BRPI0716742A2 - Lactamas terapêuticas - Google Patents
Lactamas terapêuticasInfo
- Publication number
- BRPI0716742A2 BRPI0716742A2 BRPI0716742A BRPI0716742A2 BR PI0716742 A2 BRPI0716742 A2 BR PI0716742A2 BR PI0716742 A BRPI0716742 A BR PI0716742A BR PI0716742 A2 BRPI0716742 A2 BR PI0716742A2
- Authority
- BR
- Brazil
- Prior art keywords
- lactams
- therapeutic
- therapeutic lactams
- Prior art date
Links
- 150000003951 lactams Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US82210806P | 2006-08-11 | 2006-08-11 | |
| PCT/US2007/075615 WO2008021975A2 (en) | 2006-08-11 | 2007-08-09 | Therapeutic lactams |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0716742A2 true BRPI0716742A2 (pt) | 2015-03-24 |
Family
ID=38683367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0716742 BRPI0716742A2 (pt) | 2006-08-11 | 2007-08-09 | Lactamas terapêuticas |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7482475B2 (enExample) |
| EP (1) | EP2066660A2 (enExample) |
| JP (1) | JP2010500416A (enExample) |
| KR (1) | KR101422305B1 (enExample) |
| CN (1) | CN101522669B (enExample) |
| AU (1) | AU2007286177B2 (enExample) |
| BR (1) | BRPI0716742A2 (enExample) |
| CA (1) | CA2660608A1 (enExample) |
| MX (1) | MX2009001578A (enExample) |
| NZ (1) | NZ597866A (enExample) |
| WO (1) | WO2008021975A2 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7592364B2 (en) * | 2006-02-28 | 2009-09-22 | Allergan, Inc. | Substituted gamma lactams as therapeutic agents |
| EP1996546B1 (en) * | 2006-03-20 | 2014-11-26 | Allergan, Inc. | Substituted gamma lactams as prostaglandin ep2 agonists |
| WO2008021975A2 (en) * | 2006-08-11 | 2008-02-21 | Allergan, Inc. | Therapeutic lactams |
| US7589213B2 (en) * | 2007-04-27 | 2009-09-15 | Old David W | Therapeutic substituted lactams |
| US8440819B2 (en) * | 2008-02-22 | 2013-05-14 | Allergan, Inc. | Therapeutic substituted beta-lactams |
| CN102076681A (zh) * | 2008-04-24 | 2011-05-25 | 阿勒根公司 | 作为治疗剂的取代γ-内酰胺 |
| WO2014031581A1 (en) * | 2012-08-21 | 2014-02-27 | Allergan, Inc. | Process for the synthesis of substituted gamma lactams |
| US20150274658A1 (en) * | 2014-03-27 | 2015-10-01 | Allergan, Inc. | Therapeutic lactams |
| HK1249104A1 (zh) | 2015-03-13 | 2018-10-26 | Forma Therapeutics, Inc. | 作为HDAC8抑制剂的α-肉桂酰胺化合物和组合物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1991504A (en) * | 1928-09-12 | 1935-02-19 | American District Telegraph Co | Key-trapping valve lock for transmitter-supervised sprinkler systems |
| US5049577A (en) * | 1990-01-29 | 1991-09-17 | E. R. Squibb & Sons, Inc. | 2-pyrrolidone substituted dihydroxy alkanoic, alkenoic and alkynoic acids, compositions and HMG-CoA reductase inhibition therewith |
| US5902726A (en) * | 1994-12-23 | 1999-05-11 | Glaxo Wellcome Inc. | Activators of the nuclear orphan receptor peroxisome proliferator-activated receptor gamma |
| NZ535024A (en) * | 2002-03-05 | 2006-10-27 | Ono Pharmaceutical Co | 8-azaprostaglandin derivative compound and agent comprising the compound as active ingredient |
| AU2003258433A1 (en) | 2002-08-28 | 2004-03-19 | Merck Frosst Canada Ltd | Oxazolidin-2-one and thiazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of glaucoma |
| JP5128954B2 (ja) * | 2004-12-06 | 2013-01-23 | メルク セローノ ソシエテ アノニム | Ｄｐ１受容体アゴニストとして使用されるピロリジン−２−オン誘導体 |
| BRPI0609021A2 (pt) * | 2005-03-10 | 2010-01-12 | Allergan Inc | gama lactamas substituìdas, composição e uso das mesmas |
| EP1996546B1 (en) * | 2006-03-20 | 2014-11-26 | Allergan, Inc. | Substituted gamma lactams as prostaglandin ep2 agonists |
| WO2008021975A2 (en) * | 2006-08-11 | 2008-02-21 | Allergan, Inc. | Therapeutic lactams |
-
2007
- 2007-08-09 WO PCT/US2007/075615 patent/WO2008021975A2/en not_active Ceased
- 2007-08-09 AU AU2007286177A patent/AU2007286177B2/en not_active Ceased
- 2007-08-09 KR KR1020097004976A patent/KR101422305B1/ko not_active Expired - Fee Related
- 2007-08-09 NZ NZ597866A patent/NZ597866A/xx not_active IP Right Cessation
- 2007-08-09 MX MX2009001578A patent/MX2009001578A/es active IP Right Grant
- 2007-08-09 BR BRPI0716742 patent/BRPI0716742A2/pt not_active IP Right Cessation
- 2007-08-09 JP JP2009524741A patent/JP2010500416A/ja active Pending
- 2007-08-09 CN CN2007800369601A patent/CN101522669B/zh not_active Expired - Fee Related
- 2007-08-09 CA CA002660608A patent/CA2660608A1/en not_active Abandoned
- 2007-08-09 EP EP07840832A patent/EP2066660A2/en not_active Withdrawn
- 2007-08-09 US US11/836,655 patent/US7482475B2/en active Active
-
2008
- 2008-12-15 US US12/334,704 patent/US8686025B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| KR101422305B1 (ko) | 2014-07-22 |
| MX2009001578A (es) | 2009-02-19 |
| KR20090038937A (ko) | 2009-04-21 |
| CN101522669B (zh) | 2013-01-16 |
| WO2008021975A2 (en) | 2008-02-21 |
| US7482475B2 (en) | 2009-01-27 |
| NZ597866A (en) | 2013-08-30 |
| JP2010500416A (ja) | 2010-01-07 |
| EP2066660A2 (en) | 2009-06-10 |
| AU2007286177A1 (en) | 2008-02-21 |
| US8686025B2 (en) | 2014-04-01 |
| US20080039505A1 (en) | 2008-02-14 |
| CN101522669A (zh) | 2009-09-02 |
| CA2660608A1 (en) | 2008-02-21 |
| WO2008021975A3 (en) | 2008-07-10 |
| AU2007286177B2 (en) | 2012-06-14 |
| US20090099249A1 (en) | 2009-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 5A, 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2329 DE 25-08-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |