BRPI0613164A2 - anticorpos anti mcp-1, composições, métodos e usos - Google Patents
anticorpos anti mcp-1, composições, métodos e usos Download PDFInfo
- Publication number
- BRPI0613164A2 BRPI0613164A2 BRPI0613164-6A BRPI0613164A BRPI0613164A2 BR PI0613164 A2 BRPI0613164 A2 BR PI0613164A2 BR PI0613164 A BRPI0613164 A BR PI0613164A BR PI0613164 A2 BRPI0613164 A2 BR PI0613164A2
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- Prior art keywords
- mcp
- antibody
- human
- drug
- cells
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
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| US68262005P | 2005-05-19 | 2005-05-19 | |
| US68265405P | 2005-05-19 | 2005-05-19 | |
| US60/682,620 | 2005-05-19 | ||
| US60/682,654 | 2005-05-19 | ||
| PCT/US2006/019627 WO2006125202A2 (en) | 2005-05-19 | 2006-05-19 | Anti- mcp-1 antibodies, compositions, methods and uses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0613164A2 true BRPI0613164A2 (pt) | 2010-12-21 |
Family
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| BRPI0613164-6A BRPI0613164A2 (pt) | 2005-05-19 | 2006-05-19 | anticorpos anti mcp-1, composições, métodos e usos |
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| BR (1) | BRPI0613164A2 (cg-RX-API-DMAC7.html) |
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| CR (1) | CR9606A (cg-RX-API-DMAC7.html) |
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| ES (1) | ES2438193T3 (cg-RX-API-DMAC7.html) |
| IL (1) | IL187459A0 (cg-RX-API-DMAC7.html) |
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| NO (1) | NO20076563L (cg-RX-API-DMAC7.html) |
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| ZA (1) | ZA200711073B (cg-RX-API-DMAC7.html) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2008055945A1 (en) | 2006-11-09 | 2008-05-15 | Probiodrug Ag | 3-hydr0xy-1,5-dihydr0-pyrr0l-2-one derivatives as inhibitors of glutaminyl cyclase for the treatment of ulcer, cancer and other diseases |
| DK2091948T3 (da) | 2006-11-30 | 2012-07-23 | Probiodrug Ag | Nye inhibitorer af glutaminylcyclase |
| EP2481408A3 (en) | 2007-03-01 | 2013-01-09 | Probiodrug AG | New use of glutaminyl cyclase inhibitors |
| DK2142514T3 (da) | 2007-04-18 | 2015-03-23 | Probiodrug Ag | Thioureaderivater som glutaminylcyclase-inhibitorer |
| JP2011517548A (ja) * | 2007-06-29 | 2011-06-16 | セントコア・オーソ・バイオテツク・インコーポレーテツド | 抗mcp−1抗体、組成物、方法及び使用 |
| ES2533493T3 (es) * | 2008-08-20 | 2015-04-10 | Probiodrug Ag | Anticuerpos dirigidos contra la proteína 1 quimioatrayente de monocitos (MCP-1 N1pE) de piroglutamato |
| US8486940B2 (en) | 2009-09-11 | 2013-07-16 | Probiodrug Ag | Inhibitors |
| WO2011107530A2 (en) | 2010-03-03 | 2011-09-09 | Probiodrug Ag | Novel inhibitors |
| ES2481823T3 (es) | 2010-03-10 | 2014-07-31 | Probiodrug Ag | Inhibidores heterocíclicos de glutaminil ciclasa (QC, EC 2.3.2.5) |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| US8530670B2 (en) | 2011-03-16 | 2013-09-10 | Probiodrug Ag | Inhibitors |
| AU2013266340A1 (en) * | 2012-05-22 | 2014-12-04 | Shire Human Genetic Therapies, Inc. | Anti-CCL2 antibodies for treatment of scleroderma |
| EP2727944A1 (en) * | 2012-10-30 | 2014-05-07 | Universitätsklinikum Regensburg | Depletion of CCR2-positive monocytes for the treatment of inflammatory conditions in the gastrointestinal system |
| WO2015126898A1 (en) | 2014-02-18 | 2015-08-27 | Dignity Health | Lkb1 related diagnostics and treatments of cancer |
| EP3613435A1 (en) | 2015-01-28 | 2020-02-26 | Universite De Bordeaux | Chemokine receptor cxcr4 inhibitors for treating and/or preventing chronic obstructive pulmonary disease |
| WO2018014111A1 (en) | 2016-06-22 | 2018-01-25 | Harless William Warren | Cancer treatment and metastasis inhibition using an anti-cancer stem cell agent in combination with a neul sialidase inhibitor or a cytokine inhibitor after primary cancer treatment |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
| CA3135694A1 (en) | 2019-04-17 | 2020-10-22 | Hiroshima University | Therapeutic agent for urological cancer which is characterized by being administered with il-6 inhibitor and ccr2 inhibitor in combination |
| PE20221661A1 (es) | 2019-12-18 | 2022-10-26 | Hoffmann La Roche | Anticuerpos anti-ccl2 biespecificos |
| CN112358547A (zh) * | 2020-09-30 | 2021-02-12 | 浙江大学 | 抗人cxcl-2单克隆抗体3-d3及其编码基因和应用 |
| CN114990073A (zh) * | 2022-05-27 | 2022-09-02 | 河南农业大学 | 一种抗猪ccl2蛋白的单克隆抗体及其制备方法和应用 |
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| GB2183662B (en) | 1985-04-01 | 1989-01-25 | Celltech Ltd | Transformed myeloma cell-line and a process for the expression of a gene coding for a eukaryotic polypeptide employing same |
| GB8601597D0 (en) | 1986-01-23 | 1986-02-26 | Wilson R H | Nucleotide sequences |
| GB8717430D0 (en) | 1987-07-23 | 1987-08-26 | Celltech Ltd | Recombinant dna product |
| ATE102631T1 (de) | 1988-11-11 | 1994-03-15 | Medical Res Council | Klonierung von immunglobulin sequenzen aus den variabelen domaenen. |
| US5266491A (en) | 1989-03-14 | 1993-11-30 | Mochida Pharmaceutical Co., Ltd. | DNA fragment and expression plasmid containing the DNA fragment |
| US5427908A (en) | 1990-05-01 | 1995-06-27 | Affymax Technologies N.V. | Recombinant library screening methods |
| JPH05507700A (ja) | 1990-06-01 | 1993-11-04 | カイロン コーポレイション | 生物学的活性分子を同定するための組成物及び方法 |
| US5723286A (en) | 1990-06-20 | 1998-03-03 | Affymax Technologies N.V. | Peptide library and screening systems |
| WO1992005258A1 (en) | 1990-09-20 | 1992-04-02 | La Trobe University | Gene encoding barley enzyme |
| US5270170A (en) | 1991-10-16 | 1993-12-14 | Affymax Technologies N.V. | Peptide library and screening method |
| DE4436420C5 (de) | 1994-10-12 | 2009-04-02 | Daimler Ag | Mittelkonsole für ein Kraftfahrzeug |
| US6019968A (en) | 1995-04-14 | 2000-02-01 | Inhale Therapeutic Systems, Inc. | Dispersible antibody compositions and methods for their preparation and use |
| JP2001517692A (ja) | 1997-09-29 | 2001-10-09 | インヘール セラピューティック システムズ, インコーポレイテッド | ネブライザにおける使用のための安定化調製物 |
| GB0016138D0 (en) * | 2000-06-30 | 2000-08-23 | Novartis Ag | Organic compounds |
| IE20020532A1 (en) | 2001-06-27 | 2003-03-05 | Salviac Ltd | A Catheter |
| ATE517855T1 (de) * | 2001-11-30 | 2011-08-15 | Biogen Idec Inc | Antikörper gegen chemotaktische monozytenproteine |
| RU2339647C2 (ru) * | 2002-08-19 | 2008-11-27 | Астразенека Аб | Антитела против моноцитарного хемоаттрактантного белка-1 (мср-1) и их применение |
| WO2004024921A1 (ja) * | 2002-09-12 | 2004-03-25 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | ヒト抗ヒトmcp−1抗体及び該抗体フラグメント |
| AU2005214382B2 (en) | 2004-02-19 | 2011-08-04 | Genentech, Inc. | CDR-repaired antibodies |
| EP1784425A4 (en) * | 2004-06-30 | 2009-02-18 | Centocor Inc | ANTI-MCP-1 ANTIBODIES, COMPOSITIONS, METHODS AND USES |
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- 2006-05-18 TW TW095117600A patent/TW200716174A/zh unknown
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- 2006-05-18 PE PE2010000028A patent/PE20110071A1/es not_active Application Discontinuation
- 2006-05-19 EA EA200702532A patent/EA014229B1/ru not_active IP Right Cessation
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- 2007-12-18 ZA ZA200711073A patent/ZA200711073B/xx unknown
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2010
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| EP1888114A2 (en) | 2008-02-20 |
| ZA200711073B (en) | 2009-09-30 |
| EP1888114B1 (en) | 2013-09-18 |
| ES2438193T3 (es) | 2014-01-16 |
| NO20076563L (no) | 2008-02-05 |
| CA2609349A1 (en) | 2006-11-23 |
| NZ563516A (en) | 2011-04-29 |
| CA2609349C (en) | 2012-10-30 |
| CN101511869A (zh) | 2009-08-19 |
| TW200716174A (en) | 2007-05-01 |
| PE20061444A1 (es) | 2007-01-15 |
| KR100977823B1 (ko) | 2010-08-25 |
| AU2010202813A1 (en) | 2010-07-22 |
| MX2007014610A (es) | 2008-04-14 |
| EP1888114A4 (en) | 2010-02-24 |
| CR9606A (es) | 2010-08-18 |
| JP2008546374A (ja) | 2008-12-25 |
| JP4975020B2 (ja) | 2012-07-11 |
| EA200702532A1 (ru) | 2008-06-30 |
| PA8675801A1 (es) | 2006-12-07 |
| AU2006247034B2 (en) | 2010-12-02 |
| AU2006247034A1 (en) | 2006-11-23 |
| AU2010202813B2 (en) | 2011-11-03 |
| WO2006125202A2 (en) | 2006-11-23 |
| EA014229B1 (ru) | 2010-10-29 |
| KR20080012968A (ko) | 2008-02-12 |
| WO2006125202A3 (en) | 2009-05-07 |
| CN101511869B (zh) | 2012-12-12 |
| IL187459A0 (en) | 2008-03-20 |
| AR053470A1 (es) | 2007-05-09 |
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Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2516 DE 26-03-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |