BRPI0506117A - método de diagnóstico baseado em padrões proteÈmicos e/ou genÈmicos por vetores de suporte aplicado a espectometria de massa - Google Patents
método de diagnóstico baseado em padrões proteÈmicos e/ou genÈmicos por vetores de suporte aplicado a espectometria de massaInfo
- Publication number
- BRPI0506117A BRPI0506117A BRPI0506117-2A BRPI0506117A BRPI0506117A BR PI0506117 A BRPI0506117 A BR PI0506117A BR PI0506117 A BRPI0506117 A BR PI0506117A BR PI0506117 A BRPI0506117 A BR PI0506117A
- Authority
- BR
- Brazil
- Prior art keywords
- method based
- mass spectrometry
- diagnostic method
- support vectors
- proteinaceous
- Prior art date
Links
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8675—Evaluation, i.e. decoding of the signal into analytical information
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06F—ELECTRIC DIGITAL DATA PROCESSING
- G06F18/00—Pattern recognition
- G06F18/20—Analysing
- G06F18/21—Design or setup of recognition systems or techniques; Extraction of features in feature space; Blind source separation
- G06F18/211—Selection of the most significant subset of features
- G06F18/2111—Selection of the most significant subset of features by using evolutionary computational techniques, e.g. genetic algorithms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/461—Flow patterns using more than one column with serial coupling of separation columns
- G01N30/463—Flow patterns using more than one column with serial coupling of separation columns for multidimensional chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
Landscapes
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Theoretical Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Data Mining & Analysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Evolutionary Computation (AREA)
- Library & Information Science (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Artificial Intelligence (AREA)
- General Engineering & Computer Science (AREA)
- Physiology (AREA)
- Computing Systems (AREA)
- Bioinformatics & Computational Biology (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Método de diagnóstico baseado em padrões proteómicos e/ou genómicos por vetores de suporte aplicado a espectometria de massa A presente invenção refere-se a um método de diagnóstico médico baseado em padrões proteómicos e/ou genómicos, por meio de dados obtidos em espectros gerados pela espectometria de massa no qual é possível classificar os pacientes quanto ao estágio de infectabilidade. Adicionalmente, a presente invenção também se refere a dois novos biomarcadores para o diagnóstico médico da Doença de Hodgkin. Baseado nas análises de SVM localiza-se as janelas de interesse e posteriormente recorre-se ao espectro de massa para que ocorra a localização dos biomarcadores, de modo que a identificação dos ditos biomarcadores ocorra por meio de um gel 2D ou por meio da espectrometria de massa.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0506117-2A BRPI0506117A (pt) | 2005-10-14 | 2005-10-14 | método de diagnóstico baseado em padrões proteÈmicos e/ou genÈmicos por vetores de suporte aplicado a espectometria de massa |
PCT/BR2006/000214 WO2007041820A2 (en) | 2005-10-14 | 2006-10-16 | A method for identifying protein patterns in mass spectrometry |
US12/083,560 US20100017356A1 (en) | 2005-10-14 | 2006-10-16 | Method for Identifying Protein Patterns in Mass Spectrometry |
EP06804581.4A EP2614367A2 (en) | 2005-10-14 | 2006-10-16 | A method for identifying protein patterns in mass spectrometry |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BRPI0506117-2A BRPI0506117A (pt) | 2005-10-14 | 2005-10-14 | método de diagnóstico baseado em padrões proteÈmicos e/ou genÈmicos por vetores de suporte aplicado a espectometria de massa |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0506117A true BRPI0506117A (pt) | 2007-07-03 |
Family
ID=37943153
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0506117-2A BRPI0506117A (pt) | 2005-10-14 | 2005-10-14 | método de diagnóstico baseado em padrões proteÈmicos e/ou genÈmicos por vetores de suporte aplicado a espectometria de massa |
Country Status (4)
Country | Link |
---|---|
US (1) | US20100017356A1 (pt) |
EP (1) | EP2614367A2 (pt) |
BR (1) | BRPI0506117A (pt) |
WO (1) | WO2007041820A2 (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2550369B8 (en) * | 2010-03-24 | 2016-10-19 | Parker Proteomics, LLC | Methods for conducting genetic analysis using protein polymorphisms |
EP2600284A1 (fr) * | 2011-12-02 | 2013-06-05 | bioMérieux, Inc. | Procédé d'identification de microorganismes par spectrométrie de masse et normalisation de scores |
CN103235030B (zh) * | 2013-03-25 | 2015-06-03 | 江苏易谱恒科技有限公司 | 基于支持向量机和飞行时间质谱的白酒品牌鉴别方法 |
CN104063710B (zh) * | 2014-06-13 | 2017-08-11 | 武汉理工大学 | 基于支持向量机模型的实测光谱曲线中异常光谱剔除方法 |
WO2017158673A1 (ja) * | 2016-03-14 | 2017-09-21 | 株式会社島津製作所 | 質量分析データ解析装置及び質量分析データ解析用プログラム |
CN106528668B (zh) * | 2016-10-23 | 2018-12-25 | 哈尔滨工业大学深圳研究生院 | 一种基于可视化网络的二阶代谢质谱化合物检测方法 |
AU2018324195A1 (en) | 2017-09-01 | 2020-04-02 | Venn Biosciences Corporation | Identification and use of glycopeptides as biomarkers for diagnosis and treatment monitoring |
WO2019126585A1 (en) * | 2017-12-21 | 2019-06-27 | Paypal, Inc | Robust features generation architecture for fraud modeling |
CN108846254B (zh) * | 2018-06-27 | 2021-08-24 | 哈尔滨工业大学(深圳) | 一种二阶代谢质谱多化合物检测方法、存储介质及服务器 |
WO2020081956A1 (en) * | 2018-10-18 | 2020-04-23 | Medimmune, Llc | Methods for determining treatment for cancer patients |
US11531851B2 (en) * | 2019-02-05 | 2022-12-20 | The Regents Of The University Of Michigan | Sequential minimal optimization algorithm for learning using partially available privileged information |
CN111077193B (zh) * | 2019-12-31 | 2021-10-22 | 北京航空航天大学 | 一种电容传感器及对其电容信号进行处理的成像定位方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7617163B2 (en) * | 1998-05-01 | 2009-11-10 | Health Discovery Corporation | Kernels and kernel methods for spectral data |
US6714925B1 (en) * | 1999-05-01 | 2004-03-30 | Barnhill Technologies, Llc | System for identifying patterns in biological data using a distributed network |
US20030064527A1 (en) * | 2001-02-07 | 2003-04-03 | The Regents Of The University Of Michigan | Proteomic differential display |
JP4138486B2 (ja) * | 2001-01-24 | 2008-08-27 | バイオウルフ テクノロジーズ エルエルスィー | データに含まれる複数の特徴の分類方法 |
EP1393196A4 (en) * | 2001-05-07 | 2007-02-28 | Health Discovery Corp | CORES AND METHODS FOR SELECTING CORES FOR USE IN TEACHING MACHINES |
EP1446667A2 (en) * | 2001-11-13 | 2004-08-18 | Caprion Pharmaceuticals, Inc. | Mass intensity profiling system and uses thereof |
US20050048547A1 (en) * | 2003-07-17 | 2005-03-03 | Hongyu Zhao | Classification of disease states using mass spectrometry data |
KR100703528B1 (ko) * | 2004-12-09 | 2007-04-03 | 삼성전자주식회사 | 영상 인식 장치 및 방법 |
-
2005
- 2005-10-14 BR BRPI0506117-2A patent/BRPI0506117A/pt not_active Application Discontinuation
-
2006
- 2006-10-16 WO PCT/BR2006/000214 patent/WO2007041820A2/en active Application Filing
- 2006-10-16 EP EP06804581.4A patent/EP2614367A2/en not_active Withdrawn
- 2006-10-16 US US12/083,560 patent/US20100017356A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP2614367A4 (en) | 2013-07-17 |
WO2007041820A3 (en) | 2009-04-23 |
US20100017356A1 (en) | 2010-01-21 |
WO2007041820A2 (en) | 2007-04-19 |
EP2614367A2 (en) | 2013-07-17 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08E | Application fees: payment of additional fee required [chapter 8.5 patent gazette] |
Free format text: COMPLEMENTAR A RETRIBUICAODA 3A ANUIDADE DE ACORDO COM A TABELA VIGENTE, REFERENTE A GUIA DE RECOLHIMENTO 220800252150. |
|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B08H | Application fees: decision cancelled [chapter 8.8 patent gazette] |
Free format text: REFERENTE RPI 2284 DE 14/10/2014 (COD. 8.5) |
|
B07G | Grant request does not fulfill article 229-c lpi (prior consent of anvisa) [chapter 7.7 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |