BRPI0416317A - composições, kits e métodos para o tratamento de condições associadas a nìveis elevados de colesterol - Google Patents
composições, kits e métodos para o tratamento de condições associadas a nìveis elevados de colesterolInfo
- Publication number
- BRPI0416317A BRPI0416317A BRPI0416317-6A BRPI0416317A BRPI0416317A BR PI0416317 A BRPI0416317 A BR PI0416317A BR PI0416317 A BRPI0416317 A BR PI0416317A BR PI0416317 A BRPI0416317 A BR PI0416317A
- Authority
- BR
- Brazil
- Prior art keywords
- kits
- compositions
- methods
- hmg coa
- high cholesterol
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 8
- 239000000203 mixture Substances 0.000 title abstract 7
- 235000012000 cholesterol Nutrition 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 abstract 5
- 230000015572 biosynthetic process Effects 0.000 abstract 3
- 239000000835 fiber Substances 0.000 abstract 3
- 229940121710 HMGCoA reductase inhibitor Drugs 0.000 abstract 2
- 108010000775 Hydroxymethylglutaryl-CoA synthase Proteins 0.000 abstract 2
- 102100028888 Hydroxymethylglutaryl-CoA synthase, cytoplasmic Human genes 0.000 abstract 2
- 208000035150 Hypercholesterolemia Diseases 0.000 abstract 2
- 239000002471 hydroxymethylglutaryl coenzyme A reductase inhibitor Substances 0.000 abstract 2
- 229940096701 plain lipid modifying drug hmg coa reductase inhibitors Drugs 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/401—Proline; Derivatives thereof, e.g. captopril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/717—Celluloses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"COMPOSIçõES, KITS E MéTODOS PARA O TRATAMENTO DE CONDIçõES ASSOCIADAS A NìVEIS ELEVADOS DE COLESTEROL". A presente invenção refere-se a, métodos para tratamento de uma condição associada a níveis elevados de colesterol, compreendendo a administração, a um mamífero precisando de tal tratamento, de uma quantidade segura e eficaz de um inibidor da biossíntese do colesterol e de uma fibra solúvel. São apresentados na presente invenção, ainda, kits que compreendem uma primeira composição compreendendo um inibidor da biossíntese do colesterol selecionado do grupo consistindo em inibidores da HMG CoA redutase, inibidores da HMG CoA sintase e misturas dos mesmos, e uma segunda composição compreendendo uma fibra solúvel. São descritas, também, composições compreendendo um inibidor da biossíntese do colesterol selecionado do grupo consistindo em inibidores da HMG CoA redutase, inibidores da HMG CoA sintase e misturas dos mesmos, bem como uma fibra solúvel.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51818303P | 2003-11-07 | 2003-11-07 | |
| PCT/US2004/037427 WO2005046796A2 (en) | 2003-11-07 | 2004-11-08 | Combinations of a cholesterol biosynthesis inhibitor and a soluble fiber for the treatment of conditions associated with elevated cholesterol levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0416317A true BRPI0416317A (pt) | 2007-01-09 |
Family
ID=34590231
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0416317-6A BRPI0416317A (pt) | 2003-11-07 | 2004-11-08 | composições, kits e métodos para o tratamento de condições associadas a nìveis elevados de colesterol |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20050250734A1 (pt) |
| EP (1) | EP1680102A2 (pt) |
| JP (1) | JP2007510743A (pt) |
| CN (1) | CN101014335A (pt) |
| AU (2) | AU2004289297A1 (pt) |
| BR (1) | BRPI0416317A (pt) |
| CA (1) | CA2545204A1 (pt) |
| MX (1) | MXPA06005094A (pt) |
| RU (1) | RU2345762C2 (pt) |
| WO (1) | WO2005046796A2 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060165824A1 (en) * | 2005-01-26 | 2006-07-27 | The Procter & Gamble Company | Compositions, kits, and methods for enhancing gastrointestinal health |
| JP4939781B2 (ja) * | 2005-08-10 | 2012-05-30 | 株式会社健康家族 | ニンニク成分を含有する高血圧の予防及び／又は治療用組成物 |
| EP2568992A4 (en) * | 2010-05-11 | 2013-11-06 | Benzion Geshuri | PHARMACEUTICAL COMPOSITION COMPRISING AN ALGUE APPROPRIATE FOR INCREASING THE EFFICACY OF AN ENZYMATIC INHIBITOR |
| RU2591079C2 (ru) * | 2014-12-10 | 2016-07-10 | Александр Владимирович Диковский | Фармацевтическая композиция статинов с пребиотиком для терапии гиперхолестеринемии и гиперлипидимии |
| US11925660B2 (en) | 2018-08-10 | 2024-03-12 | Simeon Investment, Inc. | Treatment for obesity with superabsorbent materials |
| US11918602B2 (en) | 2018-08-10 | 2024-03-05 | Simeon Investment, Inc. | Methods for reducing cholesterol with superabsorbent materials |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993013801A1 (en) * | 1992-01-17 | 1993-07-22 | The Procter & Gamble Company | Treatment for atherosclerosis |
| GB2329334A (en) * | 1997-09-18 | 1999-03-24 | Reckitt & Colmann Prod Ltd | Cholesterol-lowering agents |
| US6287609B1 (en) * | 1999-06-09 | 2001-09-11 | Wisconsin Alumni Research Foundation | Unfermented gel fraction from psyllium seed husks |
| US6933291B2 (en) * | 2000-12-01 | 2005-08-23 | N.V. Nutricia | Cholesterol lowering supplement |
-
2004
- 2004-11-02 US US10/979,329 patent/US20050250734A1/en not_active Abandoned
- 2004-11-08 EP EP04810629A patent/EP1680102A2/en not_active Withdrawn
- 2004-11-08 MX MXPA06005094A patent/MXPA06005094A/es active IP Right Grant
- 2004-11-08 BR BRPI0416317-6A patent/BRPI0416317A/pt not_active IP Right Cessation
- 2004-11-08 CN CNA2004800329051A patent/CN101014335A/zh active Pending
- 2004-11-08 CA CA002545204A patent/CA2545204A1/en not_active Abandoned
- 2004-11-08 RU RU2006114579/14A patent/RU2345762C2/ru not_active IP Right Cessation
- 2004-11-08 JP JP2006539777A patent/JP2007510743A/ja active Pending
- 2004-11-08 WO PCT/US2004/037427 patent/WO2005046796A2/en active Application Filing
- 2004-11-08 AU AU2004289297A patent/AU2004289297A1/en not_active Abandoned
-
2009
- 2009-01-27 AU AU2009200290A patent/AU2009200290A1/en not_active Abandoned
-
2012
- 2012-04-25 US US13/455,595 patent/US20120282359A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005046796A3 (en) | 2006-05-26 |
| US20120282359A1 (en) | 2012-11-08 |
| RU2006114579A (ru) | 2007-12-27 |
| US20050250734A1 (en) | 2005-11-10 |
| AU2009200290A1 (en) | 2009-02-19 |
| MXPA06005094A (es) | 2007-01-25 |
| EP1680102A2 (en) | 2006-07-19 |
| CN101014335A (zh) | 2007-08-08 |
| CA2545204A1 (en) | 2005-05-26 |
| WO2005046796A2 (en) | 2005-05-26 |
| JP2007510743A (ja) | 2007-04-26 |
| RU2345762C2 (ru) | 2009-02-10 |
| AU2004289297A1 (en) | 2005-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2144 DE 07/02/2012. |
|
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 31/366 (2006.01), A61K 31/216 (2006.01), A61K |