BRPI0510840A - composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide - Google Patents

composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide

Info

Publication number
BRPI0510840A
BRPI0510840A BRPI0510840-3A BRPI0510840A BRPI0510840A BR PI0510840 A BRPI0510840 A BR PI0510840A BR PI0510840 A BRPI0510840 A BR PI0510840A BR PI0510840 A BRPI0510840 A BR PI0510840A
Authority
BR
Brazil
Prior art keywords
corticosteroid
vitamin
composition
pharmaceutical composition
pressurized
Prior art date
Application number
BRPI0510840-3A
Other languages
English (en)
Inventor
Leila Zarif
Claire Mallard
Original Assignee
Galderma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Sa filed Critical Galderma Sa
Publication of BRPI0510840A publication Critical patent/BRPI0510840A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

COMPOSIçãO FARMACêUTICA, COMPOSIçãO PRESSURIZADA, BOMBA AEROSSOL E USO DE UMA MISTURA DE ANáLOGO DE VITAMINA D E DE UM CORTICOSTERóIDE A presente invenção tem por objeto uma composição farmacêutica espumante de uso tópico, estável, destinada ao tratamento da psoríase, que compreende uma fase hidrófila, pelo menos uma fase hidrófoba, um agente tensoativo, e a título de princípio ativo uma associação de análogo de vitamina D e de corticosteróide e pelo menos um gás propulsor.
BRPI0510840-3A 2004-06-17 2005-06-15 composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide BRPI0510840A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0406613A FR2871696B1 (fr) 2004-06-17 2004-06-17 Composition topique pour le traitement du psoriasis
PCT/FR2005/001496 WO2006005844A1 (fr) 2004-06-17 2005-06-15 Composition moussante pressurisee pour le traitement topique du psoriasis

Publications (1)

Publication Number Publication Date
BRPI0510840A true BRPI0510840A (pt) 2007-11-27

Family

ID=34949090

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0510840-3A BRPI0510840A (pt) 2004-06-17 2005-06-15 composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide

Country Status (12)

