BRPI0409370A - compostos de amÈnio quaternário e seus usos como agentes antimuscarìnicos - Google Patents
compostos de amÈnio quaternário e seus usos como agentes antimuscarìnicosInfo
- Publication number
- BRPI0409370A BRPI0409370A BRPI0409370-4A BRPI0409370A BRPI0409370A BR PI0409370 A BRPI0409370 A BR PI0409370A BR PI0409370 A BRPI0409370 A BR PI0409370A BR PI0409370 A BRPI0409370 A BR PI0409370A
- Authority
- BR
- Brazil
- Prior art keywords
- quaternary ammonium
- ammonium compounds
- compounds
- antimuscarinic agents
- agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/66—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with quaternised amino groups bound to the carbon skeleton
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
"COMPOSTOS DE AMÈNIO QUATERNáRIO E SEUS USOS COMO AGENTES ANTIMUSCARìNICOS". A presente invenção refere-se a compostos de amónio quaternário da fórmula e quaisquer estereoisómeros destes, em que R~ 1~, R~ 2~, R~ 3~, R~ 4~, R~ 5~, R~ 6~, R~ 7~ e X¬ -¬ são aqui definidos. Os compostos são úteis como medicamentos para o tratamento de asma, um grupo de distúrbios respiratórios designado por Doença Pulmonar Obstrutiva Crónica (COPD), rinite alérgica, rinorréia devido à constipação e distúrbio urinário.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US46295603P | 2003-04-15 | 2003-04-15 | |
PCT/IB2004/001290 WO2004091607A1 (en) | 2003-04-15 | 2004-04-13 | Quaternary ammonium compounds and their use as antimuscarinic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0409370A true BRPI0409370A (pt) | 2006-04-25 |
Family
ID=33300019
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0409370-4A BRPI0409370A (pt) | 2003-04-15 | 2004-04-13 | compostos de amÈnio quaternário e seus usos como agentes antimuscarìnicos |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040242569A1 (pt) |
EP (1) | EP1622606A1 (pt) |
JP (1) | JP2006523676A (pt) |
BR (1) | BRPI0409370A (pt) |
CA (1) | CA2522102A1 (pt) |
MX (1) | MXPA05011059A (pt) |
WO (1) | WO2004091607A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050130990A1 (en) * | 2001-03-23 | 2005-06-16 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
CA2341952A1 (en) | 2001-03-23 | 2002-09-23 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory pulmonary diseases |
CA2464223C (en) * | 2001-10-26 | 2009-05-26 | Pharmacia & Upjohn Company | Quarternary ammonium compounds and their use as antimuscarinic agents |
US8039459B2 (en) | 2004-07-15 | 2011-10-18 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
US8557804B2 (en) | 2002-03-25 | 2013-10-15 | Universite Laval | Nicotinic receptor agonists for the treatment of inflammatory diseases |
AU2005318426B2 (en) * | 2004-12-24 | 2011-05-19 | Lek Pharmaceuticals D.D. | Process for preparation of 3-(2-hydroxy-5-methylphenyl)-N,N-diisopropyl-3-phenylpropylamine |
CN110372571B (zh) * | 2018-04-12 | 2022-11-15 | 中国科学院大连化学物理研究所 | 一种2-(2,2-二芳基乙基)-环胺衍生物或盐及合成和应用与组合物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL6717123A (pt) * | 1966-12-29 | 1968-07-01 | ||
US3505337A (en) * | 1967-12-22 | 1970-04-07 | Boehringer Sohn Ingelheim | N - hydrocarbyl-substituted noratropinium,haloalkylates and o-acyl derivatives thereof |
US5382600A (en) * | 1988-01-22 | 1995-01-17 | Pharmacia Aktiebolag | 3,3-diphenylpropylamines and pharmaceutical compositions thereof |
IL91377A (en) * | 1988-09-14 | 1996-09-12 | Nippon Shinyaku Co Ltd | Derivatives of botinylamine glycolate |
GB8906166D0 (en) * | 1989-03-17 | 1989-05-04 | Pfizer Ltd | Therapeutic agents |
US5610163A (en) * | 1989-09-16 | 1997-03-11 | Boehringer Ingelheim Gmbh | Esters of thienyl carboxylic acids and amino alcohols and their quaternization products |
PE20020547A1 (es) * | 2000-10-24 | 2002-06-12 | Upjohn Co | Uso de la tolterodina en tratamientos del asma |
US20020169208A1 (en) * | 2001-04-03 | 2002-11-14 | Pascal Druzgala | Novel anticholinergic compounds and methods of use |
CA2464223C (en) * | 2001-10-26 | 2009-05-26 | Pharmacia & Upjohn Company | Quarternary ammonium compounds and their use as antimuscarinic agents |
-
2004
- 2004-04-13 MX MXPA05011059A patent/MXPA05011059A/es not_active Application Discontinuation
- 2004-04-13 US US10/823,965 patent/US20040242569A1/en not_active Abandoned
- 2004-04-13 EP EP04727066A patent/EP1622606A1/en not_active Withdrawn
- 2004-04-13 CA CA002522102A patent/CA2522102A1/en not_active Abandoned
- 2004-04-13 BR BRPI0409370-4A patent/BRPI0409370A/pt not_active Application Discontinuation
- 2004-04-13 JP JP2006506538A patent/JP2006523676A/ja active Pending
- 2004-04-13 WO PCT/IB2004/001290 patent/WO2004091607A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1622606A1 (en) | 2006-02-08 |
WO2004091607A1 (en) | 2004-10-28 |
CA2522102A1 (en) | 2004-10-28 |
MXPA05011059A (es) | 2005-12-12 |
US20040242569A1 (en) | 2004-12-02 |
JP2006523676A (ja) | 2006-10-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |