BRPI0923645A2 - processo para preparar um composto derivado de quinazolina e forma cristalina de monoidrato. - Google Patents

processo para preparar um composto derivado de quinazolina e forma cristalina de monoidrato.

Info

Publication number
BRPI0923645A2
BRPI0923645A2 BRPI0923645A BRPI0923645A BRPI0923645A2 BR PI0923645 A2 BRPI0923645 A2 BR PI0923645A2 BR PI0923645 A BRPI0923645 A BR PI0923645A BR PI0923645 A BRPI0923645 A BR PI0923645A BR PI0923645 A2 BRPI0923645 A2 BR PI0923645A2
Authority
BR
Brazil
Prior art keywords
monohydrate
preparing
crystalline form
derivative compound
quinazoline derivative
Prior art date
Application number
BRPI0923645A
Other languages
English (en)
Inventor
Motoyuki Hagihara
Shoji Shinomoto
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of BRPI0923645A2 publication Critical patent/BRPI0923645A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0923645A 2008-12-25 2009-12-24 processo para preparar um composto derivado de quinazolina e forma cristalina de monoidrato. BRPI0923645A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2008330600 2008-12-25
PCT/JP2009/071445 WO2010074150A1 (ja) 2008-12-25 2009-12-24 キナゾリン誘導体の製造方法

Publications (1)

Publication Number Publication Date
BRPI0923645A2 true BRPI0923645A2 (pt) 2016-08-02

Family

ID=42287757

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0923645A BRPI0923645A2 (pt) 2008-12-25 2009-12-24 processo para preparar um composto derivado de quinazolina e forma cristalina de monoidrato.

Country Status (10)

Country Link
US (1) US8426589B2 (pt)
EP (1) EP2374801A4 (pt)
JP (1) JP5752420B2 (pt)
KR (1) KR101638645B1 (pt)
CN (1) CN102264708B (pt)
BR (1) BRPI0923645A2 (pt)
CA (1) CA2745150C (pt)
MX (1) MX2011006900A (pt)
TW (1) TWI466872B (pt)
WO (1) WO2010074150A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9951051B2 (en) 2014-05-29 2018-04-24 Shionogi & Co., Ltd. Process for producing alkynylketone derivative
CN105017162B (zh) * 2015-06-26 2017-10-27 陕西师范大学 4‑对丙烯基苯氨基喹唑啉衍生物及其在制备抗肿瘤药物中的应用
DK3330267T3 (da) * 2015-07-29 2022-03-14 Shionogi & Co Salt af quinazolinderivat eller crystal deraf samt fremgangsmåde til fremstilling af salt af quinazolinderivat eller crystal deraf
EP3574906A4 (en) 2017-01-30 2021-01-20 Shionogi & Co., Ltd. SOLID PREPARATION WITH CHINAZOLINE DERIVATIVE

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2431843T3 (es) 2005-02-23 2013-11-28 Shionogi & Co., Ltd. Derivado de quinazolina que tiene actividad inhibidora de tirosina quinasa

Also Published As

Publication number Publication date
EP2374801A4 (en) 2012-08-15
WO2010074150A1 (ja) 2010-07-01
KR101638645B1 (ko) 2016-07-11
US20110257391A1 (en) 2011-10-20
MX2011006900A (es) 2011-07-20
US8426589B2 (en) 2013-04-23
CN102264708A (zh) 2011-11-30
JPWO2010074150A1 (ja) 2012-06-21
CA2745150A1 (en) 2010-07-01
TWI466872B (zh) 2015-01-01
TW201028387A (en) 2010-08-01
JP5752420B2 (ja) 2015-07-22
KR20110103438A (ko) 2011-09-20
CN102264708B (zh) 2015-02-25
CA2745150C (en) 2016-08-09
EP2374801A1 (en) 2011-10-12

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2495 DE 30-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.