BRPI0719918A2 - Tratamento para olho seco usando-se testosterona e progestagênio - Google Patents

Tratamento para olho seco usando-se testosterona e progestagênio

Info

Publication number
BRPI0719918A2
BRPI0719918A2 BRPI0719918-0A2A BRPI0719918A BRPI0719918A2 BR PI0719918 A2 BRPI0719918 A2 BR PI0719918A2 BR PI0719918 A BRPI0719918 A BR PI0719918A BR PI0719918 A2 BRPI0719918 A2 BR PI0719918A2
Authority
BR
Brazil
Prior art keywords
progestagen
testosterone
dry eye
eye treatment
treatment
Prior art date
Application number
BRPI0719918-0A2A
Other languages
English (en)
Portuguese (pt)
Inventor
Charles G Connor
Charles Haine
Original Assignee
Southern College Of Optometry
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Southern College Of Optometry filed Critical Southern College Of Optometry
Publication of BRPI0719918A2 publication Critical patent/BRPI0719918A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Eyeglasses (AREA)
BRPI0719918-0A2A 2006-12-05 2007-12-05 Tratamento para olho seco usando-se testosterona e progestagênio BRPI0719918A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/634,347 US20080132475A1 (en) 2006-12-05 2006-12-05 Treatment for dry eye
PCT/US2007/086517 WO2008070728A2 (en) 2006-12-05 2007-12-05 Treatment for dry eye using testosterone and progestagen

Publications (1)

Publication Number Publication Date
BRPI0719918A2 true BRPI0719918A2 (pt) 2014-03-04

Family

ID=39476533

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI0719918-0A2A BRPI0719918A2 (pt) 2006-12-05 2007-12-05 Tratamento para olho seco usando-se testosterona e progestagênio
BRPI0720172-9A BRPI0720172A2 (pt) 2006-12-05 2007-12-05 Tratamento para olho seco

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0720172-9A BRPI0720172A2 (pt) 2006-12-05 2007-12-05 Tratamento para olho seco

Country Status (12)

Country Link
US (3) US20080132475A1 (OSRAM)
EP (2) EP2101785A4 (OSRAM)
JP (2) JP2010511730A (OSRAM)
KR (2) KR20090104814A (OSRAM)
CN (2) CN101636164A (OSRAM)
AU (1) AU2009202711A1 (OSRAM)
BR (2) BRPI0719918A2 (OSRAM)
CA (2) CA2671698A1 (OSRAM)
EA (2) EA200900662A1 (OSRAM)
IL (1) IL199094A0 (OSRAM)
MX (2) MX2009005993A (OSRAM)
WO (2) WO2008070728A2 (OSRAM)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2008289552B2 (en) * 2007-08-16 2014-10-09 The Schepens Eye Research Institute, Inc. Therapeutic compositions for treatment of inflammation of ocular and adnexal tissues
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen
WO2010016042A1 (en) * 2008-08-05 2010-02-11 University College Cork, National University Of Ireland, Cork Treatment of retinal degeneration
AU2012209184B2 (en) 2011-01-26 2017-06-15 Allergan, Inc. Androgen composition for treating an opthalmic condition
BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
HUE046963T2 (hu) * 2012-07-27 2020-04-28 Glia Llc Készítmények és kezelés szembetegségekhez és rendellenességekhez
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CA2909490C (en) 2013-03-15 2021-07-13 Glia, Llc Cranial delivery of pharmaceuticals
RU2016143081A (ru) 2014-05-22 2018-06-26 Терапьютиксмд, Инк. Натуральные комбинированные гормонозаместительные составы и терапии
AU2015296609A1 (en) 2014-07-29 2016-12-22 Therapeuticsmd, Inc. Transdermal cream
US9504645B2 (en) * 2014-10-20 2016-11-29 Oyster Point Pharma, Inc. Pharmaceutical formulations for treating ocular conditions
US20180071313A1 (en) * 2015-04-03 2018-03-15 Santen Pharmaceutical Co., Ltd. Dry eye therapeutic agent comprising nandrolone or ester thereof or methenolone or ester thereof as an active ingredient
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
KR20180126582A (ko) 2016-04-01 2018-11-27 쎄러퓨틱스엠디, 인코퍼레이티드 스테로이드 호르몬 약제학적 조성물
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
IL265225B (en) 2016-09-07 2022-08-01 Glia Llc Treatment of symptoms related to neurodegenerative disorders through pharmacological dermal activation of cranial nerves
CA3157934A1 (en) * 2019-11-13 2021-05-20 Kenneth I. Sawyer Testosterone compositions
WO2023107796A1 (en) * 2021-12-11 2023-06-15 The Regents Of The University Of California Ophthalmic formulations for macular degeneration

