BRPI0408979A - uso de um antagonista e receptor de tipo 1 da angiotensina ii sozinho ou em combinação com uma substáncia anti-hipertensiva metabolicamente neutra, e, método para o tratamento e/ou prevenção de sìndrome metabólica - Google Patents
uso de um antagonista e receptor de tipo 1 da angiotensina ii sozinho ou em combinação com uma substáncia anti-hipertensiva metabolicamente neutra, e, método para o tratamento e/ou prevenção de sìndrome metabólicaInfo
- Publication number
- BRPI0408979A BRPI0408979A BRPI0408979-0A BRPI0408979A BRPI0408979A BR PI0408979 A BRPI0408979 A BR PI0408979A BR PI0408979 A BRPI0408979 A BR PI0408979A BR PI0408979 A BRPI0408979 A BR PI0408979A
- Authority
- BR
- Brazil
- Prior art keywords
- angiotensin
- type
- prevention
- treatment
- combination
- Prior art date
Links
- 239000002220 antihypertensive agent Substances 0.000 title abstract 4
- 230000007935 neutral effect Effects 0.000 title abstract 4
- 230000002265 prevention Effects 0.000 title abstract 3
- 102000005862 Angiotensin II Human genes 0.000 title abstract 2
- 101800000733 Angiotensin-2 Proteins 0.000 title abstract 2
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 title abstract 2
- 208000001145 Metabolic Syndrome Diseases 0.000 title abstract 2
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 title abstract 2
- 229950006323 angiotensin ii Drugs 0.000 title abstract 2
- 239000005557 antagonist Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000400 angiotensin II type 1 receptor blocker Substances 0.000 abstract 2
- 229940127291 Calcium channel antagonist Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0300988A SE0300988D0 (sv) | 2003-04-03 | 2003-04-03 | New use |
| PCT/SE2004/000505 WO2004087136A1 (en) | 2003-04-03 | 2004-03-31 | Use of atii antagonist for the treatment or prevention of metabolic syndrome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0408979A true BRPI0408979A (pt) | 2006-04-04 |
Family
ID=20290927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0408979-0A BRPI0408979A (pt) | 2003-04-03 | 2004-03-31 | uso de um antagonista e receptor de tipo 1 da angiotensina ii sozinho ou em combinação com uma substáncia anti-hipertensiva metabolicamente neutra, e, método para o tratamento e/ou prevenção de sìndrome metabólica |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20060194856A1 (https=) |
| EP (1) | EP1613309A1 (https=) |
| JP (1) | JP2006522115A (https=) |
| KR (1) | KR20050114671A (https=) |
| CN (1) | CN1771033A (https=) |
| AU (1) | AU2004226517B2 (https=) |
| BR (1) | BRPI0408979A (https=) |
| CA (1) | CA2520960A1 (https=) |
| IL (1) | IL170706A0 (https=) |
| MX (1) | MXPA05010660A (https=) |
| NO (1) | NO20054370L (https=) |
| NZ (1) | NZ542640A (https=) |
| SE (1) | SE0300988D0 (https=) |
| WO (1) | WO2004087136A1 (https=) |
| ZA (1) | ZA200507945B (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008067378A2 (en) * | 2006-11-28 | 2008-06-05 | Auspex Pharmaceuticals, Inc. | Preparation and utility of substituted phenyltetrazoles |
| JP2015509969A (ja) * | 2012-03-16 | 2015-04-02 | グルソックス・バイオテック・アーベー | Ｎｏｘ４阻害活性を示すチオフェン−ベースの化合物および療法におけるその使用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5196444A (en) * | 1990-04-27 | 1993-03-23 | Takeda Chemical Industries, Ltd. | 1-(cyclohexyloxycarbonyloxy)ethyl 2-ethoxy-1-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]benzimidazole-7-carboxylate and compositions and methods of pharmaceutical use thereof |
| US5266583A (en) * | 1992-09-01 | 1993-11-30 | Merck & Co., Inc. | Angitotensin II antagonist |
| GB9406573D0 (en) * | 1994-03-31 | 1994-05-25 | Merck Sharp & Dohme | Medicaments |
| DE4439947A1 (de) * | 1994-11-09 | 1996-05-15 | Boehringer Mannheim Gmbh | 2,2-Dichloralkancarbonsäuren, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
| NZ509260A (en) * | 1998-07-10 | 2003-09-26 | Novartis Ag | Pharmaceutical composition containing valsartan and a calcium channel blocker |
| IL152081A0 (en) * | 2000-04-12 | 2003-05-29 | Novartis Ag | Novel medical use of aldosterone synthase inhibitors alone or in combination with at1-receptor antagonists |
| CA2420055C (en) * | 2000-08-25 | 2010-06-01 | Takeda Chemical Industries, Ltd. | Fibrinogen-lowering agent |
| US8168616B1 (en) * | 2000-11-17 | 2012-05-01 | Novartis Ag | Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension |
| US20030092736A1 (en) * | 2001-05-30 | 2003-05-15 | Cheng Peter T. | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method |
| US7232828B2 (en) * | 2002-08-10 | 2007-06-19 | Bethesda Pharmaceuticals, Inc. | PPAR Ligands that do not cause fluid retention, edema or congestive heart failure |
| EP1579872B8 (en) * | 2002-12-27 | 2012-11-07 | Takeda Pharmaceutical Company Limited | Body weight gain inhibitor |
-
2003
- 2003-04-03 SE SE0300988A patent/SE0300988D0/xx unknown
-
2004
- 2004-03-31 EP EP04724927A patent/EP1613309A1/en not_active Ceased
- 2004-03-31 AU AU2004226517A patent/AU2004226517B2/en not_active Ceased
- 2004-03-31 CN CNA2004800093941A patent/CN1771033A/zh active Pending
- 2004-03-31 KR KR1020057017718A patent/KR20050114671A/ko not_active Ceased
- 2004-03-31 US US10/550,760 patent/US20060194856A1/en not_active Abandoned
- 2004-03-31 MX MXPA05010660A patent/MXPA05010660A/es active IP Right Grant
- 2004-03-31 NZ NZ542640A patent/NZ542640A/en not_active IP Right Cessation
- 2004-03-31 CA CA002520960A patent/CA2520960A1/en not_active Abandoned
- 2004-03-31 JP JP2006507997A patent/JP2006522115A/ja active Pending
- 2004-03-31 WO PCT/SE2004/000505 patent/WO2004087136A1/en not_active Ceased
- 2004-03-31 BR BRPI0408979-0A patent/BRPI0408979A/pt not_active IP Right Cessation
-
2005
- 2005-09-06 IL IL170706A patent/IL170706A0/en unknown
- 2005-09-21 NO NO20054370A patent/NO20054370L/no not_active Application Discontinuation
- 2005-09-30 ZA ZA200507945A patent/ZA200507945B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20060194856A1 (en) | 2006-08-31 |
| MXPA05010660A (es) | 2005-12-12 |
| IL170706A0 (en) | 2009-02-11 |
| NZ542640A (en) | 2008-06-30 |
| AU2004226517A1 (en) | 2004-10-14 |
| NO20054370D0 (no) | 2005-09-21 |
| AU2004226517B2 (en) | 2008-01-24 |
| ZA200507945B (en) | 2007-04-25 |
| WO2004087136A1 (en) | 2004-10-14 |
| CN1771033A (zh) | 2006-05-10 |
| KR20050114671A (ko) | 2005-12-06 |
| CA2520960A1 (en) | 2004-10-14 |
| JP2006522115A (ja) | 2006-09-28 |
| EP1613309A1 (en) | 2006-01-11 |
| NO20054370L (no) | 2005-10-31 |
| SE0300988D0 (sv) | 2003-04-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: PARA: INT. CL. A61K 31/41; A61P 9/12 Ipc: A61K 31/41 (2011.01), A61P 9/12 (2011.01) |
|
| B08L | Patent application lapsed because of non payment of annual fee [chapter 8.12 patent gazette] |
Free format text: REFERENTE AO NAO RECOLHIMENTO DAS 9A E 10A ANUIDADES. |
|
| B08I | Publication cancelled [chapter 8.9 patent gazette] |
Free format text: ANULADA A PUBLICACAO CODIGO 8.12 NA RPI NO 2258 DE 15/04/2014 POR TER SIDO INDEVIDA. |
|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 9A, 10A, 11A, 12A, 13A, 14A, 15A E 16A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2602 DE 17-11-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |