BRPI0417204A - formulação de substáncias - ativas de múltiplas fases - Google Patents

formulação de substáncias - ativas de múltiplas fases

Info

Publication number
BRPI0417204A
BRPI0417204A BRPI0417204-3A BRPI0417204A BRPI0417204A BR PI0417204 A BRPI0417204 A BR PI0417204A BR PI0417204 A BRPI0417204 A BR PI0417204A BR PI0417204 A BRPI0417204 A BR PI0417204A
Authority
BR
Brazil
Prior art keywords
phase
formulation
active substance
dispersant
innermost
Prior art date
Application number
BRPI0417204-3A
Other languages
English (en)
Inventor
Daniel Rudhardt
Frank Ridder
Stefan Hofmann
Original Assignee
Bayer Technology Services Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Technology Services Gmbh filed Critical Bayer Technology Services Gmbh
Publication of BRPI0417204A publication Critical patent/BRPI0417204A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/26—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests in coated particulate form
    • A01N25/28—Microcapsules or nanocapsules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N49/00—Biocides, pest repellants or attractants, or plant growth regulators, containing compounds containing the group, wherein m+n>=1, both X together may also mean —Y— or a direct carbon-to-carbon bond, and the carbon atoms marked with an asterisk are not part of any ring system other than that which may be formed by the atoms X, the carbon atoms in square brackets being part of any acyclic or cyclic structure, or the group, wherein A means a carbon atom or Y, n>=0, and not more than one of these carbon atoms being a member of the same ring system, e.g. juvenile insect hormones or mimics thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/066—Multiple emulsions, e.g. water-in-oil-in-water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A61K9/5057—Gelatin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Insects & Arthropods (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"FORMULAçãO DE SUBSTáNCIAS - ATIVAS DE MúLTIPLAS FASES". é descrita uma formulação contendo substâncias - ativas com diversas fases contendo substâncias - ativas, que é caracterizado pelo fato de que a formulação apresenta uma primeira fase (I) finamente dividida mais interna, que consiste de substância - ativa ou solução de substância - ativa, das quais de preferência algumas partículas de fases estão circundadas por um invólucro, e que a formulação apresenta uma segunda fase (11) média, que serve como dispersante para a primeira fase (1) mais interna e a substância-ativa igualmente pode ser dissolvida, e que a formulação apresenta uma terceira fase (III) externa, que serve como dispersante para a segunda fase média e na qual a substância-ativa por sua vez pode ser dissolvida e/ou estar presente na forma de partículas sólidas, que novamente podem ser circundadas por um invólucro de barreira. Além disso é descrito, que neste tipo de diversas substâncias - ativas biologicamente eficazes, podem ser preparadas em uma formulação única, nas diversas fases, em diferentes concentrações e, respectivamente, com uma controlada taxa de liberação. é igualmente descrito que através da solidificação da fase intermedíária (11) é obtida uma estabilização mecânica, que permite um tempo mais longo de formulação estável também após introdução em uma superfície. é igualmente descrito que nas formulações, através da escolha de um solvente apropriado para a fase externa, a liberação da substância -ativa é limitada pela fase mais interna, as cápsulas não são esvaziadas e assim são passíveis de armazenamento por mais tempo.
BRPI0417204-3A 2003-12-19 2004-12-15 formulação de substáncias - ativas de múltiplas fases BRPI0417204A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10359792A DE10359792A1 (de) 2003-12-19 2003-12-19 Mehrphasige Wirkstoffformulierung
PCT/EP2004/014261 WO2005063016A1 (de) 2003-12-19 2004-12-15 Mehrphasige wirkstoffformulierung

Publications (1)

Publication Number Publication Date
BRPI0417204A true BRPI0417204A (pt) 2007-02-06

Family

ID=34683576

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417204-3A BRPI0417204A (pt) 2003-12-19 2004-12-15 formulação de substáncias - ativas de múltiplas fases

Country Status (9)

Country Link
US (1) US20070104795A1 (pt)
EP (1) EP1708567A1 (pt)
JP (1) JP2007514686A (pt)
AU (1) AU2004308077A1 (pt)
BR (1) BRPI0417204A (pt)
CA (1) CA2550351A1 (pt)
DE (1) DE10359792A1 (pt)
NO (1) NO20063192L (pt)
WO (1) WO2005063016A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005030017A1 (de) * 2005-06-27 2007-01-04 Beiersdorf Ag Emulsion mit Repellentien
GB0526416D0 (en) 2005-12-23 2006-02-08 Syngenta Ltd Formulation
US9186640B2 (en) * 2007-08-28 2015-11-17 Pepsico, Inc. Delivery and controlled release of encapsulated lipophilic nutrients
EP2550863A1 (de) * 2011-07-27 2013-01-30 Bayer Intellectual Property GmbH Aktivstoffhaltige Partikel auf Polyacrylat-Basis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB568009A (en) * 1942-11-24 1945-03-14 Harry Hurst Improvements in or relating to toxicological preparations
GB929403A (en) * 1958-12-22 1963-06-19 Upjohn Co Encapsulated emulsions and processes for their preparation
WO1983003061A1 (en) * 1982-03-04 1983-09-15 Battelle Development Corp Dual microcapsules
GB9410092D0 (en) * 1994-05-19 1994-07-06 Kelco Int Ltd Emulsion, method and use
KR100620935B1 (ko) * 1998-03-19 2006-09-13 브리스톨-마이어스스퀴브컴파니 용해도가 높은 약물에 대한 2상 서방성 전달 시스템과 방법
DE19947147A1 (de) * 1999-10-01 2001-04-05 Bayer Ag Mikrokapseln
EP1499303A4 (en) * 2002-04-10 2007-07-25 Fred H Miller MULTIPHASE MULTI-COMPONENT CAPSULE SYSTEM

Also Published As

Publication number Publication date
JP2007514686A (ja) 2007-06-07
EP1708567A1 (de) 2006-10-11
DE10359792A1 (de) 2005-07-21
NO20063192L (no) 2006-09-14
CA2550351A1 (en) 2005-07-14
AU2004308077A1 (en) 2005-07-14
US20070104795A1 (en) 2007-05-10
WO2005063016A1 (de) 2005-07-14

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]