BRPI0701266A - fornecimento de enxertos vasculares com um princìpio ativo - Google Patents

fornecimento de enxertos vasculares com um princìpio ativo

Info

Publication number
BRPI0701266A
BRPI0701266A BRPI0701266-7A BRPI0701266A BRPI0701266A BR PI0701266 A BRPI0701266 A BR PI0701266A BR PI0701266 A BRPI0701266 A BR PI0701266A BR PI0701266 A BRPI0701266 A BR PI0701266A
Authority
BR
Brazil
Prior art keywords
palmitate
laurate
tobramycin
gentamicin
myristate
Prior art date
Application number
BRPI0701266-7A
Other languages
English (en)
Inventor
Klaus-Dieter Kuehn
Matthias Schnabelrauch
Sebastian Vogt
Original Assignee
Heraeus Kulzer Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Heraeus Kulzer Gmbh filed Critical Heraeus Kulzer Gmbh
Publication of BRPI0701266A publication Critical patent/BRPI0701266A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • A61L33/0041—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate characterised by the choice of an antithrombatic agent other than heparin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/45—Mixtures of two or more drugs, e.g. synergistic mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Materials Engineering (AREA)
  • Hematology (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Prostheses (AREA)
  • Saccharide Compounds (AREA)

Abstract

FORNECIMENTO DE ENXERTOS VASCULARES COM UM PRINCìPIO ATIVO. A presente invenção refere-se a uma ou mais substâncias do grupo que consiste em palmitato de gentamicina, miristato de gentamicina, laurato de gentamicina, palmitato de tobramicina, miristato de tobramicina, laurato de tobramicina, palmitato de amicacina, miristato de amicacina, laurato de amicacina, palmitato de vancomicina, laurato de vancomicina e miristato de vancomicina, são adequadas para fornecer enxertos vasculares com um princípio antitrombogenicamente ativo. O método apropriado para fornecer enxertos vasculares com um principio antitrombogenicamente ativo compreende particularmente as seguintes etapas de imersão do corpo do enxerto A em uma solução alcoólica ou uma solução alcoólica com um solvente rapidamente volátil, tal como clorofórmio, de um membro do grupo que consiste em palmitato de gentamicina, miristato de gentamicina, laurato de gentamicina, palmitato de tobramicina, miristato de tobramicina, laurato de tobramicina, palmitato de amicacina, miristato de amicacina, laurato de amicacina, palmitato de vancomicina e miristato de vancomicina, ou de pulverização da dita solução sobre o dito corpo do enxerto e de B vaporização do dito solvente alcoólico.
BRPI0701266-7A 2006-04-06 2007-04-04 fornecimento de enxertos vasculares com um princìpio ativo BRPI0701266A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102006016598A DE102006016598A1 (de) 2006-04-06 2006-04-06 Beschichtete Vaskulärimplantate

Publications (1)

Publication Number Publication Date
BRPI0701266A true BRPI0701266A (pt) 2008-07-15

Family

ID=38462244

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0701266-7A BRPI0701266A (pt) 2006-04-06 2007-04-04 fornecimento de enxertos vasculares com um princìpio ativo

Country Status (9)

Country Link
US (1) US20070264304A1 (pt)
EP (1) EP1842566A3 (pt)
JP (1) JP2007275598A (pt)
CN (1) CN101049520B (pt)
AU (1) AU2007201541B2 (pt)
BR (1) BRPI0701266A (pt)
CA (1) CA2582011C (pt)
DE (1) DE102006016598A1 (pt)
ZA (1) ZA200702820B (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9492374B2 (en) 2015-03-25 2016-11-15 Jose Rafael Salinas Andrade Composition and method for treatment of ulcers

