Ellis
Mervyn E. Peel
Heulwen M. Ridgway
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Allen and Hanburys Ltd
Original Assignee
Allen and Hanburys Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Allen and Hanburys Ltd filed Critical Allen and Hanburys Ltd
Application granted granted Critical
Publication of CA1025856A publication Critical patent/CA1025856A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • C07D215/56Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3 with oxygen atoms in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA193,476A 1973-02-26 1974-02-26 Quinoline-3-carboxamidotetrazole derivatives Expired CA1025856A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB924973A GB1433774A (en) 1973-02-26 1973-02-26 Heterocyclic compounds apparatus for conveying articles

Publications (1)

Publication Number Publication Date
CA1025856A true CA1025856A (en) 1978-02-07

Family

ID=9868317

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,476A Expired CA1025856A (en) 1973-02-26 1974-02-26 Quinoline-3-carboxamidotetrazole derivatives

Country Status (14)

Country Link
JP (1) JPS5029574A (enrdf_load_html_response)
AT (1) AT329562B (enrdf_load_html_response)
AU (1) AU474797B2 (enrdf_load_html_response)
BE (1) BE811246A (enrdf_load_html_response)
CA (1) CA1025856A (enrdf_load_html_response)
CH (1) CH602707A5 (enrdf_load_html_response)
DE (1) DE2407744A1 (enrdf_load_html_response)
FR (1) FR2218896B1 (enrdf_load_html_response)
GB (1) GB1433774A (enrdf_load_html_response)
IE (1) IE38886B1 (enrdf_load_html_response)
LU (1) LU69479A1 (enrdf_load_html_response)
NL (1) NL7402613A (enrdf_load_html_response)
SE (1) SE7401984L (enrdf_load_html_response)
ZA (1) ZA74883B (enrdf_load_html_response)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8765957B2 (en) 2009-03-20 2014-07-01 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US9701639B2 (en) 2014-10-07 2017-07-11 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator
US9931334B2 (en) 2005-12-28 2018-04-03 Vertex Pharmaceuticals Incorporated Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US10272046B2 (en) 2012-02-27 2019-04-30 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US10646481B2 (en) 2008-08-13 2020-05-12 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2324304A2 (fr) * 1975-09-22 1977-04-15 Roussel Uclaf Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
US4186201A (en) 1977-02-07 1980-01-29 Riker Laboratories, Inc. Methods of using 8(tetrazol-5-ylcarbamoyl)isoquinoline compounds
US4264604A (en) 1977-07-01 1981-04-28 Ciba-Geigy Corporation Quinolonecarboxylic acid derivatives as bactericides
US4390541A (en) 1980-12-19 1983-06-28 Lilly Industries Limited Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease
FR2509728A1 (fr) * 1981-07-17 1983-01-21 Roussel Uclaf Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
US4377579A (en) 1981-12-03 1983-03-22 Minnesota Mining And Manufacturing Company N-(Tetrazol-5-yl)phenazine-1-carboxamides
FR2537140B1 (fr) * 1982-12-07 1986-07-18 Roussel Uclaf Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant
DE3875820T2 (de) * 1987-01-20 1993-03-18 Dainippon Pharmaceutical Co Aromatische heterozyklische karbonsaeureamidabkoemmlinge, verfahren zur herstellung und arzneimittel, die diese enthalten.
US4959363A (en) * 1989-06-23 1990-09-25 Sterling Drug Inc. Quinolonecarboxamide compounds, their preparation and use as antivirals.
US6034100A (en) * 1993-03-10 2000-03-07 Otsuka Pharmaceutical Co., Ltd. Method for inhibiting cytokine secretion
US6143760A (en) 1997-08-25 2000-11-07 Neurogen Corporation Substituted 4-oxo-napthyridine-3-carboxamides: GABA brain receptor ligands
IL134291A0 (en) * 1997-08-25 2001-04-30 Neurogen Corp Substituted 4-oxo-napthyridine-3- carboxamides as gaba brain receptor ligands
WO1999043661A2 (en) * 1998-02-26 1999-09-02 Neurogen Corporation Substituted cycloalkyl-4-oxonicotinic carboxamides; gaba brain receptor ligands
JP4532263B2 (ja) * 2002-05-14 2010-08-25 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 置換されたキノロンカルボン酸、その誘導体、作用の部位、およびその使用
MXPA06000675A (es) 2003-07-24 2006-04-19 Astellas Pharma Inc Derivado de quinolona o sal del mismo.
US8354427B2 (en) 2004-06-24 2013-01-15 Vertex Pharmaceutical Incorporated Modulators of ATP-binding cassette transporters
BRPI0511321B8 (pt) * 2004-06-24 2021-05-25 Vertex Pharma moduladores de transportadores de cassete de ligação de atp, composição farmacêutica e seus usos
EP3216787B1 (en) * 2004-06-24 2020-02-19 Vertex Pharmaceuticals Incorporated Intermediates for the preparation of modulators of atp-binding cassette transporters
RU2528046C2 (ru) * 2004-06-24 2014-09-10 Вертекс Фармасьютикалз Инкорпорейтед Модуляторы транспортеров атф-связывающей кассеты
US8802700B2 (en) 2010-12-10 2014-08-12 Vertex Pharmaceuticals Incorporated Modulators of ATP-Binding Cassette transporters
WO2013129622A1 (ja) 2012-03-02 2013-09-06 武田薬品工業株式会社 複素環化合物およびその用途
WO2014077401A1 (ja) 2012-11-19 2014-05-22 武田薬品工業株式会社 含窒素複素環化合物
CN105330602B (zh) * 2015-12-07 2018-02-09 江南大学 一种癸氧喹酯类似物及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1383088A (en) * 1972-07-03 1975-02-05 Allen & Hanburys Ltd Pharmacologically active quinaldamide derivatives

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11291662B2 (en) 2005-12-28 2022-04-05 Vertex Pharmaceuticals Incorporated Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US9931334B2 (en) 2005-12-28 2018-04-03 Vertex Pharmaceuticals Incorporated Solid forms of N[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US10537565B2 (en) 2005-12-28 2020-01-21 Vertex Pharmaceuticals Incorporated Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
US10646481B2 (en) 2008-08-13 2020-05-12 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US8835639B2 (en) 2009-03-20 2014-09-16 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US9371287B2 (en) 2009-03-20 2016-06-21 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US9751839B2 (en) 2009-03-20 2017-09-05 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US8765957B2 (en) 2009-03-20 2014-07-01 Vertex Pharmaceuticals Incorporated Process for making modulators of cystic fibrosis transmembrane conductance regulator
US11147770B2 (en) 2012-02-27 2021-10-19 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US10272046B2 (en) 2012-02-27 2019-04-30 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US11752106B2 (en) 2012-02-27 2023-09-12 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US12214083B2 (en) 2012-02-27 2025-02-04 Vertex Pharmaceuticals Incorporated Pharmaceutical composition and administrations thereof
US9701639B2 (en) 2014-10-07 2017-07-11 Vertex Pharmaceuticals Incorporated Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator

Also Published As

Publication number Publication date
FR2218896A1 (enrdf_load_html_response) 1974-09-20
BE811246A (fr) 1974-08-19
DE2407744A1 (de) 1974-08-29
JPS5029574A (enrdf_load_html_response) 1975-03-25
IE38886L (en) 1974-08-26
FR2218896B1 (enrdf_load_html_response) 1977-09-09
SE7401984L (enrdf_load_html_response) 1974-08-27
AT329562B (de) 1976-05-25
CH602707A5 (enrdf_load_html_response) 1978-07-31
AU6559274A (en) 1975-08-14
ZA74883B (en) 1974-12-24
IE38886B1 (en) 1978-06-21
LU69479A1 (enrdf_load_html_response) 1975-05-21
ATA149974A (de) 1975-08-15
NL7402613A (enrdf_load_html_response) 1974-08-28
GB1433774A (en) 1976-04-28
AU474797B2 (en) 1976-08-05

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