BRPI0511714A - composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, método para tratar uma doença em um animal - Google Patents
composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, método para tratar uma doença em um animalInfo
- Publication number
- BRPI0511714A BRPI0511714A BRPI0511714-3A BRPI0511714A BRPI0511714A BR PI0511714 A BRPI0511714 A BR PI0511714A BR PI0511714 A BRPI0511714 A BR PI0511714A BR PI0511714 A BRPI0511714 A BR PI0511714A
- Authority
- BR
- Brazil
- Prior art keywords
- animal
- disease
- treating
- compound
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
COMPOSTO OU UM SAL FARMACEUTICAMENTE ACEITáVEL DO MESMO, COMPOSIçãO FARMACêUTICA, E, MéTODO PARA TRATAR UMA DOENçA EM UM ANIMAL A presente invenção diz respeito a novos inibidores dos Fatores VIIa, IXa, Xa, XIa, em particular do Fator VIIa, composições farmacêuticas que compreendem estes inibidores e métodos para usar estes inibidores para tratar ou prevenir distúrbios tromboembólicos, câncer ou artrite reumatóide. Processos para preparar estes inibidores também são divulgados.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57633004P | 2004-06-02 | 2004-06-02 | |
PCT/US2005/019420 WO2005121102A2 (en) | 2004-06-02 | 2005-06-02 | Factor viia inhibitor |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0511714A true BRPI0511714A (pt) | 2008-01-08 |
Family
ID=35311418
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0511714-3A BRPI0511714A (pt) | 2004-06-02 | 2005-06-02 | composto ou um sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, método para tratar uma doença em um animal |
Country Status (11)
Country | Link |
---|---|
US (1) | US20080242644A1 (pt) |
EP (1) | EP1751114A2 (pt) |
JP (1) | JP2008501702A (pt) |
KR (1) | KR20070038496A (pt) |
CN (1) | CN1976903A (pt) |
AU (1) | AU2005252214A1 (pt) |
BR (1) | BRPI0511714A (pt) |
CA (1) | CA2569170A1 (pt) |
IL (1) | IL179669A0 (pt) |
MX (1) | MXPA06014066A (pt) |
WO (1) | WO2005121102A2 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7479502B2 (en) | 2002-12-03 | 2009-01-20 | Pharmacyclics, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors |
US8729117B2 (en) | 2004-06-02 | 2014-05-20 | Pharmacyclics, Inc. | Factor VIIa inhibitor |
CN102417484A (zh) | 2004-06-02 | 2012-04-18 | 法莫西克立克斯公司 | 因子VIIa抑制剂 |
EA201370191A1 (ru) * | 2007-10-16 | 2014-05-30 | Фармасайкликс, Инк. | КОМПОЗИЦИИ, СОДЕРЖАЩИЕ МОДУЛЯТОРЫ ФАКТОРА КОАГУЛЯЦИИ VIIa, И ИХ ПРИМЕНЕНИЕ |
JP6215239B2 (ja) | 2012-02-21 | 2017-10-18 | ラボラトリオス・デル・ドクトル・エステベ・ソシエダッド・アノニマ | ダビガトランエテキシラートの経口医薬組成物 |
US9399616B2 (en) | 2012-10-22 | 2016-07-26 | Boehringer Ingelheim International Gmbh | Process for the manufacture of 4-aminobenzoamidine dihydrochloride |
KR102635225B1 (ko) | 2018-09-04 | 2024-02-07 | 추가이 세이야쿠 가부시키가이샤 | 4환성 화합물의 제조방법 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9916363A (pt) * | 1998-12-18 | 2001-12-11 | Axys Pharm Inc | Composto, composição farmacêutica e método paratratar ou prevenir um distúrbio tromboembólico |
US20030114457A1 (en) * | 2001-07-09 | 2003-06-19 | Axys Pharmaceuticals, Inc. | 2- [5- (5-carbamimidoyl-1H-heteroaryl)-6-hydroxybiphenyl-3-yl]-succinic acid derivatives as factor viia inhibitors |
US20050203094A1 (en) * | 2002-02-13 | 2005-09-15 | Aleksandr Kolesnikov | 2-[5-(5-carbamimidoyl-1h-heteroaryl)]-6-hydroxybiphenyl-3-yl derivatives as factor viia inhibitors |
US7479502B2 (en) * | 2002-12-03 | 2009-01-20 | Pharmacyclics, Inc. | 2-(2-hydroxybiphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine derivatives as factor VIIA inhibitors |
AU2003300106A1 (en) * | 2003-01-08 | 2004-08-10 | Axys Pharmaceuticals, Inc. | 2-'5-(5-carbamimidoyl-1h-heteroaryl)-6-hydroxybiphenyl-3-yl!- carboxylic acid derivatives as factor viia inhibitors |
-
2005
- 2005-06-02 CN CNA2005800179398A patent/CN1976903A/zh active Pending
- 2005-06-02 JP JP2007515577A patent/JP2008501702A/ja active Pending
- 2005-06-02 MX MXPA06014066A patent/MXPA06014066A/es not_active Application Discontinuation
- 2005-06-02 KR KR1020077000062A patent/KR20070038496A/ko not_active Application Discontinuation
- 2005-06-02 BR BRPI0511714-3A patent/BRPI0511714A/pt not_active Application Discontinuation
- 2005-06-02 AU AU2005252214A patent/AU2005252214A1/en not_active Abandoned
- 2005-06-02 WO PCT/US2005/019420 patent/WO2005121102A2/en active Application Filing
- 2005-06-02 EP EP05790220A patent/EP1751114A2/en not_active Withdrawn
- 2005-06-02 CA CA002569170A patent/CA2569170A1/en not_active Abandoned
- 2005-06-02 US US11/597,334 patent/US20080242644A1/en not_active Abandoned
-
2006
- 2006-11-28 IL IL179669A patent/IL179669A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2005121102A3 (en) | 2006-01-26 |
JP2008501702A (ja) | 2008-01-24 |
AU2005252214A1 (en) | 2005-12-22 |
CA2569170A1 (en) | 2005-12-22 |
US20080242644A1 (en) | 2008-10-02 |
EP1751114A2 (en) | 2007-02-14 |
MXPA06014066A (es) | 2007-02-15 |
WO2005121102A2 (en) | 2005-12-22 |
KR20070038496A (ko) | 2007-04-10 |
IL179669A0 (en) | 2007-05-15 |
CN1976903A (zh) | 2007-06-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |