CA1012148A - Process for the production of new imidazole derivatives - Google Patents

Process for the production of new imidazole derivatives

Info

Publication number
CA1012148A
CA1012148A CA141,520A CA141520A CA1012148A CA 1012148 A CA1012148 A CA 1012148A CA 141520 A CA141520 A CA 141520A CA 1012148 A CA1012148 A CA 1012148A
Authority
CA
Canada
Prior art keywords
production
imidazole derivatives
new imidazole
new
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA141,520A
Other languages
English (en)
Other versions
CA141520S (en
Inventor
Konrad Fitzi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH687571A external-priority patent/CH554415A/xx
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA1012148A publication Critical patent/CA1012148A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
CA141,520A 1971-05-10 1972-05-08 Process for the production of new imidazole derivatives Expired CA1012148A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH687571A CH554415A (de) 1970-06-01 1971-05-10 Verfahren zur herstellung von zitronensaeure durch submerse gaerung.
CH696771A CH561202A5 (no) 1971-05-10 1971-05-11
CH697571 1971-05-12
CH425072A CH579072A5 (no) 1971-05-10 1972-03-22

Publications (1)

Publication Number Publication Date
CA1012148A true CA1012148A (en) 1977-06-14

Family

ID=27428754

Family Applications (1)

Application Number Title Priority Date Filing Date
CA141,520A Expired CA1012148A (en) 1971-05-10 1972-05-08 Process for the production of new imidazole derivatives

Country Status (10)

Country Link
AT (4) AT319939B (no)
AU (1) AU472065B2 (no)
BE (1) BE783244A (no)
CA (1) CA1012148A (no)
CH (5) CH561716A5 (no)
DE (1) DE2221546A1 (no)
FR (1) FR2137740B1 (no)
GB (1) GB1381031A (no)
NL (1) NL7206346A (no)
SE (1) SE405731B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK513580A (da) * 1980-01-07 1981-07-08 Du Pont Fremgangsmaade til fremstilling af 4,5-diaryl-alfa (polyhalogenalkyl)-1h-imidazol-2-methanoler
GR75287B (no) * 1980-07-25 1984-07-13 Ciba Geigy Ag
US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols
WO1983002613A1 (en) * 1981-07-20 1983-08-04 Sallmann, Alfred Trisubstituted oxazo compounds
AU554104B2 (en) * 1981-09-01 1986-08-07 F. Hoffmann-La Roche Ag Heterocyclic compounds and fungicides containing same
EP0084756A1 (de) * 1982-01-22 1983-08-03 Ciba-Geigy Ag Trisubstituierte Oxazaverbindungen
EP0084757A1 (de) * 1982-01-25 1983-08-03 Ciba-Geigy Ag Trisubstituierte Diaza-Derivate
IL83467A0 (en) * 1986-08-15 1988-01-31 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for their preparation and pharmaceutical compositions containing the same
US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
US5656644A (en) * 1994-07-20 1997-08-12 Smithkline Beecham Corporation Pyridyl imidazoles
ES2053401B1 (es) * 1992-01-13 1995-03-01 Smithkline Beecham Corp Compuestos de imidazol y procedimientos para su prepacion.
MX9300141A (es) * 1992-01-13 1994-07-29 Smithkline Beecham Corp Compuestos de imidazol novedosos, procedimiento para su preparacion y composiciones farmaceuticas que lo contienen.
DE69433501T2 (de) * 1993-11-08 2004-11-04 Smithkline Beecham Corp. Oxazole zur behandlung von zytokinvermittelten erkrankungen
US6426360B1 (en) * 1994-07-28 2002-07-30 G D Searle & Co. 4,5-substituted imidazolyl compounds for the treatment of inflammation
US5620999A (en) * 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
EP0797575B1 (en) * 1994-12-13 2003-10-15 F. Hoffmann-La Roche Ag Imidazole derivatives as protein kinase inhibitors in particular egf-r tyrosine kinase
TW492959B (en) * 1997-04-18 2002-07-01 Merck & Co Inc Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors
US6127545A (en) * 1997-04-18 2000-10-03 Merck & Co., Inc. Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
US6130334A (en) * 1998-04-15 2000-10-10 Merck & Co., Inc. Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
DE60001229T2 (de) * 1999-04-09 2003-10-30 Smithkline Beecham Corp Triarylimidazole
AR029803A1 (es) * 2000-02-21 2003-07-16 Smithkline Beecham Plc Imidazoles sustituidos con piridilo y composiciones farmaceuticas que las comprenden
GB0007405D0 (en) * 2000-03-27 2000-05-17 Smithkline Beecham Corp Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192211A (en) * 1962-05-03 1965-06-29 Nl Combinatie Chem Ind 5-phenyl-5-(2-pyrazyl)-hydantoin
US3538104A (en) * 1969-02-28 1970-11-03 Geigy Chem Corp Pyridyl-2-imidazolones

Also Published As

Publication number Publication date
AU4205572A (en) 1973-11-15
CH579072A5 (no) 1976-08-31
AT319940B (de) 1975-01-10
AU472065B2 (en) 1976-05-13
NL7206346A (no) 1972-11-14
AT316544B (de) 1974-07-10
SE405731B (sv) 1978-12-27
FR2137740A1 (no) 1972-12-29
BE783244A (fr) 1972-11-10
FR2137740B1 (no) 1975-08-01
GB1381031A (en) 1975-01-22
CH561716A5 (no) 1975-05-15
AT319939B (de) 1975-01-10
CH561718A5 (no) 1975-05-15
DE2221546A1 (de) 1972-11-16
CH561717A5 (no) 1975-05-15
CH561202A5 (no) 1975-04-30
AT319941B (de) 1975-01-10

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