CA1002041A - Analgesics obtained by reacting a primary amine and an aldehyde - Google Patents

Analgesics obtained by reacting a primary amine and an aldehyde

Info

Publication number
CA1002041A
CA1002041A CA162,346A CA162346A CA1002041A CA 1002041 A CA1002041 A CA 1002041A CA 162346 A CA162346 A CA 162346A CA 1002041 A CA1002041 A CA 1002041A
Authority
CA
Canada
Prior art keywords
analgesics
aldehyde
reacting
primary amine
amine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA162,346A
Other languages
English (en)
Other versions
CA162346S (en
Inventor
Georges Negrevergne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cortial SA
Original Assignee
Cortial SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cortial SA filed Critical Cortial SA
Application granted granted Critical
Publication of CA1002041A publication Critical patent/CA1002041A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA162,346A 1972-01-27 1973-01-24 Analgesics obtained by reacting a primary amine and an aldehyde Expired CA1002041A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7202644A FR2168931B1 (de) 1972-01-27 1972-01-27

Publications (1)

Publication Number Publication Date
CA1002041A true CA1002041A (en) 1976-12-21

Family

ID=9092513

Family Applications (1)

Application Number Title Priority Date Filing Date
CA162,346A Expired CA1002041A (en) 1972-01-27 1973-01-24 Analgesics obtained by reacting a primary amine and an aldehyde

Country Status (9)

Country Link
US (1) US3947587A (de)
JP (1) JPS4947332A (de)
BE (1) BE794081A (de)
CA (1) CA1002041A (de)
CH (1) CH563382A5 (de)
DE (1) DE2303521A1 (de)
ES (1) ES410871A1 (de)
FR (1) FR2168931B1 (de)
NL (1) NL7300893A (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4176198A (en) 1977-10-06 1979-11-27 William H. Rorer, Inc. Method of treatment
US4187317A (en) * 1977-10-06 1980-02-05 William H. Rorer, Inc. Sunscreen and erythema treating with N-benzylidene anilenes
FR2431489A1 (fr) * 1978-07-18 1980-02-15 Unicler Bases de schiff derivees de pyridyl-aldehydes et leur application en tant que medicaments
CA1132567A (en) * 1978-08-08 1982-09-28 Pieter T. Haken Phenyliminomethylpyridine derivatives
FR2476644A1 (fr) * 1980-02-21 1981-08-28 Sarget Lab Orthoarylydeneaminophenethylamine, leur preparation et leur utilisation therapeutique
DE3110009A1 (de) * 1981-03-11 1982-09-30 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue benzofuran-derivate, ihre herstellung und verwendung
FR2531082A1 (fr) * 1982-07-29 1984-02-03 Cortial Nouvelles ((phenyl-4 piperazinylethyl)-2-anilino)-3 isobenzofurannones, leur methode de preparation et leur application therapeutique
US6437092B1 (en) * 1998-11-06 2002-08-20 Conjuchem, Inc. Conjugates of opioids and endogenous carriers

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (de) * 1965-03-18
GB1173312A (en) * 1966-03-17 1969-12-10 Kefalas As Heterocyclic Compounds
US3478097A (en) * 1966-04-29 1969-11-11 Sperry Rand Corp Polyhalogenated salicylidene anilines
US3472743A (en) * 1966-12-19 1969-10-14 Du Pont Zinc plating baths and additives therefor

Also Published As

Publication number Publication date
BE794081A (fr) 1973-05-16
CH563382A5 (de) 1975-06-30
DE2303521A1 (de) 1973-08-09
NL7300893A (de) 1973-07-31
FR2168931A1 (de) 1973-09-07
JPS4947332A (de) 1974-05-08
US3947587A (en) 1976-03-30
ES410871A1 (es) 1976-06-16
FR2168931B1 (de) 1975-03-14

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