BRPI0608217A2 - método para síntese de rotulação de complexo de gálio radiorrotulado, complexo de gálio radiorrotulado, e, método para formação de imagem de superexpressão de egfr em tumores - Google Patents

método para síntese de rotulação de complexo de gálio radiorrotulado, complexo de gálio radiorrotulado, e, método para formação de imagem de superexpressão de egfr em tumores

Info

Publication number
BRPI0608217A2
BRPI0608217A2 BRPI0608217A BRPI0608217A BRPI0608217A2 BR PI0608217 A2 BRPI0608217 A2 BR PI0608217A2 BR PI0608217 A BRPI0608217 A BR PI0608217A BR PI0608217 A BRPI0608217 A BR PI0608217A BR PI0608217 A2 BRPI0608217 A2 BR PI0608217A2
Authority
BR
Brazil
Prior art keywords
gallium complex
radiolabelled
radiolabelled gallium
tumors
synthesis
Prior art date
Application number
BRPI0608217A
Other languages
English (en)
Inventor
Asa Liljegren Sundberg
Bengt Langstrom
Irina Velikyan
Vladimir Tolmachev
Original Assignee
Ge Healthcare Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ge Healthcare Ltd filed Critical Ge Healthcare Ltd
Publication of BRPI0608217A2 publication Critical patent/BRPI0608217A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BRPI0608217A 2005-02-22 2006-02-21 método para síntese de rotulação de complexo de gálio radiorrotulado, complexo de gálio radiorrotulado, e, método para formação de imagem de superexpressão de egfr em tumores BRPI0608217A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65513905P 2005-02-22 2005-02-22
PCT/IB2006/000345 WO2006090232A2 (en) 2005-02-22 2006-02-21 Radiolabeled gallium complexes, methods for synthesis and use for pet imaging of egfr epxression in malignant tumors

Publications (1)

Publication Number Publication Date
BRPI0608217A2 true BRPI0608217A2 (pt) 2016-10-11

Family

ID=36927800

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0608217A BRPI0608217A2 (pt) 2005-02-22 2006-02-21 método para síntese de rotulação de complexo de gálio radiorrotulado, complexo de gálio radiorrotulado, e, método para formação de imagem de superexpressão de egfr em tumores

Country Status (12)

Country Link
US (2) US20060188441A1 (pt)
EP (1) EP1850881A2 (pt)
JP (1) JP2008531988A (pt)
KR (1) KR20070106731A (pt)
CN (1) CN101443051A (pt)
AU (1) AU2006217612A1 (pt)
BR (1) BRPI0608217A2 (pt)
CA (1) CA2598863A1 (pt)
MX (1) MX2007010116A (pt)
NO (1) NO20074576L (pt)
RU (1) RU2007131538A (pt)
WO (1) WO2006090232A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
FR2899585B1 (fr) * 2006-04-05 2012-06-15 Guerbet Sa Composes comprenant une partie de reconnaissance d'une cible biologique, couplee a une partie de signal capable de complexer le gallium
US8926945B2 (en) 2005-10-07 2015-01-06 Guerbet Compounds comprising a biological target recognizing part, coupled to a signal part capable of complexing gallium
FR2980193B1 (fr) * 2011-09-15 2014-02-14 Guerbet Sa Procede de purification de produits de contraste
JP6185262B2 (ja) * 2013-03-07 2017-08-23 日本メジフィジックス株式会社 核医学骨画像解析技術
GB201405591D0 (en) * 2014-03-28 2014-05-14 Ge Healthcare Ltd Heatseal
JP6696990B2 (ja) * 2015-01-30 2020-05-20 アドヴァンスド アッチェレラター アプリケーションズ インターナショナル ソシエテ アノニム ６８Ｇｅ／６８Ｇａジェネレーターから生じる溶離液からＧａ−６８を精製する方法および該方法において使用するためのクロマトグラフィーカラム
WO2021234741A1 (en) 2020-05-18 2021-11-25 C.M.S. S.P.A. Microwave device for the rapid labelling of in kit-formulated radiopharmaceuticals
WO2023210510A1 (ja) * 2022-04-27 2023-11-02 日本メジフィジックス株式会社 放射性金属錯体の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4288424A (en) * 1979-01-15 1981-09-08 Massachusetts Institute Of Technology Generator for ionic gallium-68 based on column chromatography
US4330507A (en) * 1980-06-11 1982-05-18 New England Nuclear Corporation Method and system for generating and collecting gallium-68 using alkaline eluant
US5686410A (en) * 1989-07-20 1997-11-11 Novartis Ag Polypeptide derivatives
ATE120374T1 (de) * 1989-07-20 1995-04-15 Sandoz Ag Markierte polypeptidderivate.
EP0614377A1 (en) * 1991-11-14 1994-09-14 Battelle Memorial Institute Method for diagnosing and treating cancer
DE4231622C2 (de) * 1992-09-22 1996-09-05 Bakelite Ag Verfahren zur Herstellung von Metallneutralkomplexen mit hoher Koordinationszahl und deren Verwendung
US6071490A (en) * 1998-05-07 2000-06-06 Immunomedics, Inc. Position emission tomography using gallium-68 chelates
CA2444483A1 (en) * 2001-04-26 2002-11-07 Board Of Regents, The University Of Texas System Diagnostic imaging compositions, their methods of synthesis and use
GB0308408D0 (en) * 2003-04-11 2003-05-21 Amersham Plc Microwave activation
WO2004096254A2 (en) * 2003-05-02 2004-11-11 Xpression Antibody Therapeutics, Inc. Transferrin conjugates for tumor treatment
US20050085417A1 (en) * 2003-10-16 2005-04-21 Thomas Jefferson University Compounds and methods for diagnostic imaging and therapy

Also Published As

Publication number Publication date
AU2006217612A1 (en) 2006-08-31
JP2008531988A (ja) 2008-08-14
US20060188441A1 (en) 2006-08-24
WO2006090232A2 (en) 2006-08-31
CA2598863A1 (en) 2006-08-31
WO2006090232A3 (en) 2007-04-05
CN101443051A (zh) 2009-05-27
EP1850881A2 (en) 2007-11-07
NO20074576L (no) 2007-11-20
MX2007010116A (es) 2007-10-12
KR20070106731A (ko) 2007-11-05
US20110117012A1 (en) 2011-05-19
RU2007131538A (ru) 2009-03-27

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B06H Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
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