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2861920A (en) * 1954-05-04 1958-11-25 Upjohn Co Therapeutic suspensions of steroids containing pvp and/or pva
JPS59184135A (ja) * 1983-04-04 1984-10-19 Teijin Ltd グリセリンピログルタミン酸エステル類を含有する医薬品組成物
US4617299A (en) * 1983-12-19 1986-10-14 Knepper Paul A Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension
DE3514724A1 (de) * 1985-04-24 1986-10-30 Albin F. Dr. 4200 Oberhausen Jereb Salbe zur verbeugung und behandlung von augen- und hauterkrankungen
US4914088A (en) * 1987-04-02 1990-04-03 Thomas Glonek Dry eye treatment solution and method
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
USRE34578E (en) * 1990-05-07 1994-04-05 Lubkin; Virginia Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application
ZA912797B (en) * 1990-05-29 1992-12-30 Boston Ocular Res Dry eye treatment process and solution
US5688765A (en) * 1992-04-21 1997-11-18 The Schepens Eye Research Institute, Inc. Ocular therapy in Sjogren's syndrome using topically applied androgensor TGF-β
WO1993020823A1 (en) * 1992-04-21 1993-10-28 The Schepens Eye Research Institute, Inc. Ocular androgen therapy in sjögren's syndrome
US6107289A (en) * 1992-04-21 2000-08-22 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens or TGF-β
US5958912A (en) * 1992-04-21 1999-09-28 The Schepens Eye Research Institute, Inc. Ocular therapy in keratoconjunctivitis sicca using topically applied androgens of TGF-β
US5366739A (en) * 1992-08-06 1994-11-22 Deo Corporation Method of ophthalmic drug delivery
ATE191641T1 (de) * 1992-08-28 2000-04-15 Pharmos Corp Emulsionen im submikron-bereich als vehikel zur arzneistoffverabreichung am auge
WO1997020578A1 (en) * 1995-12-04 1997-06-12 University Of Miami Non-preserved topical corticosteroid for treatment of dry eye, filamentary keratitis, and delayed tear clearance
CA2632790A1 (en) * 1996-07-22 1998-01-29 Renovo Limited Use of sex steroid function modulators to treat wounds and fibrotic disorders
PL335410A1 (en) * 1997-02-28 2000-04-25 Minnesota Mining & Mfg Medium for transcutaneous testosterone administration
US5869090A (en) * 1998-01-20 1999-02-09 Rosenbaum; Jerry Transdermal delivery of dehydroepiandrosterone
FR2774587B1 (fr) * 1998-02-09 2000-03-10 Oreal Utilisation d'une microdispersion de cire dans une composition cosmetique ou dermatologique
US6348210B1 (en) * 1998-11-13 2002-02-19 Alza Corporation Methods for transdermal drug administration
US6117446A (en) * 1999-01-26 2000-09-12 Place; Virgil A. Drug dosage unit for buccal administration of steroidal active agents
TR200200406T2 (tr) * 1999-06-11 2002-06-21 Watson Pharmaceuticals, Inc. Kadınlara oral olmayan yollarla androjenik steroidlerin uygulanması
WO2001041806A1 (en) * 1999-12-07 2001-06-14 Rohto Pharmaceutical Co., Ltd. Ophthalmic compositions
US6630175B1 (en) * 2000-06-29 2003-10-07 Johnson & Johnson Consumer Companies, Inc. Method of reducing eye irritation
WO2002055020A2 (en) * 2000-12-11 2002-07-18 Testocreme Llc Topical testosterone formulations and associated methods
US6659985B2 (en) * 2002-01-30 2003-12-09 Southern College Of Optometry Method to use transdermal administration of androgens to the adnexa of the eye
AU2003290776A1 (en) * 2002-11-15 2004-06-15 Panaseca, Inc. Methods and compositions for alleviating dry eyes
US20060111318A1 (en) * 2003-04-18 2006-05-25 Advanced Medicine Research Institute Agent for treating eye diseases
US6984628B2 (en) * 2003-07-15 2006-01-10 Allergan, Inc. Ophthalmic compositions comprising trefoil factor family peptides
US7960350B2 (en) * 2003-10-24 2011-06-14 Ader Enterprises, Inc. Composition and method for the treatment of eye disease
US20050202097A1 (en) * 2004-03-12 2005-09-15 Melbj Holdings, Llc, Florida Lubricant for the ocular surface
US20050234018A1 (en) * 2004-04-15 2005-10-20 Allergan, Inc. Drug delivery to the back of the eye
US20060110428A1 (en) * 2004-07-02 2006-05-25 Eugene Dejuan Methods and devices for the treatment of ocular conditions
AU2006213673A1 (en) * 2005-02-09 2006-08-17 Santen Pharmaceutical Co., Ltd. Formulations for ocular treatment
US20100016264A1 (en) * 2007-12-05 2010-01-21 Connor Charles G Treatment for dry eye using testosterone and progestagen

