CA1024145A - Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil - Google Patents

Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil

Info

Publication number
CA1024145A
CA1024145A CA223,644A CA223644A CA1024145A CA 1024145 A CA1024145 A CA 1024145A CA 223644 A CA223644 A CA 223644A CA 1024145 A CA1024145 A CA 1024145A
Authority
CA
Canada
Prior art keywords
furanyl
fluorouracil
tetrahydro
synthesizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA223,644A
Other languages
English (en)
French (fr)
Other versions
CA223644S (en
Inventor
Leroy B. Townsend
Robert A. Earl
Steven J. Manning
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Utah
Original Assignee
University of Utah
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Utah filed Critical University of Utah
Application granted granted Critical
Publication of CA1024145A publication Critical patent/CA1024145A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA223,644A 1974-05-06 1975-04-02 Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil Expired CA1024145A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/467,538 US3960864A (en) 1974-05-06 1974-05-06 Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil

Publications (1)

Publication Number Publication Date
CA1024145A true CA1024145A (en) 1978-01-10

Family

ID=23856104

Family Applications (1)

Application Number Title Priority Date Filing Date
CA223,644A Expired CA1024145A (en) 1974-05-06 1975-04-02 Method of synthesizing 1-(tetrahydro-2-furanyl)-5-fluorouracil

Country Status (14)

Country Link
US (1) US3960864A (de)
JP (1) JPS50151884A (de)
AT (1) AT337203B (de)
CA (1) CA1024145A (de)
CH (1) CH610897A5 (de)
DE (1) DE2519201A1 (de)
DK (1) DK137759C (de)
ES (1) ES437481A1 (de)
FR (1) FR2279746A1 (de)
GB (1) GB1503614A (de)
IL (1) IL47033A (de)
NL (1) NL7505305A (de)
NO (1) NO141993C (de)
ZA (1) ZA752145B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2648239C3 (de) * 1975-10-24 1981-11-12 Rikagaku Kenkyusho, Wako, Saitama Di-(trialkylstannyl)-pyrimidinderivate, Verfahren zu ihrer Herstellung und Verfahren zu ihrer Weiterverarbeitung zu nucleosidartigen Pyrimidinderivaten
JPS5259174A (en) * 1975-11-10 1977-05-16 Asahi Chem Ind Co Ltd Preparation of n-substituted uracil compounds
IE45046B1 (en) * 1975-11-28 1982-06-16 Takeda Chemical Industries Ltd Method of producing 5-fluorouracil derivatives
US4324895A (en) * 1975-12-04 1982-04-13 Rikagaku Kenkyusho Novel process for producing pyrimidine nucleosides and novel pyrimidine nucleosides obtained thereby
DK142415B (da) * 1975-12-24 1980-10-27 Mitsui Toatsu Chemicals Fremgangsmåde til fremstilling af 1-(2-tetrahydrofuryl)-5-fluoruracil.
CN103159746B (zh) * 2011-12-12 2015-09-02 山东新时代药业有限公司 一种工业法合成替加氟的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1168391A (en) * 1968-01-08 1969-10-22 Inst Organocheskogo Sinteza An Substituted Uracils

Also Published As

Publication number Publication date
GB1503614A (en) 1978-03-15
FR2279746B1 (de) 1979-07-06
NL7505305A (nl) 1975-11-10
DK137759B (da) 1978-05-01
NO141993C (no) 1980-06-11
DK197175A (da) 1975-11-07
ES437481A1 (es) 1977-07-01
FR2279746A1 (fr) 1976-02-20
CH610897A5 (de) 1979-05-15
US3960864A (en) 1976-06-01
JPS50151884A (de) 1975-12-06
NO141993B (no) 1980-03-03
ZA752145B (en) 1976-03-31
AU7993375A (en) 1976-10-14
AT337203B (de) 1977-06-27
ATA305175A (de) 1976-10-15
IL47033A0 (en) 1975-06-25
DE2519201A1 (de) 1975-11-20
IL47033A (en) 1978-06-15
NO751217L (de) 1975-11-07
DK137759C (da) 1978-10-02

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