BRPI0400893A - Process for obtaining clinically dextran oligosaccharides and fructose from sucrose - Google Patents

Process for obtaining clinically dextran oligosaccharides and fructose from sucrose

Info

Publication number
BRPI0400893A
BRPI0400893A BRPI0400893A BRPI0400893A BR PI0400893 A BRPI0400893 A BR PI0400893A BR PI0400893 A BRPI0400893 A BR PI0400893A BR PI0400893 A BRPI0400893 A BR PI0400893A
Authority
BR
Brazil
Prior art keywords
fructose
sucrose
dextran
oligosaccharides
obtaining
Prior art date
Application number
Other languages
Portuguese (pt)
Inventor
Francisco Maugeri Jr
Carlos Andre Veiga Burkert
Helen Treichel
Maria Isabel Rodrigues
Saartje Hernalsteens
Original Assignee
Unicamp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unicamp filed Critical Unicamp
Priority to BRPI0400893A priority Critical patent/BRPI0400893B1/en
Publication of BRPI0400893A publication Critical patent/BRPI0400893A/en
Publication of BRPI0400893B1 publication Critical patent/BRPI0400893B1/en

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)

Abstract

"PROCESSO DE OBTENçãO DE DEXTRANA CLìNICA, OLIGOSSACARìDEOS E FRUTOSE APARTIR DA SACAROSE". A presente invenção se refere a um processo de obtenção de dextrana clínica, frutose e oligossacarídeos a partir de sacarose, utilizando a enzima dextrana-sacarose de Leuconostoc mesenteroides NRRL B512 F. Os produtos citados são obtidos através de síntese enzimática, hidrólise química, fracionamento e separação de oligossacarídeos e frutose, através de colunas de adsorção, com leito de zeólita bárica, e de permeação em gel. A dextrana clínica tem diversas aplicações principalmente na indústria farmacêutica (sendo utilizada como expansor volumétrico de sangue e auxiliador da circulação sanguínea entre outros), os oligossacarídeos são muito aplicados em alimentos, como fibras solúveis e alimentos pré-bióticos, ou seja, compostos que estimulam a flora benéfica, microrganismos ditos pró-bióticos, dos intestinos de humanos e animais em geral. Também são utilizados em cosméticos, sendo cada vez maior o número de aplicações possíveis. A frutose é um produto secundário gerado durante a síntese, em que a sacarose é quebrada para a formação da dextrana, gerando a frutose livre. Devido à sua importância económica a flutose é recuperada neste processo, obtendo-se, portanto, um aproveitamento completo do açúcar utilizado."Process for obtaining clinical dextran, oligosaccharides and fructose from sucrose". The present invention relates to a process for obtaining clinical dextran, fructose and oligosaccharides from sucrose using Leuconostoc mesenteroides NRRL B512 F dextran sucrose enzyme. The products cited are obtained by enzymatic synthesis, chemical hydrolysis, fractionation and separation of oligosaccharides and fructose through adsorption columns with baric zeolite bed and gel permeation. Clinical dextran has several applications mainly in the pharmaceutical industry (being used as volumetric blood expander and aids blood circulation among others), oligosaccharides are widely applied in foods such as soluble fiber and prebiotic foods, ie compounds that stimulate beneficial flora, so-called pro-biotic microorganisms, from the intestines of humans and animals in general. They are also used in cosmetics, and the number of possible applications is increasing. Fructose is a by-product generated during synthesis in which sucrose is broken down to the formation of dextran, generating free fructose. Due to its economic importance, flutose is recovered in this process, thus obtaining a full use of the sugar used.

BRPI0400893A 2004-03-11 2004-03-11 process of obtaining clinical dextran, oligosaccharides and fructose from sucrose BRPI0400893B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI0400893A BRPI0400893B1 (en) 2004-03-11 2004-03-11 process of obtaining clinical dextran, oligosaccharides and fructose from sucrose

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0400893A BRPI0400893B1 (en) 2004-03-11 2004-03-11 process of obtaining clinical dextran, oligosaccharides and fructose from sucrose

Publications (2)

Publication Number Publication Date
BRPI0400893A true BRPI0400893A (en) 2005-11-01
BRPI0400893B1 BRPI0400893B1 (en) 2015-12-15

Family

ID=35277077

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0400893A BRPI0400893B1 (en) 2004-03-11 2004-03-11 process of obtaining clinical dextran, oligosaccharides and fructose from sucrose

Country Status (1)

Country Link
BR (1) BRPI0400893B1 (en)

Also Published As

Publication number Publication date
BRPI0400893B1 (en) 2015-12-15

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Legal Events

Date Code Title Description
B03A Publication of an application: publication of a patent application or of a certificate of addition of invention
B06F Objections, documents and/or translations needed after an examination request according art. 34 industrial property law
B06A Notification to applicant to reply to the report for non-patentiability or inadequacy of the applcation according art. 36 industrial patent law
B06A Notification to applicant to reply to the report for non-patentiability or inadequacy of the applcation according art. 36 industrial patent law
B07A Technical examination (opinion): publication of technical examination (opinion)
B09A Decision: granting
B16A Patent or certificate of addition of invention granted

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