Also Published As

Publication number Publication date
KR20090104813A (ko) 2009-10-06
IL199094A0 (en) 2010-03-28
CN101636165A (zh) 2010-01-27
MX2009005993A (es) 2009-12-14
CA2671698A1 (en) 2008-06-12
EP2101785A4 (en) 2009-12-30
WO2008070726A3 (en) 2008-08-21
WO2008070728A3 (en) 2008-08-07
AU2009202711A1 (en) 2009-07-23
MX2009005994A (es) 2009-12-14
EA200900663A1 (ru) 2009-12-30
WO2008070726A2 (en) 2008-06-12
EA200900662A1 (ru) 2009-12-30
US20140113889A1 (en) 2014-04-24
JP2010511730A (ja) 2010-04-15
JP2010511729A (ja) 2010-04-15
CA2671769A1 (en) 2008-06-12
US20210008079A1 (en) 2021-01-14
KR20090104814A (ko) 2009-10-06
EP2124958A2 (en) 2009-12-02
WO2008070728A2 (en) 2008-06-12
US20080132475A1 (en) 2008-06-05
CN101636164A (zh) 2010-01-27
BRPI0720172A2 (pt) 2014-01-07
EP2101785A2 (en) 2009-09-23
EP2124958A4 (en) 2009-12-30

Similar Documents

Publication Publication Date Title
BRPI0719918A2 (pt) Tratamento para olho seco usando-se testosterona e progestagênio
NL301192I2 (nl) Finerenon en zijn zouten, solvaten en solvaten van de zouten daarvan
BRPI0819331A2 (pt) Métodos e composições para o tratamento do olho seco
BRPI0813553A2 (pt) composições farmacêuticas e métodos para tratamento de distúrbios do olho seco
BRPI0817082A2 (pt) Implantes lacrimais e métodos relacionados
BRPI0717389A2 (pt) Dispositivos e métodos para avanço de stent
BRPI0907890A2 (pt) Implantes lacrimais e métodos relacionados
BRPI0912290A2 (pt) detergentes para pele e mãos.
BRPI0809978A2 (pt) Dispositivos e métodos de dispensação de gotículas
BRPI0716300A2 (pt) Artigo e mistura
BRPI0921321A2 (pt) métodos para o tratamento de indwcções e tumores
BRPI0813725A2 (pt) Métodos e composições para tratamento de doenças
BRPI0821648A2 (pt) Método e dispositivo para pó desagregante
BRPI0813212A2 (pt) Métodos de tratamento de doenças e distúrbios mediados por serotonina
ATE484192T1 (de) Verfolgbarkeitsprozess und in dem prozess verwendete sicherheitselemente
CY2015013I2 (el) Αντι-μολυσματικες πυραμιδινες και χρησεις αυτων
BRPI0923760A2 (pt) artigos nanoestruturados e métodos para fabricação de artigos nanoestruturados
EP2331950A4 (en) NANOSTRUCTURED MICROELECTRODES AND BIODETING DEVICES INCLUDING THE SAME
BRPI0822064A2 (pt) Dispositivos de imageamento fotoacústico e métodos de imageamento
BRPI0819980A2 (pt) Conjunto e método de sutura
BRPI0907231A2 (pt) pirrolpirimidinas e pirrolpiridinas
EP2228480A4 (en) LAVANTE-DRYING MACHINE AND DEODORIZING DEVICE
IL206549A (en) A device for treating and using tinnitus
BRPI0919150A2 (pt) aplicadores de fluxo de ar e métodos de tratamento relacionados
BRPI0814330A2 (pt) métodos e kits cirúrgicos

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2277 DE 26/08/2014.