CA1008084A - Procede de preparation de nouveaux acylamino acides - Google Patents

Procede de preparation de nouveaux acylamino acides

Info

Publication number
CA1008084A
CA1008084A CA170,311A CA170311A CA1008084A CA 1008084 A CA1008084 A CA 1008084A CA 170311 A CA170311 A CA 170311A CA 1008084 A CA1008084 A CA 1008084A
Authority
CA
Canada
Prior art keywords
making new
new acid
acid acylamino
acylamino
making
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA170,311A
Other languages
English (en)
French (fr)
Other versions
CA170311S (en
Inventor
Jacques Duhault
Georges Remond
Xavier Pascaud
Michel Vincent
Laszlo Beregi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Application granted granted Critical
Publication of CA1008084A publication Critical patent/CA1008084A/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24—Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/58—Preparation of carboxylic acid halides
    • C07C51/60—Preparation of carboxylic acid halides by conversion of carboxylic acids or their anhydrides or esters, lactones, salts into halides with the same carboxylic acid part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA170,311A 1972-05-05 1973-05-03 Procede de preparation de nouveaux acylamino acides Expired CA1008084A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2109572A GB1406054A (en) 1972-05-05 1972-05-05 Acylamino acids and their derivatives and process for preparing them and pharmaceutical compositions

Publications (1)

Publication Number Publication Date
CA1008084A true CA1008084A (fr) 1977-04-05

Family

ID=10157139

Family Applications (1)

Application Number Title Priority Date Filing Date
CA170,311A Expired CA1008084A (fr) 1972-05-05 1973-05-03 Procede de preparation de nouveaux acylamino acides

Country Status (18)

Country Link
US (1) US3876683A (zh)
JP (1) JPS5246222B2 (zh)
AR (1) AR197040A1 (zh)
AT (1) AT323136B (zh)
BE (1) BE799144A (zh)
CA (1) CA1008084A (zh)
CH (1) CH576425A5 (zh)
ES (1) ES414362A1 (zh)
FR (1) FR2183765B1 (zh)
GB (1) GB1406054A (zh)
HU (1) HU165742B (zh)
IE (1) IE37586B1 (zh)
NL (1) NL7306141A (zh)
NO (1) NO140421C (zh)
OA (1) OA04368A (zh)
SE (1) SE408057B (zh)
SU (1) SU489310A3 (zh)
ZA (1) ZA733012B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341798A (en) * 1980-07-22 1982-07-27 Laboratori Prophin S.P.A. Amide derivatives of p-isobutyl-phenyl-propionic acids and related pharmaceutical compositions
JPS6322657Y2 (zh) * 1981-04-21 1988-06-22
GB2177769B (en) * 1985-07-17 1989-07-26 Guest John D Improvements in or relating to hose connectors
US6153652A (en) 1996-11-22 2000-11-28 Elan Pharmaceuticals, Inc. N-(aryl/heteroaryl/alkylacetyl) amino acid amides, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6642261B2 (en) 1997-11-21 2003-11-04 Athena Neurosciences, Inc. N-(aryl/heteroarylacety) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds
US6117901A (en) 1996-11-22 2000-09-12 Athena Neurosciences, Inc. N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3043868A (en) * 1959-12-09 1962-07-10 Searle & Co N-xenylalkanoylaminoalkanoic acids and esters thereof
US3770821A (en) * 1970-10-16 1973-11-06 Miles Lab Substituted beta-arylamidoacrylic acids

Also Published As

Publication number Publication date
ZA733012B (en) 1974-03-27
JPS5246222B2 (zh) 1977-11-22
SE7306289L (zh) 1973-09-06
SE408057B (sv) 1979-05-14
NO140421B (no) 1979-05-21
SU489310A3 (ru) 1975-10-25
ES414362A1 (es) 1976-02-01
DE2321392B2 (de) 1976-07-29
GB1406054A (en) 1975-09-10
DE2321392A1 (de) 1973-11-15
AT323136B (de) 1975-06-25
US3876683A (en) 1975-04-08
AR197040A1 (es) 1974-03-08
HU165742B (zh) 1974-10-28
AU5425273A (en) 1974-10-10
JPS4947353A (zh) 1974-05-08
FR2183765B1 (zh) 1976-05-14
IE37586L (en) 1973-11-05
OA04368A (fr) 1980-01-31
BE799144A (fr) 1973-11-05
NO140421C (no) 1979-08-29
NL7306141A (zh) 1973-11-07
CH576425A5 (zh) 1976-06-15
IE37586B1 (en) 1977-08-31
FR2183765A1 (zh) 1973-12-21

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