BR9916302A - Controlled release of active agents from a chewing gum coating - Google Patents

Controlled release of active agents from a chewing gum coating

Info

Publication number
BR9916302A
BR9916302A BR9916302-0A BR9916302A BR9916302A BR 9916302 A BR9916302 A BR 9916302A BR 9916302 A BR9916302 A BR 9916302A BR 9916302 A BR9916302 A BR 9916302A
Authority
BR
Brazil
Prior art keywords
chewing gum
active agent
controlled release
coating
active agents
Prior art date
Application number
BR9916302-0A
Other languages
Portuguese (pt)
Inventor
Donald J Townsend
Henry T Tyrpin
Joo H Song
David W Record
Michael P Russel
Philip G Schnell
Original Assignee
Wrigley W M Jun Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wrigley W M Jun Co filed Critical Wrigley W M Jun Co
Publication of BR9916302A publication Critical patent/BR9916302A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/02—Apparatus specially adapted for manufacture or treatment of chewing gum
    • A23G4/025—Apparatus specially adapted for manufacture or treatment of chewing gum for coating or surface-finishing
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/064—Chewing gum characterised by the composition containing organic or inorganic compounds containing inorganic compounds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/068—Chewing gum characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/10—Chewing gum characterised by the composition containing organic or inorganic compounds characterised by the carbohydrates used, e.g. polysaccharides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/06—Chewing gum characterised by the composition containing organic or inorganic compounds
    • A23G4/12—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G4/126—Chewing gum characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing vitamins, antibiotics
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G4/00—Chewing gum
    • A23G4/18—Chewing gum characterised by shape, structure or physical form, e.g. aerated products
    • A23G4/20—Composite products, e.g. centre-filled, multi-layer, laminated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A61K9/0058—Chewing gums
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Inorganic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Confectionery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

"LIBERAçãO CONTROLADA DE AGENTES ATIVOS A PARTIR DE UM REVESTIMENTO DE GOMA DE MASCAR". Método de produção de uma goma de mascar com uma liberação controlada de agente ativo, bem como a goma de mascar assim produzida, é obtida pela modificação física das propriedades do agente ativo por revestimento e secagem. Um agente ativo é revestido por encapsulação, parcialmente revestido por aglutinação, aprisionamento por absorção, ou tratado por múltiplas etapas de encapsulação, aglutinação, e absorção. O agente ativo revestido é então co-secado e formatado em partícula para produzir um agente ativo de liberação modificada. Quando incorporado a um revestimento de goma de mascar, estas partículas liberam na boca e mascaram o amargo e outros sabores desagradáveis na boca, e são prontamente ingeridos."CONTROLLED RELEASE OF ACTIVE AGENTS FROM A GUM COATING". Method of producing a chewing gum with a controlled release of active agent, as well as the chewing gum thus produced, is obtained by physically modifying the properties of the active agent by coating and drying. An active agent is encapsulated coated, partially coated by agglutination, absorption entrapment, or treated by multiple encapsulation, agglutination, and absorption steps. The coated active agent is then co-dried and particulate to produce a modified release active agent. When incorporated into a chewing gum coating, these particles release in the mouth and mask the bitter and other unpleasant flavors in the mouth, and are readily ingested.

BR9916302-0A 1998-12-15 1999-12-10 Controlled release of active agents from a chewing gum coating BR9916302A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11238998P 1998-12-15 1998-12-15
US38921199A 1999-09-02 1999-09-02
PCT/US1999/029280 WO2000035295A1 (en) 1998-12-15 1999-12-10 Controlling release of active agents from a chewing gum coating

Publications (1)

Publication Number Publication Date
BR9916302A true BR9916302A (en) 2003-11-18

Family

ID=26809888

Family Applications (2)

Application Number Title Priority Date Filing Date
BR9916302-0A BR9916302A (en) 1998-12-15 1999-12-10 Controlled release of active agents from a chewing gum coating
BR9916304-7A BR9916304A (en) 1998-12-15 1999-12-14 Chewing gum containing active medication agents

Family Applications After (1)

Application Number Title Priority Date Filing Date
BR9916304-7A BR9916304A (en) 1998-12-15 1999-12-14 Chewing gum containing active medication agents

Country Status (6)

Country Link
EP (1) EP1139773A4 (en)
CN (1) CN1354624A (en)
AU (1) AU1937700A (en)
BR (2) BR9916302A (en)
CA (1) CA2355777A1 (en)
WO (1) WO2000035295A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1803444T3 (en) * 2002-12-20 2019-02-25 Niconovum Ab PROCEDURE FOR PREPARING A NICOTIC PARTICULATE MATERIAL WITH A CRYSTALLINE CELLULOSE (ESPECIALLY MCC)
US7201920B2 (en) 2003-11-26 2007-04-10 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse of opioid containing dosage forms
BRPI0508335B1 (en) * 2004-02-26 2019-09-03 Wrigley W M Jun Co sweets and chewing gum containing physiological cooling agents
DE102004017440A1 (en) * 2004-04-08 2005-11-03 Enthone Inc., West Haven Process for the treatment of laser-structured plastic surfaces
JP2010504931A (en) 2006-09-27 2010-02-18 ニコノヴァム エービー Use of directivity
AU2010300641B2 (en) 2009-09-30 2016-03-17 Acura Pharmaceuticals, Inc. Methods and compositions for deterring abuse
WO2011082050A1 (en) * 2009-12-30 2011-07-07 Wm. Wrigley Jr. Company Hard and crunchy confectionary coating
EP2587940B1 (en) * 2010-06-30 2014-08-06 Unilever N.V. Particles comprising hydrophobic polymer and hydrophobic phenolic compound
EP2598121B1 (en) 2010-07-28 2018-08-08 Dow Global Technologies LLC A method of controlling the release of an active ingredient from a dosage form
CN102824350B (en) * 2012-08-20 2013-08-14 安徽新和成皖南药业有限公司 Compound sulfamethoxazole dry suspension and preparation method thereof
RU2673818C2 (en) 2012-11-30 2018-11-30 Экьюра Фармасьютикалз, Инк. Self-regulated release of active pharmaceutical ingredient
GB201417163D0 (en) 2014-09-29 2014-11-12 Provost Fellows & Scholars College Of The Holy Undivided Trinity Of Queen Elizabeth Near Dublin Substituted pyrimidine derivatives useful in the treatment of autoimmune diseases
CN107923896A (en) * 2015-04-24 2018-04-17 高露洁-棕榄公司 Porous protein body as active agent carrier
CN105030716B (en) * 2015-08-06 2019-08-16 中国人民解放军军事医学科学院毒物药物研究所 Caffeinum pharmaceutical combination and preparation method thereof
WO2017040607A1 (en) 2015-08-31 2017-03-09 Acura Pharmaceuticals, Inc. Methods and compositions for self-regulated release of active pharmaceutical ingredient
WO2018147842A1 (en) * 2017-02-08 2018-08-16 Intercontinental Great Brands Llc Advanced encapsulation process for controlled release of active ingredients from a chewing gum

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3011949A (en) * 1958-06-10 1961-12-05 Anthony G Bilotti Method of promoting release of active ingredients from slab chewing gum and product
FR2345938A1 (en) * 1976-03-05 1977-10-28 Choay Patrick Chewing gum contg. xanthine stimulants or mixts. - including plant extracts e.g. tea and coffee extracts
US4452821A (en) * 1981-12-18 1984-06-05 Gerhard Gergely Confectionery product, particularly chewing gum, and process for its manufacture
US5004595A (en) * 1986-12-23 1991-04-02 Warner-Lambert Company Multiple encapsulated flavor delivery system and method of preparation
US5013716A (en) * 1988-10-28 1991-05-07 Warner-Lambert Company Unpleasant taste masking compositions and methods for preparing same
US4997659A (en) * 1989-03-28 1991-03-05 The Wm. Wrigley Jr. Company Alitame stability in chewing gum by encapsulation
US4978537A (en) * 1989-04-19 1990-12-18 Wm. Wrigley Jr. Company Gradual release structures for chewing gum
DK365389D0 (en) * 1989-07-24 1989-07-24 Fertin Lab As ANTIFUNGAL CHEMICAL GUM PREPARATION
US5270061A (en) * 1992-03-26 1993-12-14 Wm. Wrigley Jr. Company Dual composition hard coated gum with improved shelf life
US5380530A (en) * 1992-12-29 1995-01-10 Whitehill Oral Technologies Oral care composition coated gum
WO1997004662A1 (en) * 1995-07-26 1997-02-13 Wm. Wrigley Jr. Company Use of encapsulated aspartic acid sweeteners in coating syrups for coated pellet chewing gums
WO1998023165A1 (en) * 1996-11-27 1998-06-04 Wm. Wrigley Jr. Company Method of controlling release of caffeine in chewing gum and gum produced thereby

Also Published As

Publication number Publication date
WO2000035295A1 (en) 2000-06-22
CA2355777A1 (en) 2000-06-22
CN1354624A (en) 2002-06-19
EP1139773A1 (en) 2001-10-10
EP1139773A4 (en) 2002-06-12
AU1937700A (en) 2000-07-03
BR9916304A (en) 2001-11-13

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Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion)
B15K Others concerning applications: alteration of classification

Free format text: ALTERADO DE INT.CL: A61K 9/68; A23G 4/06

Ipc: A61K 9/68 (2008.01), A23G 4/06 (2008.01)

B15V Prolongation of time limit allowed

Free format text: DEVOLUCAO DE PRAZO CONCEDIDA - RECONHECIDO O OBSTACULO ADMINISTRATIVO E DEVOLVIDO O PRAZO DE 15 DIAS, NOS TERMOS DO ARTIGO 221 PARAGRAFO 2O DA LPI E DA RESOLUCAO 116/04.

B09B Decision: refusal

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B09B Decision: refusal

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