BRPI0716397A2 - mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero. - Google Patents

mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero.

Info

Publication number
BRPI0716397A2
BRPI0716397A2 BRPI0716397-5A2A BRPI0716397A BRPI0716397A2 BR PI0716397 A2 BRPI0716397 A2 BR PI0716397A2 BR PI0716397 A BRPI0716397 A BR PI0716397A BR PI0716397 A2 BRPI0716397 A2 BR PI0716397A2
Authority
BR
Brazil
Prior art keywords
promote osteogenesis
methods
mammalian cell
identify agents
osteogenesis
Prior art date
Application number
BRPI0716397-5A2A
Other languages
English (en)
Inventor
Yuanxiang Zhao
Sheng Ding
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of BRPI0716397A2 publication Critical patent/BRPI0716397A2/pt

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5073—Stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
BRPI0716397-5A2A 2006-08-11 2007-08-10 mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero. BRPI0716397A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US82218406P 2006-08-11 2006-08-11
US11/836,512 US7601501B2 (en) 2006-08-11 2007-08-09 Controlling osteogenesis by inhibition of osteogenic suppressors
PCT/US2007/017797 WO2008019159A2 (en) 2006-08-11 2007-08-10 Controlling osteogenesis by inhibition of osteogenic suppressors

Publications (1)

Publication Number Publication Date
BRPI0716397A2 true BRPI0716397A2 (pt) 2013-09-17

Family

ID=39033527

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0716397-5A2A BRPI0716397A2 (pt) 2006-08-11 2007-08-10 mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero.

Country Status (11)

Country Link
US (2) US7601501B2 (pt)
EP (1) EP2049158A4 (pt)
JP (1) JP2010500567A (pt)
KR (1) KR20090047508A (pt)
AU (1) AU2007281931A1 (pt)
BR (1) BRPI0716397A2 (pt)
CA (1) CA2659437A1 (pt)
IL (1) IL196760A0 (pt)
MX (1) MX2009001372A (pt)
RU (1) RU2009108662A (pt)
WO (1) WO2008019159A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9034299B2 (en) 2007-08-03 2015-05-19 Cornell University ATF4 inhibitors and their use for neural protection, repair, regeneration, and plasticity
KR20160015403A (ko) * 2009-07-14 2016-02-12 더 스크립스 리서치 인스티튜트 중간엽 줄기 세포 분화
EP2380595A1 (en) 2010-04-19 2011-10-26 Nlife Therapeutics S.L. Compositions and methods for selective delivery of oligonucleotide molecules to specific neuron types
ES2856091T3 (es) 2011-09-14 2021-09-27 Univ Northwestern Nanoconjugados capaces de atravesar la barrera hematoencefálica
WO2017053963A1 (en) 2015-09-25 2017-03-30 Cedars-Sinal Medical Center A method effective to modulate expression of t-box protein 4 (tbx4) for reducing progression of lung fibrosis after a lung injury
WO2019070908A1 (en) 2017-10-03 2019-04-11 Cedars-Sinai Medical Center METHODS OF TARGETING THE PD1 PATHWAY OF THE IMMUNE CONTROL POINT FOR THE TREATMENT OF PULMONARY FIBROSIS
WO2020132521A1 (en) * 2018-12-20 2020-06-25 Praxis Precision Medicines, Inc. Compositions and methods for the treatment of kcnt1 related disorders
PE20220168A1 (es) * 2019-03-15 2022-01-28 Ionis Pharmaceuticals Inc Compuestos y metodos para reducir la expresion de kcnt1
JP2022535717A (ja) * 2019-05-24 2022-08-10 エンピリコ インク． アンジオポエチン様７（ａｎｇｐｔｌ７）関連疾患の処置
EP4061945A1 (en) * 2019-11-22 2022-09-28 Alnylam Pharmaceuticals, Inc. Ataxin3 (atxn3) rnai agent compositions and methods of use thereof
US20230416754A1 (en) * 2020-11-23 2023-12-28 Phyzat Biopharmaceuticals, Lda Sina molecules, methods of production and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994006438A1 (en) 1992-09-11 1994-03-31 The Regents Of The University Of California Adenosine analogues and method of increasing adenosine release
CA2440747A1 (en) * 2001-03-15 2002-09-26 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2003064470A2 (en) * 2002-02-01 2003-08-07 Bayer Healthcare Ag Regulation of human calcium-activated potassium channel protein
EP1556129A4 (en) 2002-10-15 2011-02-09 Irm Llc COMPOSITIONS AND METHODS FOR INDUCING OSTEOGENESIS
US20040241720A1 (en) * 2003-02-26 2004-12-02 Salkoff Lawrence B. Sodium activated potassium ion channel for therapeutic drug screening
ES2398239T3 (es) 2003-11-10 2013-03-14 The Scripps Research Institute Composiciones y procedimientos para inducir la desdiferenciación celular
US20060020036A1 (en) * 2004-06-24 2006-01-26 Luc Van Rompaey Methods and compositions to promote bone homestasis
US20060019907A1 (en) 2004-07-12 2006-01-26 Research Development Foundation Guggulsterone: an inhibitor of nuclear factor - kappaB and IkappaBalpha kinase activation and uses thereof

Also Published As

Publication number Publication date
EP2049158A4 (en) 2010-04-07
WO2008019159A2 (en) 2008-02-14
US20080038202A1 (en) 2008-02-14
KR20090047508A (ko) 2009-05-12
MX2009001372A (es) 2009-02-13
RU2009108662A (ru) 2010-09-20
AU2007281931A1 (en) 2008-02-14
US7601501B2 (en) 2009-10-13
EP2049158A2 (en) 2009-04-22
IL196760A0 (en) 2011-08-01
WO2008019159A3 (en) 2009-04-16
US20100184113A1 (en) 2010-07-22
CA2659437A1 (en) 2008-02-14
JP2010500567A (ja) 2010-01-07

Similar Documents

Publication Publication Date Title
BRPI0716397A2 (pt) mÉtodos para identificar agentes que promovem a osteogÊnese e para promover a osteogÊnese em uma cÉlula de mamÍfero.
BRPI0813710A2 (pt) Enzimas que produzem acetil-coa em levedura
BRPI0809655A2 (pt) Método para tratar uma condição em um mamífero, composição farmacêutica, e, kit
BRPI0917475A2 (pt) caralisador que compreende uma zeólita izm-2 e pelo menos um metal e sua utilização em tranformação de hidrocarbonetos
BRPI0916630A2 (pt) composições para uso em construção e processo de aplicação das mesmas
BRPI0717068A2 (pt) instruÇço e làgica para processar cadeias de texto.
BRPI0908177A2 (pt) compósito elástico e método para produzir o mesmo
BRPI0813463A2 (pt) Aperfeiçoamento em membros estruturais compósitos alongados
DK2064333T3 (da) Suppressor-trna-transkription i hvirveldyrceller
BRPI0918632A2 (pt) dispositivo de separação com dupla transmissão e método de reduzir a formação de roscas em um dispositivo de separação.
BR112012005778A2 (pt) método e sistema para simulação em uma subestação
DK2125069T3 (da) Indretning til stof- og eller energiudveksling
BR112013014857A2 (pt) processo para a frezagem de uma reentrância em uma peça de trabalho e peça de trabalho com uma reentrância.
DK2274430T3 (da) Nerveregenererende celler med ændringer i dna-methylering
FI20095897A (fi) Menetelmä ja laitteisto jätekuilussa
BRPI0913136A2 (pt) método para produzir uma peça e peça.
FI20060347A (fi) Lujitettu puulevy ja menetelmä sen valmistamiseksi
BRPI0909689A2 (pt) dispositivo de autoendereçamento em uma fonte comum e estrutura de comunicação de barramento e método para sua realização
BRPI0814837A2 (pt) parafuso, método de substituição de um parafuso em uma dobradiça, kit, sistema para orientar um parafuso em uma dobradiça
BRPI0921012A2 (pt) inserto e cortador que pode ser montado com o inserto.
BRPI0816722A2 (pt) Conexão para o uso com tubulações de metal em uma jaqueta e conexão acoplada a tubulações de metal em uma jaqueta
BRPI0907357A2 (pt) painéis incluindo componentes ronováveis e métodos para fabricação
BRPI0722063A2 (pt) Processo e dispositivo para determinação de populações menores de célula em populações de células heterogêneas
DE602006016400D1 (de) Damit
DK2315899T3 (da) System forsynet med paneler og fremgangsmåde

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]