CA1021352A - Substituted 2-aminomethyl-4,6-dihalophenols - Google Patents

Substituted 2-aminomethyl-4,6-dihalophenols

Info

Publication number
CA1021352A
CA1021352A CA130,146A CA130146A CA1021352A CA 1021352 A CA1021352 A CA 1021352A CA 130146 A CA130146 A CA 130146A CA 1021352 A CA1021352 A CA 1021352A
Authority
CA
Canada
Prior art keywords
dihalophenols
aminomethyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA130,146A
Other languages
English (en)
Other versions
CA130146S (en
Inventor
Everett M. Schultz
Edward J. (Jr.) Cragoe
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of CA1021352A publication Critical patent/CA1021352A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/56—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups
    • C07C47/565—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing hydroxy groups all hydroxy groups bound to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA130,146A 1970-12-23 1971-12-14 Substituted 2-aminomethyl-4,6-dihalophenols Expired CA1021352A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US101195A US3864401A (en) 1970-12-23 1970-12-23 Substituted 2-aminomethyl-4,6-dihalophenols

Publications (1)

Publication Number Publication Date
CA1021352A true CA1021352A (en) 1977-11-22

Family

ID=22283451

Family Applications (1)

Application Number Title Priority Date Filing Date
CA130,146A Expired CA1021352A (en) 1970-12-23 1971-12-14 Substituted 2-aminomethyl-4,6-dihalophenols

Country Status (9)

Country Link
US (1) US3864401A (enExample)
JP (1) JPS566983B1 (enExample)
AU (1) AU472440B2 (enExample)
CA (1) CA1021352A (enExample)
CH (1) CH567452A5 (enExample)
DE (1) DE2163911C3 (enExample)
FR (1) FR2119067B1 (enExample)
GB (1) GB1360420A (enExample)
NL (1) NL175172C (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT332863B (de) 1973-01-02 1976-10-25 Gerot Pharmazeutika Verfahren zur herstellung von neuen 2-aminomethyl-4,6-dihalogenphenolderivaten sowie deren additionssalzen mit sauren
US3996279A (en) 1973-01-02 1976-12-07 Gerot-Pharmazeutika Dr. Walter Otto K.G. Novel 2-amino methyl-4,6-dihalogenphenol derivatives and methods for the preparation thereof
US3979361A (en) * 1974-02-20 1976-09-07 Merck & Co., Inc. 2-Aminomethyl-6-trihalo-methylphenols
US4044153A (en) * 1975-08-01 1977-08-23 Merck & Co., Inc. Antiinflammatory 2-aminomethyl-6-trihalomethylphenols
US4029816A (en) * 1975-11-25 1977-06-14 Merck & Co., Inc. Substituted 2-aminomethyl-6-iodophenols
GB1551619A (en) * 1976-12-09 1979-08-30 Shell Int Research Process for the preperation of oximes
US4312887A (en) * 1978-10-25 1982-01-26 Abbott Laboratories 2-Hydroxylaminomethyl phenols
JPS6143153A (ja) * 1984-08-06 1986-03-01 Yoshitomi Pharmaceut Ind Ltd オルト−アミノメチルフエノ−ル誘導体
US6858615B2 (en) 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20090253714A1 (en) * 2003-08-20 2009-10-08 Johnson Michael R Methods of reducing risk of infection from pathogens
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
US20070021439A1 (en) * 2005-07-25 2007-01-25 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens with soluble amide and ester pyrazinoylguanidine sodium channel blockers
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
RU2671976C2 (ru) 2012-12-17 2018-11-08 Пэрион Сайенсиз, Инк. Соединения 3,5-диамино-6-хлор-n-(n-(4-фенилбутил)карбамимидоил)пиразин-2-карбоксамида
HUE032891T2 (hu) 2012-12-17 2017-11-28 Parion Sciences Inc Klórpirazin-karboxamid-származékok nem kielégítõ nyálkahártya-hidratáció által elõsegített megbetegedések kezelésére
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds
JP6236500B1 (ja) * 2016-06-30 2017-11-22 誠哉 佐藤 止水プラグ装置

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3118941A (en) * 1962-04-02 1964-01-21 Abbott Lab N-(diethylaminoethyl)-n-propargylbenzylamines
US3419390A (en) * 1965-05-03 1968-12-31 Eastman Kodak Co Elements and developers for color photography utilizing phenolic couplers containingan aminoalkyl group on the coupling position

Also Published As

Publication number Publication date
FR2119067A1 (enExample) 1972-08-04
NL175172C (nl) 1984-10-01
AU472440B2 (en) 1976-05-27
NL7116916A (enExample) 1972-06-27
US3864401A (en) 1975-02-04
DE2163911A1 (de) 1972-07-13
AU3684371A (en) 1973-06-21
NL175172B (nl) 1984-05-01
JPS566983B1 (enExample) 1981-02-14
DE2163911B2 (de) 1974-02-28
CH567452A5 (enExample) 1975-10-15
GB1360420A (en) 1974-07-17
DE2163911C3 (de) 1974-10-03
FR2119067B1 (enExample) 1975-04-18

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