BRPI0406680A - Métodos para selecionar um animal para ter propriedades desejadas genotìpicas ou fenotìpicas em potencial, para modular a trascrição de mrna de um gene igf2 em uma célula ou organismo provido com referido gene e para identificar um composto, composto, composição farmacêutica, e, uso de um composto - Google Patents

Métodos para selecionar um animal para ter propriedades desejadas genotìpicas ou fenotìpicas em potencial, para modular a trascrição de mrna de um gene igf2 em uma célula ou organismo provido com referido gene e para identificar um composto, composto, composição farmacêutica, e, uso de um composto

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Publication number
BRPI0406680A
BRPI0406680A BR0406680-4A BRPI0406680A BRPI0406680A BR PI0406680 A BRPI0406680 A BR PI0406680A BR PI0406680 A BRPI0406680 A BR PI0406680A BR PI0406680 A BRPI0406680 A BR PI0406680A
Authority
BR
Brazil
Prior art keywords
gene
compound
cell
igf2 gene
igf2
Prior art date
Application number
BR0406680-4A
Other languages
English (en)
Inventor
Leif Andersson
Goran Andersson
Michel Georges
Nadine Buys
Original Assignee
Univ Liege
Melica Hb
Gentec Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Liege, Melica Hb, Gentec Bv filed Critical Univ Liege
Publication of BRPI0406680A publication Critical patent/BRPI0406680A/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/124—Animal traits, i.e. production traits, including athletic performance or the like
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"MéTODOS PARA SELECIONAR UM ANIMAL PARA TER PROPRIEDADES DESEJADAS GENOTìPICAS OU FENOTìPICAS EM POTENCIAL, PARA MODULAR A TRANSCRIçãO DE MRNA DE UM GENE IGF2 EM UMA CéLULA OU ORGANISMO PROVIDO COM REFERIDO GENE E PARA IDENTIFICAR UM COMPOSTO, COMPOSTO, COMPOSIçãO FARMACêUTICA, E, USO DE UM COMPOSTO". A invenção refere-se a métodos para selecionar animais, como mamíferos, particularmente animais domésticos como animais de criação ou animais destinados para o abate de modo a terem desejadas propriedades genotípicas ou fenotípicas em potencial, particularmente relacionadas com a massa muscular e/ou deposição de gordura ou, no caso de manúferos, ao número de tetas. A invenção provê um método para selecionar um animal para ter as desejadas propriedades genotípicas ou fenotípicas em potencial compreendendo testar o referido animal, um parental do referido animal ou sua progênie para a presença de modificação de ácido nucleico afetando a atividade de uma ilha CpG conservada evolucionária, localizada no intron 3 de um gene IGF2 e/ou pela presença de uma modificação de ácido nucleico afetando a ligação de um fator nuclear para um gene IGF2.
BR0406680-4A 2003-01-10 2004-01-09 Métodos para selecionar um animal para ter propriedades desejadas genotìpicas ou fenotìpicas em potencial, para modular a trascrição de mrna de um gene igf2 em uma célula ou organismo provido com referido gene e para identificar um composto, composto, composição farmacêutica, e, uso de um composto BRPI0406680A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03075091A EP1437418B1 (en) 2003-01-10 2003-01-10 Selecting animals for desired genotypic or potential phenotypic properties based on a single nucleotide polymorphism (SNP) in intron 3 of the IGF2 gene
PCT/EP2004/000149 WO2004063386A2 (en) 2003-01-10 2004-01-09 Selecting animals for desired genotypic or potential phenotypic properties based on a single nucleotide polymorphism (snp) in intron 3 of the igf2 gene

Publications (1)

Publication Number Publication Date
BRPI0406680A true BRPI0406680A (pt) 2005-12-20

Family

ID=32479929

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0406680-4A BRPI0406680A (pt) 2003-01-10 2004-01-09 Métodos para selecionar um animal para ter propriedades desejadas genotìpicas ou fenotìpicas em potencial, para modular a trascrição de mrna de um gene igf2 em uma célula ou organismo provido com referido gene e para identificar um composto, composto, composição farmacêutica, e, uso de um composto

Country Status (10)

Country Link
US (3) US20060037090A1 (pt)
EP (1) EP1437418B1 (pt)
AT (1) ATE440967T1 (pt)
AU (1) AU2004204182A1 (pt)
BR (1) BRPI0406680A (pt)
CA (1) CA2513039A1 (pt)
DE (1) DE60328959D1 (pt)
DK (1) DK1437418T3 (pt)
NZ (1) NZ541698A (pt)
WO (1) WO2004063386A2 (pt)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE366823T1 (de) 1998-12-16 2007-08-15 Univ Liege Auswahl von tieren nach parental geprägten merkmalen
AU2003303599B8 (en) 2002-12-31 2010-03-25 Branhaven LLC Compositions, methods and systems for inferring bovine traits
DE60328959D1 (de) * 2003-01-10 2009-10-08 Univ Liege Auswahl von Tieren für gewünschte genotypische und potentielle phänotypische Eigenschaften auf der Basis eines einzelnen Nukleotidpolymorphismus (SNP) im Intron 3 des IGF2-Gens
WO2007133075A2 (en) * 2006-05-12 2007-11-22 Institute For Pig Genetics B.V. Igf2 marker assisted selection for porcine reproductive traits
WO2009011847A2 (en) * 2007-07-16 2009-01-22 Pfizer Inc. Methods of improving a genomic marker index of dairy animals and products
EP2027771B1 (en) * 2007-08-24 2012-06-13 Hermitage Pedigree Pigs Ltd. Sequencing the mitochondrial DNA with reference to the fertility as a means for the optimization of sow breeding lines
US20110123983A1 (en) * 2007-09-12 2011-05-26 Pfizer Inc. Methods of Using Genetic Markers and Related Epistatic Interactions
WO2009073397A1 (en) 2007-11-29 2009-06-11 Monsanto Technology Llc Meat products with increased levels of beneficial fatty acids
CN101952718A (zh) * 2007-12-17 2011-01-19 美国辉瑞有限公司 改善产乳动物和产品的遗传图谱的方法
DE102012109704A1 (de) * 2012-10-11 2014-04-17 Epcos Ag Keramisches Bauelement mit Schutzschicht und Verfahren zu dessen Herstellung
KR101595011B1 (ko) * 2013-03-28 2016-02-18 대한민국 돼지의 유두 수 판단용 ｓｎｐ 마커 및 이의 용도
WO2017096218A1 (en) * 2015-12-03 2017-06-08 The Penn State Research Foundation Genomic regions with epigenetic variation that contribute to phenotypic differences in livestock
CN107779517B (zh) * 2017-10-26 2018-12-21 华南农业大学 一种影响杜洛克种猪瘦肉率性状的分子标记及其应用
CN110714082B (zh) * 2019-09-03 2021-10-15 中国农业大学 一种与猪乳头数相关的snp位点及其检测方法和应用
CN114807384B (zh) * 2022-04-14 2022-11-25 华南农业大学 一种与鸡屠体性状相关的snp分子标记及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE366823T1 (de) * 1998-12-16 2007-08-15 Univ Liege Auswahl von tieren nach parental geprägten merkmalen
DE60328959D1 (de) 2003-01-10 2009-10-08 Univ Liege Auswahl von Tieren für gewünschte genotypische und potentielle phänotypische Eigenschaften auf der Basis eines einzelnen Nukleotidpolymorphismus (SNP) im Intron 3 des IGF2-Gens

Also Published As

Publication number Publication date
US20070006333A1 (en) 2007-01-04
WO2004063386A3 (en) 2004-09-30
US20060037090A1 (en) 2006-02-16
EP1437418A1 (en) 2004-07-14
US20100281547A1 (en) 2010-11-04
ATE440967T1 (de) 2009-09-15
DK1437418T3 (da) 2009-12-21
NZ541698A (en) 2007-05-31
US7732137B2 (en) 2010-06-08
EP1437418B1 (en) 2009-08-26
AU2004204182A1 (en) 2004-07-29
WO2004063386A2 (en) 2004-07-29
DE60328959D1 (de) 2009-10-08
CA2513039A1 (en) 2004-07-29

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