Country Link
US (1) US20050281755A1 (pt)
EP (1) EP1778185A1 (pt)
JP (1) JP2008502663A (pt)
KR (1) KR20070024598A (pt)
CN (1) CN1968681A (pt)
AU (1) AU2005261571A1 (pt)
BR (1) BRPI0510840A (pt)
CA (1) CA2567687A1 (pt)
FR (1) FR2871696B1 (pt)
MX (1) MXPA06014409A (pt)
RU (1) RU2007101540A (pt)
WO (1) WO2006005844A1 (pt)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8263580B2 (en) * 1998-09-11 2012-09-11 Stiefel Research Australia Pty Ltd Vitamin formulation
AUPP583198A0 (en) * 1998-09-11 1998-10-01 Soltec Research Pty Ltd Mousse composition
US8512718B2 (en) 2000-07-03 2013-08-20 Foamix Ltd. Pharmaceutical composition for topical application
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
CA2502986C (en) 2002-10-25 2011-08-23 Foamix Ltd. Cosmetic and pharmaceutical foam
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US20060018937A1 (en) * 2002-10-25 2006-01-26 Foamix Ltd. Steroid kit and foamable composition and uses thereof
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US8119150B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US8486376B2 (en) 2002-10-25 2013-07-16 Foamix Ltd. Moisturizing foam containing lanolin
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
US8119109B2 (en) 2002-10-25 2012-02-21 Foamix Ltd. Foamable compositions, kits and methods for hyperhidrosis
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US7575739B2 (en) 2003-04-28 2009-08-18 Foamix Ltd. Foamable iodine composition
US8486374B2 (en) 2003-08-04 2013-07-16 Foamix Ltd. Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US8211449B2 (en) * 2004-06-24 2012-07-03 Dpt Laboratories, Ltd. Pharmaceutically elegant, topical anhydrous aerosol foam
AU2006298442A1 (en) 2005-05-09 2007-04-12 Foamix Ltd. Saccharide foamable compositions
PL2526930T3 (pl) * 2005-06-01 2014-05-30 Glaxosmithkline Ip Dev Ltd Formulacja witaminowa
KR20090039833A (ko) * 2006-08-29 2009-04-22 테바 파마슈티컬 인더스트리즈 리미티드 비타민 ｄ 및 코르티코스테로이드를 포함하는 약학 조성물
GB2443161B (en) * 2006-10-28 2011-03-23 Nupharm Lab Ltd Clobetasol spray
GB2443162B (en) * 2006-10-28 2011-02-09 Nupharm Lab Ltd Betamethasone spray
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US9532936B2 (en) 2007-03-08 2017-01-03 Strength Of Nature, Llc Compositions and methods for removing hair styling aids
EP1970048A1 (en) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Polyaphron topical composition with vitamin D
EP1970049A1 (en) * 2007-03-15 2008-09-17 Drug Delivery Solutions Limited Polyaphron topical composition with vitamin D and corticosteroid
US10265265B2 (en) * 2007-03-15 2019-04-23 Drug Delivery Solutions Limited Topical composition
FR2915097B1 (fr) * 2007-04-18 2012-09-28 Fabre Pierre Dermo Cosmetique Mousse antifongique a base de ciclopiroxolamine et de pyrithione de zinc et ses applications medicales et cosmetiques.
EP2008651A1 (en) 2007-06-26 2008-12-31 Drug Delivery Solutions Limited A bioerodible patch
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
US9439857B2 (en) 2007-11-30 2016-09-13 Foamix Pharmaceuticals Ltd. Foam containing benzoyl peroxide
WO2010041141A2 (en) 2008-10-07 2010-04-15 Foamix Ltd. Oil-based foamable carriers and formulations
WO2009072007A2 (en) 2007-12-07 2009-06-11 Foamix Ltd. Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof
AU2009205314A1 (en) 2008-01-14 2009-07-23 Foamix Ltd. Poloxamer foamable pharmaceutical compositions with active agents and/or therapeutic cells and uses
NZ592300A (en) * 2008-10-03 2013-01-25 Nexmed Holdings Inc Stabilized composition for treating psoriasis
US20120238535A1 (en) * 2009-02-23 2012-09-20 Smith Jan G Topical formulation of low level clobetasol propionate for treating disorders of the skin and mucous membranes
PL2400951T3 (pl) * 2009-02-25 2019-02-28 Mayne Pharma Llc Miejscowa kompozycja pianki
WO2010125470A2 (en) 2009-04-28 2010-11-04 Foamix Ltd. Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof
CA2769625C (en) 2009-07-29 2017-04-11 Foamix Ltd. Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses
CA2769677A1 (en) 2009-07-29 2011-02-03 Foamix Ltd. Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses
WO2011039637A2 (en) 2009-10-02 2011-04-07 Foamix Ltd. Surfactant-free water-free foamable compositions, breakable foams and gels and their uses
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
AU2015203836B2 (en) * 2010-06-11 2016-09-01 Leo Pharma A/S A pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid
CN102939078B (zh) * 2010-06-11 2014-12-24 利奥制药有限公司 含有维生素d类似物和皮质类固醇的药用喷雾剂组合物
HUE045467T2 (hu) 2011-03-14 2020-01-28 Drug Delivery Solutions Ltd Szemészeti készítmény
CN110128370A (zh) 2013-01-29 2019-08-16 埃维克辛公司 抗炎症和抗肿瘤的2-氧代噻唑类和2-氧代噻吩类化合物
JP6396230B2 (ja) * 2014-01-27 2018-09-26 株式会社ポーラファルマ 使用時泡状を呈する外用医薬組成物
JP6396229B2 (ja) * 2014-01-27 2018-09-26 株式会社ポーラファルマ 使用時泡状を呈する外用医薬組成物
GB201413695D0 (en) 2014-08-01 2014-09-17 Avexxin As Compound
FR3041538B1 (fr) * 2015-09-29 2018-11-30 Galderma Research & Development Mousse chimique non rincee contenant du propionate de clobetasol, et son utilisation dans le traitement du psoriasis.
GB201604318D0 (en) 2016-03-14 2016-04-27 Avexxin As Combination therapy
GB201604316D0 (en) 2016-03-14 2016-04-27 Avexxin As Combination therapy
MX2020012139A (es) 2016-09-08 2021-01-29 Vyne Pharmaceuticals Inc Composiciones y metodos para tratar rosacea y acne.
US11351127B2 (en) 2016-09-21 2022-06-07 Avexxin As Pharmaceutical composition
EP3542788A1 (en) 2018-03-19 2019-09-25 MC2 Therapeutics Limited Topical composition comprising calcipotriol and betamethasone dipropionate

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3949098A (en) * 1974-06-05 1976-04-06 Nabisco, Inc. Nutritious orange drink concentrate, process and drink resultant therefrom
US4610978A (en) * 1983-03-22 1986-09-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same
US5223244A (en) * 1988-06-20 1993-06-29 Shiseido Company, Ltd. Aerosol composition
WO1990006060A1 (en) * 1988-12-07 1990-06-14 San-Ei Chemical Industries, Ltd. Method for preparing milk/mineral concentrate and mineralized drink
US5158761A (en) * 1989-04-05 1992-10-27 Toko Yakuhin Kogyo Kabushiki Kaisha Spray gel base and spray gel preparation using thereof
GB9004544D0 (en) * 1990-03-01 1990-04-25 Leo Pharm Prod Ltd Novel treatment ii
US5087620A (en) * 1990-05-17 1992-02-11 Bristol-Myers Squibb Co. Controlled dermal penetration enhancement using imidazoles
US5763426A (en) * 1993-01-15 1998-06-09 Leo Pharmaceutical Products Ltd. Crystalline form of a vitamin D analogue
FR2701396B1 (fr) * 1993-02-12 1995-04-21 Oreal Procédé de stabilisation de vésicules de lipide(s) amphiphile(s) et composition pour application topique contenant lesdites vésicules stabilisées.
FR2740038B1 (fr) * 1995-10-20 1998-01-02 Lafon Labor Composition pour l'administration transdermique
US6126949A (en) * 1998-04-06 2000-10-03 Bernel Chemical Company, Inc. Di-behenyl fumarate and its use in dermatological products
US6106874A (en) * 1998-11-18 2000-08-22 Abbott Laboratories Calcium fortified juice-based nutritional supplement and process of making
EP1178808B2 (en) * 1999-04-23 2019-06-12 Leo Pharma A/S Non-aqueous pharmaceutical composition for dermal use to treat psoriasis comprising a vitamin d, a corticosteroid and a solvent component
US7074747B1 (en) * 1999-07-01 2006-07-11 Johnson & Johnson Consumer Companies, Inc. Cleansing compositions
BRPI0114927B8 (pt) * 2000-10-27 2021-05-25 Leo Pharma As composição de gel farmacêutica não aquosa para aplicação na pele, e, uso de uma composição
US20030059446A1 (en) * 2001-09-18 2003-03-27 Kulkarni Arun B. Physically stable sprayable gel composition
DE60316724T2 (de) * 2002-12-17 2008-07-17 Galderma S.A. Pharmazeutische zusammensetzung enthaltend calcitriol und clobetasolpropionat
FR2848454B1 (fr) * 2002-12-17 2007-03-30 Galderma Res & Dev Composition pharmaceutique comprenant une association de calcitriol et d'un corticosteroide

Also Published As

Publication number Publication date
MXPA06014409A (es) 2007-02-19
CN1968681A (zh) 2007-05-23
RU2007101540A (ru) 2008-07-27
FR2871696B1 (fr) 2006-11-10
FR2871696A1 (fr) 2005-12-23
JP2008502663A (ja) 2008-01-31
WO2006005844A1 (fr) 2006-01-19
AU2005261571A1 (en) 2006-01-19
EP1778185A1 (fr) 2007-05-02
KR20070024598A (ko) 2007-03-02
US20050281755A1 (en) 2005-12-22
CA2567687A1 (fr) 2006-01-19

Similar Documents

Publication Publication Date Title
BRPI0510840A (pt) composição farmacêutica, composição pressurizada, bomba aerossol e uso de uma mistura de análogo de vitamina d e de um corticosteróide
ES2364692T3 (es) Composición espumable esencialmente libre de ingredientes farmacéuticamente activos para el tratamiento de la piel humana.
EP2100601A3 (en) Topical pharmaceutical foam composition
US8486374B2 (en) Hydrophilic, non-aqueous pharmaceutical carriers and compositions and uses
AR046878A1 (es) Agente endoparasiticida para administracion topica
WO2008038147A3 (en) Foamable vehicle comprising dicarboxylic acid or dicarboxylic acid ester and pharmaceutical compositions thereof
BR112012030653A2 (pt) composição tópica em aerosol, estável ao armazenamento e substancialmente anidra, e, recipiente pressurizado
WO2006003481A3 (en) Oleaginous pharmaceutical and cosmetic foam
WO2009090495A3 (en) Oil and liquid silicone foamable carriers and formulations
ECSP088653A (es) Formulacion farmacéutica para aerosoles con dos o más principios activos y al menos una sustancia tensoactiva
BRPI0509708B8 (pt) espuma farmacêutica, composição de espuma de pimecrolimus contendo glicol de hexileno, opcionalmente álcool de oleil, dimetilisosorbídeo e/ou triglicerídeos de cadeia média e uso
GT200900154A (es) Derivados de 2,3-dihidroimidozo [1,2-c] quinizolina sustituidos de utilidad en el tratamiento de trastornos hiperproliferativos y enfermedades asociadas con la angiogenesis
WO2004037197A3 (en) Antifungal formulations
HUP0302007A2 (hu) Gyógyászati célú stabil aeroszol összetétel, inhalátor az aeroszol pontos adagolásához és eljárás ennek feltöltésére
CL2011002053A1 (es) Composicion farmaceutica de espuma en aerosol en emulsion de aceite en agua que comprende un agente farmaceuticamente activo, agua, aceite, disolvente organico, componente tensoactivo, y propulsor; procedimiento de preparacion; uso para tratar enfermedades, o afecciones de la piel.
WO2006129161A3 (en) Vitamin formulation
BR122012030846B8 (pt) composição farmacêutica não aquosa para uso dermatológico compreendendo calcipotriol e pelo menos um corticoesteróide, e, uso da mesma
MX354480B (es) Composiciones espumables de peróxido de benzoilo para administración tópica.
BR112014004967A2 (pt) pré-concentrado lipídico de liberação sustentada e composição farmacêutica
CO4940408A1 (es) Composicion de aerosol farmaceutico
AR044050A1 (es) Utilizacion de ivermectina para el tratamiento de desordenes dermatologicos
WO2008020056A3 (de) Aerosolformulierung enthaltend betaagonisten und steroide
AR054230A1 (es) Formulaciones farmaceuticas en aerosol para inhaladores de cartucho presurizados que comprenden un agente secuestrante
PL1771180T5 (pl) Kompozycja w postaci sprayu zawierająca kombinację propionianu klobetazolu i kalcytriolu, fazę alkoholową i fazę olejową
ECSP099311A (es) Farmaco combinado

Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]