BRPI0919245A2 - Vacina para malária - Google Patents

Vacina para malária

Info

Publication number
BRPI0919245A2
BRPI0919245A2 BRPI0919245A BRPI0919245A BRPI0919245A2 BR PI0919245 A2 BRPI0919245 A2 BR PI0919245A2 BR PI0919245 A BRPI0919245 A BR PI0919245A BR PI0919245 A BRPI0919245 A BR PI0919245A BR PI0919245 A2 BRPI0919245 A2 BR PI0919245A2
Authority
BR
Brazil
Prior art keywords
malaria
fertilization
immunogenic compositions
malaria vaccine
vaccine
Prior art date
Application number
BRPI0919245A
Other languages
English (en)
Inventor
Evelina Angov
Nirbhay Kumar
Original Assignee
Us Gov Sec Army
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Sec Army, Univ Johns Hopkins filed Critical Us Gov Sec Army
Publication of BRPI0919245A2 publication Critical patent/BRPI0919245A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • C07K16/205—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

vacina para malária. a presente invenção refere-se a composições imunogênicas baseadas nos antígenos de pré-fertilização ou de pós-fertilização expressos nos gametócitos circulantes no sangue periférico de pessoas infectadas ou nos estágios de desenvolvimento de parasitas da malária no intestino inter mediário do mosquito incluindo gametas do sexo masculino e do sexo feminino extracelulares, zigoto fertilizado e oocineto. a invenção apresenta ainda processos para a prevenção da transmissão de malária utilizando as compo- sições imunogênicas da invenção.
BRPI0919245A 2008-09-24 2009-07-22 Vacina para malária BRPI0919245A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9965108P 2008-09-24 2008-09-24
PCT/US2009/004243 WO2010036293A1 (en) 2008-09-24 2009-07-22 Malaria vaccine

Publications (1)

Publication Number Publication Date
BRPI0919245A2 true BRPI0919245A2 (pt) 2021-11-03

Family

ID=42060015

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0919245A BRPI0919245A2 (pt) 2008-09-24 2009-07-22 Vacina para malária

Country Status (5)

Country Link
US (1) US8501926B2 (pt)
EP (1) EP2331119A4 (pt)
AU (1) AU2009297127A1 (pt)
BR (1) BRPI0919245A2 (pt)
WO (1) WO2010036293A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220072115A1 (en) * 2018-11-07 2022-03-10 Rhode Island Hospital Malaria antigens on the surface of erythrocytes and merozoites and protective antibodies

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6333406B1 (en) * 1988-08-12 2001-12-25 Joseph W. Inselburg Gene encoding protein antigens of Plasmodium falciparum and uses therefor
US5798105A (en) * 1990-06-06 1998-08-25 University Of Nijmegan DNA encoding a plasmodium 16kD protein
AU1588092A (en) 1991-02-22 1992-09-15 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Transmission blocking vaccine against malaria
US5502168A (en) * 1991-10-24 1996-03-26 The Johns Hopkins University Monoclonal antibodies to a continuous and cross-reactive epitope and an isolated protein of a sexual stage of P. falciparum
US5527700A (en) 1992-07-10 1996-06-18 The United States Of America As Represented By The Department Of Health And Human Services Target antigens of transmission blocking antibodies for malaria parasites
NL9202026A (nl) * 1992-11-20 1994-06-16 Stichting Katholieke Univ Recombinant nuclëinezuur, daardoor gecodeerd polypeptide materiaal en daarop gebaseerd transmissie-blokkerend vaccin ter bestrijding van de malariaparasiet Plasmodium falciparum.
WO1994017187A1 (en) * 1993-01-29 1994-08-04 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services CLONING AND EXPRESSION OF PLASMODIUM FALCIPARUM TRANSMISSION-BLOCKING TARGET ANTIGEN, Pfs230
FR2744724B1 (fr) * 1996-02-14 2002-08-02 Pasteur Institut Proteine recombinante contenant un fragment c-terminal de la proteine msp-1 d'un plasmodium infectieux pour l'homme pour la production de vaccins anti-paludiques
DE19640817A1 (de) * 1996-10-02 1998-05-14 Hermann Prof Dr Bujard Rekombinantes Herstellungsverfahren für ein vollständiges Malaria-Antigen gp190/MSP 1
US7407658B2 (en) 1997-05-01 2008-08-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Vaccines for blocking transmission of plasmodium vivax
US7192934B1 (en) * 1997-05-01 2007-03-20 The United States Of America As Represented By The Department Of Health And Human Services Vaccines for blocking transmission of Plasmodium vivax
US20050096288A1 (en) * 1997-06-13 2005-05-05 Aragene, Inc. Lipoproteins as nucleic acid vectors
US6846481B1 (en) * 1999-02-04 2005-01-25 University Of Georgia Research Foundation, Inc. Recombinant expression of heterologous nucleic acids in protozoa
CZ303515B6 (cs) * 1999-04-19 2012-11-07 Smithkline Beecham Biologicals S. A. Adjuvantní prostredek
BRPI0203949B8 (pt) * 2001-01-24 2021-05-25 Univ Osaka Res Found For Microbial Diseases polipeptídeo se36, processo para purificação do polipeptídeo se36, vacina para malária, agente de diagnóstico para malária e fragmento de dna sintético
WO2003045304A2 (en) * 2001-09-26 2003-06-05 Mayo Foundation For Medical Education And Research Mutable vaccines
CA2480504A1 (en) * 2002-04-01 2003-10-16 Evelina Angov Method of designing synthetic nucleic acid sequences for optimal protein expression in a host cell
CN100360558C (zh) * 2002-06-11 2008-01-09 葛兰素史密丝克莱恩生物有限公司 免疫原性组合物
EP1569674B1 (en) 2002-11-12 2014-12-24 Walter Reed Army Institute of Research Expression, purification and uses of a plasmodium falciparum liver stage antigen 1 polypeptide
EP1573012B1 (en) * 2002-12-17 2011-11-30 Crucell Holland B.V. Recombinant viral-based malaria vaccines
US7550263B2 (en) * 2003-09-05 2009-06-23 Gtc Biotherapeutics, Inc. Method for the production of fusion proteins in transgenic mammal milk
GB0321615D0 (en) * 2003-09-15 2003-10-15 Glaxo Group Ltd Improvements in vaccination
US8273357B2 (en) * 2004-07-16 2012-09-25 Massachusetts Institute Of Technology Antigen-carbohydrate conjugates
US20060233789A1 (en) * 2004-09-24 2006-10-19 Cellfree Science Co., Ltd. Process for producing antigenic substance
WO2006124712A2 (en) * 2005-05-16 2006-11-23 Merck & Co., Inc. A method for improving the immunogenicity of plasmodium antigens
AU2007220988B2 (en) * 2006-02-28 2010-06-03 Vaxart, Inc Chimeric adenoviral vectors
AU2007276219B2 (en) * 2006-07-18 2013-10-03 Glaxosmithkline Biologicals S.A. Vaccines for malaria
CN101658533A (zh) * 2008-08-29 2010-03-03 首都医科大学宣武医院 抗肿瘤药物的干细胞递送

Also Published As

Publication number Publication date
EP2331119A4 (en) 2012-05-30
US20110171266A1 (en) 2011-07-14
AU2009297127A1 (en) 2010-04-01
US8501926B2 (en) 2013-08-06
WO2010036293A8 (en) 2010-06-03
WO2010036293A1 (en) 2010-04-01
EP2331119A1 (en) 2011-06-15

Similar Documents

Publication Publication Date Title
PH12014501835A1 (en) Novel adjuvant compositions
BR112015027280A8 (pt) nanocarreadores sintéticos tolerogênicos para reduzir ou prevenir anafilaxia em resposta a um antígeno não alergênico
CO6382140A2 (es) Composiciones de vacuna que comprenden una proteina de enlace del factor h mutada
EP3616716A3 (en) Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
MY197723A (en) Vaccine compositions for the prevention of dengue virus infection
MX340830B (es) Vacuna neumococica y usos de la misma.
EA201290956A1 (ru) Вакцина против вич
MX2015000446A (es) Composiciones de vacuna para la prevencion contra la infeccion por el virus del dengue.
BR112016015422A2 (pt) formulações de vacina de frasco único
WO2010151076A3 (ko) 폴리감마글루탐산-키토산 나노입자를 함유하는 면역보강제 조성물
MX2016016865A (es) Reduccion de infecciones en instalaciones de atencion medica usando composiciones fotocataliticas.
BRPI0919245A2 (pt) Vacina para malária
MA32305B1 (fr) Vaccin contre le virus vivant attenue inactive de la fievre catarrhale ovine
GB201112587D0 (en) Vaccine
ECSP099066A (es) Vacuna combinada estreptococica
BR112013023354A2 (pt) vacina para rinite equina
WO2009023308A3 (en) Genetically modified babesia parasites expressing protective tick antigens and uses thereof
MX2014009022A (es) Virus de influenza c y vacuna.
BR112012016314A2 (pt) "uso de antígenos de rhdococcus equi, composição, e, método para proteger um animal contra um distúrbio".
AU2010223786B2 (en) Auxotrophic, recombinant BCG strain Pasteur and use thereof for combating human infections caused by parasites
BRPI0713274A2 (pt) combinação de vacinas para a proteção de peixes contra a infecção estreptocócica, e, método para a preparação de uma combinação de vacinas
WO2009117736A3 (en) Avian virus vaccines and uses thereof
BR112013007308A2 (pt) vacina
PH12015500353A1 (en) Metadoxine for use in the treatment of liver diseases, and metadoxine extended release formulations
WO2009026375A3 (en) Spermicidal and microbicidal compositions

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2653 DE 09-11-2021 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.