BRPI0511287A - uso de células-tronco do sangue do cordão umbilical para tratar evento isquêmico - Google Patents

uso de células-tronco do sangue do cordão umbilical para tratar evento isquêmico

Info

Publication number
BRPI0511287A
BRPI0511287A BRPI0511287-7A BRPI0511287A BRPI0511287A BR PI0511287 A BRPI0511287 A BR PI0511287A BR PI0511287 A BRPI0511287 A BR PI0511287A BR PI0511287 A BRPI0511287 A BR PI0511287A
Authority
BR
Brazil
Prior art keywords
stem cells
blood stem
umbilical cord
cord blood
ischemic event
Prior art date
Application number
BRPI0511287-7A
Other languages
English (en)
Inventor
Walter Low
Jing Xiao
Zhenhong Nan
Original Assignee
Univ Minnesota
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Minnesota filed Critical Univ Minnesota
Publication of BRPI0511287A publication Critical patent/BRPI0511287A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/48—Reproductive organs
    • A61K35/51—Umbilical cord; Umbilical cord blood; Umbilical stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0647—Haematopoietic stem cells; Uncommitted or multipotent progenitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)

Abstract

USO DE CéLULAS-TRONCO DO SANGUE DO CORDãO UMBILICAL PARA TRATAR EVENTO ISQUêMICO. A presente invenção refere-se geralmente aos métodos por isolação ou cultivo de células-tronco do sangue do cordão umbilical, células isoladas pelos métodos, e uso terapêuticos para essas células.
BRPI0511287-7A 2004-05-17 2005-05-17 uso de células-tronco do sangue do cordão umbilical para tratar evento isquêmico BRPI0511287A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57216204P 2004-05-17 2004-05-17
PCT/US2005/017373 WO2005112959A2 (en) 2004-05-17 2005-05-17 Use of umbilical cord blood stem cells to treat ischemic event

Publications (1)

Publication Number Publication Date
BRPI0511287A true BRPI0511287A (pt) 2007-12-04

Family

ID=35276173

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0511287-7A BRPI0511287A (pt) 2004-05-17 2005-05-17 uso de células-tronco do sangue do cordão umbilical para tratar evento isquêmico

Country Status (4)

Country Link
US (1) US8309070B2 (pt)
EP (1) EP1753439A2 (pt)
BR (1) BRPI0511287A (pt)
WO (1) WO2005112959A2 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060222634A1 (en) * 2005-03-31 2006-10-05 Clarke Diana L Amnion-derived cell compositions, methods of making and uses thereof
EP2155860B1 (en) 2007-05-03 2014-08-27 The Brigham and Women's Hospital, Inc. Multipotent stem cells and uses thereof
US11318170B2 (en) * 2008-03-28 2022-05-03 Stemcyte, Inc. Treatment of brain damage using umbilical cord blood cells
JP6169316B2 (ja) 2008-08-20 2017-07-26 アンスロジェネシス コーポレーション 改良型細胞組成物およびその作製方法
US8796315B2 (en) 2009-06-25 2014-08-05 Darlene E. McCord Methods for improved wound closure employing olivamine and human umbilical vein endothelial cells
CA2768576C (en) * 2009-07-21 2022-12-06 Abt Holding Company Use of stem cells to reduce leukocyte extravasation
CA2892375A1 (en) 2012-11-30 2014-06-05 Darlene E. MCCORD Hydroxytyrosol and oleuropein compositions for induction of dna damage, cell death and lsd1 inhibition
US10308959B2 (en) 2013-01-18 2019-06-04 Henry Ford Health System Methods, systems, and compositions relating to MiRNA-146a
US20160082049A1 (en) * 2014-09-22 2016-03-24 Henry Ford Health System Methods, systems, and compositions relating to treatment of neurological conditions, diseases, and injuries and complications from diabetes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2169292C (en) 1993-08-12 2010-11-23 E. Edward Baetge Improved compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules
US6015686A (en) 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
US6245757B1 (en) 1997-10-03 2001-06-12 Research Corporation Technologies, Inc. Use of progestins to treat ischemic event
EP2348104A1 (en) 1999-08-05 2011-07-27 Mcl Llc Multipotent adult stem cells and methods for isolation
US7160724B2 (en) * 2000-03-09 2007-01-09 University Of South Florida Human cord blood as a source of neural tissue for repair of the brain and spinal cord
CA2430989A1 (en) 2000-12-06 2002-06-13 Robert J. Hariri Method of collecting placental stem cells
EP2316919B1 (en) 2001-02-14 2015-10-07 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
EP1367899A4 (en) 2001-02-14 2004-07-28 Leo T Furcht TOTIPOTENT ADULT STEM CELLS, SOURCES OF SUCH CELLS, METHODS FOR OBTAINING AND MAINTAINING SAME, METHODS FOR DIFFERENTIATING THESE CELLS, METHODS OF USING SAME, AND CELLS DERIVED FROM THE ABOVE-MENTIONED CELLS
EP1482787A4 (en) 2002-02-13 2006-02-15 Anthrogenesis Corp EMBRYONIC TYPE DERIVED STEM CELLS DERIVED FROM MAMMALIAN POST-PARTUM PLACENTA, USES THEREOF, AND METHODS OF TREATMENT BASED ON CELLS OF THIS TYPE
US20040197310A1 (en) 2003-02-12 2004-10-07 Sanberg Paul R. Compositions and methods for using umbilical cord progenitor cells in the treatment of myocardial infarction
EP1694826A4 (en) 2003-12-15 2007-05-09 Univ South Florida COMPOSITIONS AND METHODS FOR ENHANCING NEUROPROTECTION BY DELIVERY OF STEM CELLS AND PERMEABILIZERS OF BLOOD CEREBRAL BARRIER
US8765119B2 (en) * 2004-05-06 2014-07-01 University Of South Florida Treating amyotrophic lateral sclerosis (ALS)with isolated aldehyde dehydrogenase-positive umbilical cord blood cells

Also Published As

Publication number Publication date
US20070172465A1 (en) 2007-07-26
EP1753439A2 (en) 2007-02-21
WO2005112959A2 (en) 2005-12-01
WO2005112959A3 (en) 2006-01-26
US8309070B2 (en) 2012-11-13

Similar Documents

Publication Publication Date Title
BRPI0511287A (pt) uso de células-tronco do sangue do cordão umbilical para tratar evento isquêmico
HN2012001223A (es) Antagonistas de pcsk 9
MX2010006096A (es) Anticuerpo anti-nr10 y su uso.
EP1784639A4 (en) PROCESS FOR PREPARING FREEZERTED BLOOD PLATES, FLUIDIZED BLOOD PLATES, COMPOSITIONS AND USE METHOD
MY148468A (en) Compounds and methods for kinase modulation, and indications therefor
MX2009006688A (es) Compuestos y metodos para modulacion de cinasas, e indicaciones para ello.
HK1121530A1 (en) Assays for detection of antibodies to lysosomal enzymes
GT201200318A (es) Anticuerpos hacia gdf8 humano
MX348362B (es) Composiciones y metodos para tratar y diagnosticar asma.
BR112013003248A2 (pt) "macrociclo peptidomimético e seus usos"
EA200802213A1 (ru) Способы лечения заболеваний крови
BR112012018132A2 (pt) "marcadores de células - tronco tumorais e uso dos mesmos".
UA95244C2 (ru) Соединения и способ модулирования активности киназ, и показания для их применения
AR078346A1 (es) Anticuerpos humanos de alta afinidad contra el receptor activado por proteasa de tipo 2 humano
WO2007047408A3 (en) Promac signature application
CR20110526A (es) Anticuerpos anti - tnf - alfa y sus usos
MX2009009207A (es) Metodos y composiciones para normalizar las secreciones de glandulas meibomianas.
WO2008021183A3 (en) For the identification, assessment, and treatment of patients with cancer therapy
WO2005117938A3 (en) Methods of treating ocular conditions
DK1725655T3 (da) Cancerøse prostatastamceller
AR062268A1 (es) Agentes ligantes direccionados dirigidos a pdgfr-alfa y sus usos
BRPI0814330B8 (pt) métodos e kits cirúrgicos
PA8618901A1 (es) Biaril sulfonamidas y metodo para el uso de las mismas
CO2018007133A2 (es) Uso de la carrimicina en la infección por micobacterium tuberculosis resistente
WO2008013966A3 (en) Use of 8-quinolinol and its analogs to target cancer stem cells

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]