BRPI0819845A2 - Ácidos nucleicos que se ligam à mcp-1 e uso dos mesmos - Google Patents

Ácidos nucleicos que se ligam à mcp-1 e uso dos mesmos

Info

Publication number
BRPI0819845A2
BRPI0819845A2 BRPI0819845-4A BRPI0819845A BRPI0819845A2 BR PI0819845 A2 BRPI0819845 A2 BR PI0819845A2 BR PI0819845 A BRPI0819845 A BR PI0819845A BR PI0819845 A2 BRPI0819845 A2 BR PI0819845A2
Authority
BR
Brazil
Prior art keywords
mcp
bind
nucleic acids
nucleic
acids
Prior art date
Application number
BRPI0819845-4A
Other languages
English (en)
Portuguese (pt)
Inventor
Werner Purschke
Florian Jarosch
Dirk Eulberg
Sven Klussmann
Klaus Buchner
Christian Maasch
Original Assignee
Noxxon Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Noxxon Pharma Ag filed Critical Noxxon Pharma Ag
Publication of BRPI0819845A2 publication Critical patent/BRPI0819845A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2320/00—Applications; Uses
    • C12N2320/30—Special therapeutic applications

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Transplantation (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
BRPI0819845-4A 2007-11-30 2008-11-29 Ácidos nucleicos que se ligam à mcp-1 e uso dos mesmos BRPI0819845A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07023267 2007-11-30
PCT/EP2008/010167 WO2009068318A1 (en) 2007-11-30 2008-11-29 Mcp-i binding nucleic acids and use thereof

Publications (1)

Publication Number Publication Date
BRPI0819845A2 true BRPI0819845A2 (pt) 2015-06-16

Family

ID=40415282

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0819845-4A BRPI0819845A2 (pt) 2007-11-30 2008-11-29 Ácidos nucleicos que se ligam à mcp-1 e uso dos mesmos

Country Status (12)

Country Link
US (2) US20100311816A1 (cg-RX-API-DMAC7.html)
EP (1) EP2229442A1 (cg-RX-API-DMAC7.html)
JP (1) JP5777341B2 (cg-RX-API-DMAC7.html)
KR (1) KR20100092463A (cg-RX-API-DMAC7.html)
CN (1) CN101878305A (cg-RX-API-DMAC7.html)
AU (1) AU2008329070B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0819845A2 (cg-RX-API-DMAC7.html)
CA (1) CA2707089A1 (cg-RX-API-DMAC7.html)
MX (1) MX2010005916A (cg-RX-API-DMAC7.html)
RU (1) RU2542973C2 (cg-RX-API-DMAC7.html)
WO (1) WO2009068318A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201002974B (cg-RX-API-DMAC7.html)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2397803T3 (es) 2006-02-14 2013-03-11 Noxxon Pharma Ag Ácidos nucleicos de unión a MCP-1
BRPI0819845A2 (pt) * 2007-11-30 2015-06-16 Noxxon Pharma Ag Ácidos nucleicos que se ligam à mcp-1 e uso dos mesmos
WO2012025251A1 (en) 2010-08-27 2012-03-01 Noxxon Pharma Ag Nucleic acids for treatment of chronic complications of diabetes
CN102621331B (zh) * 2012-04-05 2014-07-30 中国医学科学院病原生物学研究所 一种检测或辅助检测结核性胸膜炎的试剂盒
EP3065744B1 (en) * 2013-11-04 2021-04-21 Noxxon Pharma AG A ccl2 antagonist for use in treating proteinuria

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6670321B1 (en) * 1998-12-30 2003-12-30 The Children's Medical Center Corporation Prevention and treatment for retinal ischemia and edema
US20070026394A1 (en) * 2000-02-11 2007-02-01 Lawrence Blatt Modulation of gene expression associated with inflammation proliferation and neurite outgrowth using nucleic acid based technologies
WO2003035665A1 (de) * 2001-10-26 2003-05-01 Noxxon Pharma Ag Modifizierte l-nukleinsäure
EP1501929B1 (de) * 2002-05-06 2013-03-27 Noxxon Pharma AG Cgrp bindende nukleinsäuren
AU2003251681A1 (en) * 2002-08-01 2004-02-23 Noxxon Pharma Ag Ghrelin binding nucleic acids
CA2521950C (en) * 2003-04-15 2009-11-17 Merck & Co., Inc. Benzoxazinyl-amidocyclopentyl-heterocyclic modulators of chemokine receptors
EP1732571A4 (en) * 2004-03-05 2009-09-09 Archemix Corp CONTROLLED MODULATION OF PHARMACOKINETICS AND BIOLOGICAL DISTRIBUTION OF APTAMERIC THERAPY
US20060257359A1 (en) * 2005-02-28 2006-11-16 Cedric Francois Modifying macrophage phenotype for treatment of disease
US8367629B2 (en) * 2006-02-14 2013-02-05 Noxxon Pharma Ag MCP-1 binding nucleic acids and use thereof
ES2397803T3 (es) * 2006-02-14 2013-03-11 Noxxon Pharma Ag Ácidos nucleicos de unión a MCP-1
BRPI0819845A2 (pt) * 2007-11-30 2015-06-16 Noxxon Pharma Ag Ácidos nucleicos que se ligam à mcp-1 e uso dos mesmos

Also Published As

Publication number Publication date
JP2011504736A (ja) 2011-02-17
MX2010005916A (es) 2010-06-11
RU2010126662A (ru) 2012-01-10
RU2542973C2 (ru) 2015-02-27
WO2009068318A1 (en) 2009-06-04
US20100311816A1 (en) 2010-12-09
ZA201002974B (en) 2011-07-27
AU2008329070B2 (en) 2014-11-20
US20150141496A1 (en) 2015-05-21
EP2229442A1 (en) 2010-09-22
JP5777341B2 (ja) 2015-09-09
KR20100092463A (ko) 2010-08-20
CA2707089A1 (en) 2009-06-04
CN101878305A (zh) 2010-11-03
AU2008329070A1 (en) 2009-06-04

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law
B07D Technical examination (opinion) related to article 229 of industrial property law
B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)
B07E Notice of approval relating to section 229 industrial property law