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879135A (en) * 1984-07-23 1989-11-07 University Of Medicine And Dentistry Of New Jersey Drug bonded prosthesis and process for producing same
US4612337A (en) * 1985-05-30 1986-09-16 The Trustees Of Columbia University In The City Of New York Method for preparing infection-resistant materials
US4895566A (en) * 1986-07-25 1990-01-23 C. R. Bard, Inc. Coating medical devices with cationic antibiotics
US5019096A (en) * 1988-02-11 1991-05-28 Trustees Of Columbia University In The City Of New York Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same
JP3398415B2 (ja) * 1993-04-09 2003-04-21 テルモ株式会社 抗血栓性カテーテル
DE4314871A1 (de) * 1993-05-05 1994-11-10 Merck Patent Gmbh Lösungsmittel für ein schwerlösliches Gentamicin-Salz
DE4404018A1 (de) * 1994-02-09 1995-08-10 Merck Patent Gmbh Protrahiert freisetzende Darreichungsformen enthaltend Clindamycin-Palmitat
US5714359A (en) * 1995-10-12 1998-02-03 The University Of Akron Apparatus and method for electrostatic endothelial cell seeding in a vascular prosthesis
US6306165B1 (en) * 1996-09-13 2001-10-23 Meadox Medicals ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin
JP4347927B2 (ja) * 1998-08-24 2009-10-21 川澄化学工業株式会社 抗血栓性医療用具の製造方法
JP4937451B2 (ja) * 1998-09-14 2012-05-23 川澄化学工業株式会社 血管内ステント
AU2599501A (en) * 1999-12-29 2001-07-09 Advanced Cardiovascular Systems Inc. Device and active component for inhibiting formation of thrombus-inflammatory cell matrix
WO2001049338A1 (en) * 1999-12-30 2001-07-12 Li Wei Pin Controlled delivery of therapeutic agents by insertable medical devices
EP1842569A3 (de) * 2001-02-16 2010-03-03 Abbott Laboratories Vascular Enterprises Limited Implantate mit FK506
IS6390A (is) * 2001-08-31 2003-03-03 Heraeus Kulzer Gmbh & Co. Kg Reynsla af sýklalyfjahúðun skrokka sem í eru örholrými, þannig húðuðum skrokkum og einnig af notkunþeirra
DE10142464A1 (de) * 2001-08-31 2003-03-27 Heraeus Kulzer Gmbh & Co Kg Verfahren zur antibiotischen Beschichtung von nichtmetallischen Körpern mit interkonnektierenden Mikrohohlräumen sowie nichtmetallischer Körper und seine Verwendung
DE10227935B4 (de) * 2002-06-21 2007-10-04 Heraeus Kulzer Gmbh Verfahren zur Herstellung einer antibiotische Beschichtung von porösen Körpern sowie Verwendung
DE10318991A1 (de) * 2003-04-25 2004-11-18 Heraeus Kulzer Gmbh & Co. Kg Poröser Körper mit antibiotischer Beschichtung, Verfahren zur Herstellung sowie Verwendung
US7563780B1 (en) * 2004-06-18 2009-07-21 Advanced Cardiovascular Systems, Inc. Heparin prodrugs and drug delivery stents formed therefrom
DE102004060666B3 (de) * 2004-12-15 2006-03-30 Heraeus Kulzer Gmbh Antibiotikum/Antibiotika enthaltendes Knochenersatzmaterial mit retardierender Wirkstofffreisetzung
DE102005002703C5 (de) * 2005-01-19 2013-07-04 Heraeus Kulzer Gmbh Antibiotische Beschichtung von Implantaten sowie Verfahren zur antibiotischen Beschichtung
ATE551992T1 (de) * 2005-05-27 2012-04-15 Royer Biomedical Inc Bioresorbierbare polymermatrizes und verfahren zu ihrer herstellung und verwendung

Also Published As

Publication number Publication date
AU2007201541B2 (en) 2009-11-12
CA2582011A1 (en) 2007-10-06
AU2007201541A1 (en) 2007-10-25
EP1842566A3 (de) 2007-11-28
US20070264304A1 (en) 2007-11-15
ZA200702820B (en) 2008-08-27
CA2582011C (en) 2011-06-07
CN101049520B (zh) 2011-11-09
JP2007275598A (ja) 2007-10-25
EP1842566A2 (de) 2007-10-10
DE102006016598A1 (de) 2007-11-15
CN101049520A (zh) 2007-10-10

Similar Documents

Publication Publication Date Title
UY31673A1 (es) "derivados heterocíclicos de urea y métodos de uso de los mismos-211"
EP2231761A4 (en) QUATERNARY AMMONIUM POLYMERS DISINFECTANTS SOLUBLE IN ALCOHOL
BRPI0912230A2 (pt) Método para encapsular agentes biologicamente ativos em um carreador particulado, carreador particulado, e, composição farmacêutica
AR061483A1 (es) Combinaciones de agentes de control biologico con un revestimiento insecticida de las semillas
BRPI0907591A2 (pt) Compostos e composição farmacêutica como moduladores de atividade de gpr119, método in vitro para modulação da atividade de gpr119 e usos do referido composto, seus sais farmaceuticamente aceitáveis ou suas composições farmacêuticas.
EA033311B1 (ru) Производные бензоксаборола в качестве антибактериальных средств
AR047928A1 (es) Derivados de tetrahidropiridoindol
BR112012023638A2 (pt) Sistema de entrega, composição cosmética, farmacêutica e/ou alimentar e uso da composição cosmética, farmacêutica e/ou alimentar
WO2007143726A3 (en) Methods and compositons for tissue repair
CL2011000186A1 (es) Metodos para eliminar o prevenir el crecimiento de un microbio en un sustrato mediante la aplicacion de compuestos derivados de tetrakis (n-alquilpiridinio)- porfirina; composicion topica que comprende dicho compuesto; y metodo para prevenir y tratar una infeccion de la piel en un sujeto.
BR112014000178A2 (pt) composições tópicas
BR112012015682A2 (pt) composição transportadora.
BRPI0516077A (pt) composições antimicrobianas compreendendo um agente natural selecionado de ácido gálico, eucalipotol, naringina, um composto de ácido jasmÈnico e qualquer combinação destes
CL2011000729A1 (es) Compuestos derivados de metanopirazolo[3,4-e][1,3]diazepin; procedimiento de preparacion; composicion farmaceutica que los comprende; y su uso en el tratamiento de infecciones bacterianas.
BR112012029506A2 (pt) composição de perfume e usos destas
CL2008002984A1 (es) Composicion farmaceutica que comprende micofenolato sodico y su uso para el tratamiento y/o prevencion en enfermedades autoinmunes tales como el rechazo de aloinjertos o xenoinjertos de organos, celulas o tejidos y como antiinflamatorio.
CL2009002129A1 (es) Derivados carboxiamida de lantibioticos; proceso de preparacion de dichos lantibioticos; composicion farmaceutica que lo contiene; utiles en el tratamiento de infecciones bacterianas.
AR051144A1 (es) Procedimiento para formar atorvastatina amorfa
WO2005094265A3 (en) Self assembling activation agents targeted using active drug release
BRPI0511258A (pt) composições de fator de transferência encapsulado e métodos de uso
WO2010151879A9 (en) Photolabile compounds
WO2010009904A3 (de) Verfahren zur erzeugung einer bioaktiven oberfläche auf dem ballon eines ballonkatheters
BRPI0701266A (pt) fornecimento de enxertos vasculares com um princìpio ativo
WO2008105808A3 (en) FORMULATIONS OF RADIOPROTECTIVE α, β UNSATURATED ARYL SULFONES
PL2046813T3 (pl) Pochodne metotreksatu wiążące proteiny oraz leki zawierające te pochodne

Legal Events

Date Code Title Description
B03A Publication of a patent application or of a certificate of addition of invention [chapter 3.1 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: HERAEUS MEDICAL GMBH (DE)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2384 DE 13-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B07G Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette]