BRPI1006611A2 - "n' -(metilsulfonil)-1 - [tiofen-2-il]-1, 4-dihidropiridina -3- carbohidrazida, composto de fórmula (i), composição farmacêutica, método de tratamento de uma neuropatia e uso de um composto" - Google Patents
"n' -(metilsulfonil)-1 - [tiofen-2-il]-1, 4-dihidropiridina -3- carbohidrazida, composto de fórmula (i), composição farmacêutica, método de tratamento de uma neuropatia e uso de um composto"Info
- Publication number
- BRPI1006611A2 BRPI1006611A2 BRPI1006611A BRPI1006611A BRPI1006611A2 BR PI1006611 A2 BRPI1006611 A2 BR PI1006611A2 BR PI1006611 A BRPI1006611 A BR PI1006611A BR PI1006611 A BRPI1006611 A BR PI1006611A BR PI1006611 A2 BRPI1006611 A2 BR PI1006611A2
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- carbohydrazide
- dihydropyridine
- thiophen
- methylsulfonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/56—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1207MU2009 | 2009-05-07 | ||
| PCT/IN2010/000295 WO2010128528A2 (en) | 2009-05-07 | 2010-05-06 | Novel heterocyclic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1006611A2 true BRPI1006611A2 (pt) | 2016-04-19 |
Family
ID=42937397
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1006611A BRPI1006611A2 (pt) | 2009-05-07 | 2010-05-06 | "n' -(metilsulfonil)-1 - [tiofen-2-il]-1, 4-dihidropiridina -3- carbohidrazida, composto de fórmula (i), composição farmacêutica, método de tratamento de uma neuropatia e uso de um composto" |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20120046317A1 (pt) |
| EP (1) | EP2427432A2 (pt) |
| JP (1) | JP2012526103A (pt) |
| KR (1) | KR20120018185A (pt) |
| CN (1) | CN102459175A (pt) |
| AR (1) | AR080267A1 (pt) |
| AU (1) | AU2010245596A1 (pt) |
| BR (1) | BRPI1006611A2 (pt) |
| CA (1) | CA2764232A1 (pt) |
| EA (1) | EA201171368A1 (pt) |
| IL (1) | IL216092A0 (pt) |
| MX (1) | MX2011011650A (pt) |
| SG (1) | SG175422A1 (pt) |
| TW (1) | TW201102380A (pt) |
| WO (1) | WO2010128528A2 (pt) |
| ZA (1) | ZA201108702B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104744351B (zh) * | 2014-09-30 | 2017-06-06 | 三峡大学 | 一种小分子抑制剂及在抑制鸟氨酸脱羧酶(odc)上的应用 |
| HUE044889T2 (hu) * | 2015-04-08 | 2019-11-28 | Torrent Pharmaceuticals Ltd | Gyógyászati készítmények |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4758583A (en) | 1984-03-19 | 1988-07-19 | The Rockefeller University | Method and agents for inhibiting protein aging |
| GB8714789D0 (en) * | 1987-06-24 | 1987-07-29 | Lundbeck & Co As H | Heterocyclic compounds |
| JPH08502508A (ja) * | 1992-10-23 | 1996-03-19 | メルク シヤープ エンド ドーム リミテツド | ドーパミンレセプターサブタイプリガンド |
| ATE245420T1 (de) | 1995-01-18 | 2003-08-15 | Alteon Inc | Verwendung von thiazoliumverbindungen zum verhindern und umkehren der bildung von endprodukten der fortgeschrittenen glykosylierung |
| US5656261A (en) | 1995-01-18 | 1997-08-12 | The Picower Institute For Medical Research | Preventing and reversing advanced glycosylation endproducts |
| HU227523B1 (en) | 1999-10-06 | 2011-07-28 | Torrent Pharmaceuticals Ltd | Pyridinium derivatives for the management of aging-related and diabetic vascular complications, process for their preparation and therapeutic uses thereof |
| CN1329597A (zh) * | 1999-10-06 | 2002-01-02 | 托伦脱药品有限公司 | 治疗糖尿病及衰老相关性血管性并发症的吡啶鎓衍生物 |
| ES2243389T3 (es) * | 2001-03-21 | 2005-12-01 | Torrent Pharmaceuticals Ltd | Compuestos de piridinio utiles para el tratamiento de enfermedades relacionadas con los age. |
| DE60201740T2 (de) * | 2001-04-05 | 2005-11-03 | Torrent Pharmaceuticals Ltd., Ahmedabad | Heterocyclische verbindungen für alterungs und diabetes bedingte vasculare erkrankungen |
| HUP0104831A2 (hu) * | 2001-10-19 | 2003-08-28 | Torrent Pharmaceuticals Ltd. | Készítmény és eljárás piridíniumszármazékok gyógyászati alkalmazására |
| KR100437972B1 (ko) * | 2001-10-27 | 2004-07-02 | 한국과학기술연구원 | 피롤리디논 유도체, 이의 제조 방법 및 이를 포함하는제약 조성물 |
| MX2009011499A (es) * | 2007-04-24 | 2009-11-09 | Solvay Pharm Bv | Compuestos heterociclicos con afinidad por los receptores muscarinicos. |
-
2010
- 2010-05-06 BR BRPI1006611A patent/BRPI1006611A2/pt not_active Application Discontinuation
- 2010-05-06 EP EP10747952.9A patent/EP2427432A2/en not_active Withdrawn
- 2010-05-06 KR KR1020117029260A patent/KR20120018185A/ko not_active Application Discontinuation
- 2010-05-06 AU AU2010245596A patent/AU2010245596A1/en not_active Abandoned
- 2010-05-06 MX MX2011011650A patent/MX2011011650A/es not_active Application Discontinuation
- 2010-05-06 US US13/318,740 patent/US20120046317A1/en not_active Abandoned
- 2010-05-06 SG SG2011080140A patent/SG175422A1/en unknown
- 2010-05-06 TW TW099114530A patent/TW201102380A/zh unknown
- 2010-05-06 JP JP2012509152A patent/JP2012526103A/ja active Pending
- 2010-05-06 EA EA201171368A patent/EA201171368A1/ru unknown
- 2010-05-06 WO PCT/IN2010/000295 patent/WO2010128528A2/en active Application Filing
- 2010-05-06 CA CA2764232A patent/CA2764232A1/en not_active Abandoned
- 2010-05-06 CN CN201080027757XA patent/CN102459175A/zh active Pending
- 2010-05-07 AR ARP100101563A patent/AR080267A1/es unknown
-
2011
- 2011-11-01 IL IL216092A patent/IL216092A0/en unknown
- 2011-11-25 ZA ZA2011/08702A patent/ZA201108702B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2010245596A1 (en) | 2011-12-22 |
| AR080267A1 (es) | 2012-03-28 |
| EA201171368A1 (ru) | 2012-04-30 |
| US20120046317A1 (en) | 2012-02-23 |
| WO2010128528A2 (en) | 2010-11-11 |
| IL216092A0 (en) | 2012-01-31 |
| JP2012526103A (ja) | 2012-10-25 |
| CN102459175A (zh) | 2012-05-16 |
| EP2427432A2 (en) | 2012-03-14 |
| KR20120018185A (ko) | 2012-02-29 |
| WO2010128528A9 (en) | 2011-03-03 |
| ZA201108702B (en) | 2012-09-26 |
| TW201102380A (en) | 2011-01-16 |
| MX2011011650A (es) | 2012-02-21 |
| WO2010128528A3 (en) | 2010-12-23 |
| CA2764232A1 (en) | 2010-11-11 |
| SG175422A1 (en) | 2011-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |