BR9916012A - Seringa sem agulha com cartucho preenchido - Google Patents
Seringa sem agulha com cartucho preenchidoInfo
- Publication number
- BR9916012A BR9916012A BR9916012-9A BR9916012A BR9916012A BR 9916012 A BR9916012 A BR 9916012A BR 9916012 A BR9916012 A BR 9916012A BR 9916012 A BR9916012 A BR 9916012A
- Authority
- BR
- Brazil
- Prior art keywords
- cartridge
- valve
- nozzle
- needle
- disposed
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2459—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
- A61M2005/2462—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst by displacing occluding plugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/28—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle
- A61M5/285—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened
- A61M5/286—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
- A61M2005/287—Syringe ampoules or carpules, i.e. ampoules or carpules provided with a needle with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst by displacing occluding plugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3103—Leak prevention means for distal end of syringes, i.e. syringe end for mounting a needle
- A61M2005/3106—Plugs for syringes without needle
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3123—Details having air entrapping or venting means, e.g. purging channels in pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
- A61M5/2459—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened upon internal pressure increase, e.g. pierced or burst
Abstract
"SERINGA SEM AGULHA COM CARTUCHO PREENCHIDO". Um cartucho e uma montagem de bocal para uso em um sistema de injeção agulha é oferecido. A montagem inclui um cartucho (12 ) tendo um êmbolo (24 ) disposto a uma extremidade traseira do mesmo incluindo uma entrada (21) em uma parte dianteira do mesmo com uma válvula de saída que pode ser deslocada (46) inicialmente disposta dentro da entrada (21), sendo a válvula de saída (46) feita de material resiliente tendo, pelo menos, um canal axial (56,62) definido na parte traseira e dianteira do mesmo entre a qual está disposto um corpo de válvula sem canal (58) . Um bocal (14) para receber o cartucho (12); o bocal (14) definindo uma parte receptora traseira de cartucho e incluindo uma parte dianteira delimitando e definindo uma superfície de apoio de válvula (48) com um orifício de injeção (52) definido lá e uma parte recessiva (50) sendo configurada para receber a válvula (46) quando a válvula (46) for deslocada para uma posição dianteira de tal forma que a válvula (46) esteja disposta contra a superfície de apoio de válvula (48) de forma que a parte interna do cartucho (12) tenha acesso de fluido ao orifício (52) via os canais axiais (56 , 62) e ao redor do corpo de válvula (46). Um selo (22) disposto entre o cartucho (12) e o bocal (14) adjacente às partes dianteiras do mesmo para, pelo menos, reduzir o vazamento da injeção entre eles.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/207,398 US6132395A (en) | 1998-12-08 | 1998-12-08 | Needleless syringe with prefilled cartridge |
PCT/US1999/028734 WO2000033899A1 (en) | 1998-12-08 | 1999-12-03 | Needleless syringe with prefilled cartridge |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9916012A true BR9916012A (pt) | 2002-07-09 |
Family
ID=22770391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9916012-9A BR9916012A (pt) | 1998-12-08 | 1999-12-03 | Seringa sem agulha com cartucho preenchido |
Country Status (5)
Country | Link |
---|---|
US (1) | US6132395A (pt) |
JP (1) | JP4226787B2 (pt) |
BR (1) | BR9916012A (pt) |
CA (1) | CA2353948C (pt) |
WO (1) | WO2000033899A1 (pt) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5730723A (en) | 1995-10-10 | 1998-03-24 | Visionary Medical Products Corporation, Inc. | Gas pressured needle-less injection device and method |
US6264629B1 (en) * | 1998-11-18 | 2001-07-24 | Bioject, Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
US6783509B1 (en) | 1998-11-18 | 2004-08-31 | Bioject Inc. | Single-use needle-less hypodermic jet injection apparatus and method |
US6406455B1 (en) * | 1998-12-18 | 2002-06-18 | Biovalve Technologies, Inc. | Injection devices |
US7060048B1 (en) * | 1999-04-16 | 2006-06-13 | Powerject Research Limited | Needleless syringe |
US7074210B2 (en) * | 1999-10-11 | 2006-07-11 | Felton International, Inc. | Universal protector cap with auto-disable features for needle-free injectors |
US7887506B1 (en) * | 1999-11-23 | 2011-02-15 | Pulse Needlefree Systems, Inc. | Safety mechanism to prevent accidental patient injection and methods of same |
ATE501751T1 (de) * | 2000-01-07 | 2011-04-15 | Valeritas Inc | Injektionsvorrichtung |
ATE499961T1 (de) * | 2000-03-23 | 2011-03-15 | Antares Pharma Inc | Einwegdruckstrahlinjektor |
FR2809626B1 (fr) * | 2000-05-30 | 2003-03-07 | Poudres & Explosifs Ste Nale | Seringue sans aiguille avec membrane d'isolation d'un ejecteur multiconduit |
DE10034270A1 (de) * | 2000-07-14 | 2002-02-14 | Disetronic Licensing Ag | Vorratsbehältnis mit einer Dosiereinrichtung zur dosierten Abgabe eines injizierbaren Produkts an ein Injektionsgerät |
KR20030071780A (ko) | 2000-11-30 | 2003-09-06 | 바이오밸브 테크놀로지스, 인코포레이티드 | 주입기 |
GB0100756D0 (en) | 2001-01-11 | 2001-02-21 | Powderject Res Ltd | Needleless syringe |
US6471669B2 (en) | 2001-03-05 | 2002-10-29 | Bioject Medical Technologies Inc. | Disposable needle-free injection apparatus and method |
US6645170B2 (en) * | 2001-03-05 | 2003-11-11 | Bioject Medical Technologies, Inc. | Simplified disposable needle-free injection apparatus and method |
US6500239B2 (en) | 2001-03-14 | 2002-12-31 | Penjet Corporation | System and method for removing dissolved gas from a solution |
US6613010B2 (en) | 2001-04-13 | 2003-09-02 | Penjet Corporation | Modular gas-pressured needle-less injector |
EP1252906A1 (en) * | 2001-04-26 | 2002-10-30 | Fada Italia, S.P.A. | Improved disposable pre-filled syringe |
WO2002087663A2 (en) | 2001-04-27 | 2002-11-07 | Penjet Corporation | Method and apparatus for filling or refilling a needle-less injector |
DE10137962A1 (de) * | 2001-08-07 | 2003-02-20 | Roesch Ag Medizintechnik | Ampulle für eine Injektionseinrichtung |
US6824526B2 (en) | 2001-10-22 | 2004-11-30 | Penjet Corporation | Engine and diffuser for use with a needle-less injector |
US6607510B2 (en) | 2001-11-09 | 2003-08-19 | Bioject Medical Technologies Inc. | Disposable needle-free injection apparatus and method |
AU2003209095A1 (en) | 2002-02-11 | 2003-09-04 | Antares Pharma, Inc. | Intradermal injector |
EP1476211B1 (en) * | 2002-02-15 | 2015-06-24 | Antares Pharma, Inc. | Injector with bypass channel |
US7238167B2 (en) * | 2002-06-04 | 2007-07-03 | Bioject Inc. | Needle-free injection system |
US6676630B2 (en) | 2002-06-04 | 2004-01-13 | Bioject Medical Technologies, Inc. | Needle-free injection system |
US7156823B2 (en) * | 2002-06-04 | 2007-01-02 | Bioject Inc. | High workload needle-free injection system |
BR0314111A (pt) * | 2002-09-12 | 2005-07-26 | Childrens Hosp Medical Center | Método e dispositivo para injeção de medicação sem dor |
US6883222B2 (en) * | 2002-10-16 | 2005-04-26 | Bioject Inc. | Drug cartridge assembly and method of manufacture |
US6935384B2 (en) * | 2003-02-19 | 2005-08-30 | Bioject Inc. | Needle-free injection system |
FR2853837B1 (fr) * | 2003-04-16 | 2006-01-13 | Crossject | Dispositif de liaison d'un reservoir de principe actif sur une buse d'injection dans un dispositif d'injection dudit principe actif |
BRPI0414321B8 (pt) | 2003-09-22 | 2021-06-22 | Baxter Healthcare Sa | esterilização à alta pressão para esterilização final de preparações farmacêuticas e produtos médicos |
US7670314B2 (en) * | 2004-02-17 | 2010-03-02 | Children's Hospital Medical Center | Injection device for administering a vaccine |
US7717874B2 (en) * | 2004-05-28 | 2010-05-18 | Bioject, Inc. | Needle-free injection system |
EP2532378B1 (en) | 2004-12-01 | 2016-04-27 | AcuShot, Inc. | Needle-free injector |
DE102004059126B4 (de) * | 2004-12-08 | 2014-01-16 | Roche Diagnostics Gmbh | Adapter für Injektionsgerät |
US8262605B2 (en) * | 2004-12-09 | 2012-09-11 | Ams Research Corporation | Needleless delivery systems |
EP3495009B1 (en) | 2005-01-24 | 2021-12-08 | Antares Pharma, Inc. | An injector with prefilled syringe |
US8998881B2 (en) | 2005-08-10 | 2015-04-07 | Alza Corporation | Method for delivering drugs to tissue under microjet propulsion |
US20090312696A1 (en) * | 2005-12-28 | 2009-12-17 | Copa Vincent G | Devices, Systems, and Related Methods for Delivery of Fluid to Tissue |
CN101374562B (zh) * | 2006-01-31 | 2011-09-14 | 诺沃-诺迪斯克有限公司 | 用于预填充的医疗射流注射装置的密封件 |
US8251947B2 (en) | 2006-05-03 | 2012-08-28 | Antares Pharma, Inc. | Two-stage reconstituting injector |
US9233206B2 (en) * | 2006-08-30 | 2016-01-12 | Arthur Harris | Continuous feed hypodermic syringe with self contained cartridge dispenser |
US7942845B2 (en) * | 2006-09-19 | 2011-05-17 | Bioject, Inc. | Needle-free injector and process for providing serial injections |
FR2905872B1 (fr) * | 2006-09-19 | 2008-12-19 | Crossjet | Dispositif d'injection sans aiguille muni d'un reservoir securise |
US7547293B2 (en) | 2006-10-06 | 2009-06-16 | Bioject, Inc. | Triggering mechanism for needle-free injector |
US20080119823A1 (en) | 2006-11-21 | 2008-05-22 | Crank Justin M | Injection Tube for Jet Injection Device |
US8382713B2 (en) * | 2006-12-11 | 2013-02-26 | Kenergy Scientific, Inc. | Drug delivery device and methodology |
US7744563B2 (en) | 2007-02-23 | 2010-06-29 | Bioject, Inc. | Needle-free injection devices and drug delivery systems therefor |
GB0708758D0 (en) | 2007-05-04 | 2007-06-13 | Powderject Res Ltd | Particle cassettes and process thereof |
US8617099B2 (en) * | 2007-11-26 | 2013-12-31 | Bioject Inc. | Injection device plunger auto-disable |
US20090137949A1 (en) * | 2007-11-26 | 2009-05-28 | Bioject Inc. | Needle-free injection device with nozzle auto-disable |
CN103041478B (zh) | 2008-04-10 | 2015-01-21 | 松下健康医疗控股株式会社 | 给药装置 |
EP2318075B1 (en) | 2008-08-05 | 2019-05-22 | Antares Pharma, Inc. | Multiple dosage injector |
JP4439577B1 (ja) * | 2008-11-28 | 2010-03-24 | 株式会社アルテ | 容器兼用注射器 |
US8579865B2 (en) | 2009-03-20 | 2013-11-12 | Antares Pharma, Inc. | Hazardous agent injection system |
US9867945B2 (en) * | 2010-08-06 | 2018-01-16 | Sanofi-Aventis Deutschland Gmbh | Cartridge holder and method for assembling a cartridge unit for a drug delivery device |
CN103140249A (zh) * | 2010-08-06 | 2013-06-05 | 赛诺菲-安万特德国有限公司 | 用于在保持器中保持盒体的方法和系统 |
US8496619B2 (en) | 2011-07-15 | 2013-07-30 | Antares Pharma, Inc. | Injection device with cammed ram assembly |
US9220660B2 (en) | 2011-07-15 | 2015-12-29 | Antares Pharma, Inc. | Liquid-transfer adapter beveled spike |
EP3400982B1 (en) * | 2011-07-19 | 2021-06-16 | Sanofi-Aventis Deutschland GmbH | Cartridge holder for a drug delivery device |
US9950125B2 (en) | 2012-04-06 | 2018-04-24 | Antares Pharma, Inc. | Needle assisted jet injection administration of testosterone compositions |
WO2013169804A1 (en) | 2012-05-07 | 2013-11-14 | Antares Pharma, Inc. | Needle assisted jet injection device having reduced trigger force |
PT3659647T (pt) | 2013-02-11 | 2024-03-27 | Antares Pharma Inc | Dispositivo de injeção a jato auxiliado por agulha tendo força de gatilho reduzida |
ES2742046T3 (es) | 2013-03-11 | 2020-02-12 | Antares Pharma Inc | Inyector de dosis con sistema de piñón |
FR3058718B1 (fr) | 2016-11-15 | 2020-11-06 | Crossject | Procede de trempe a l’air d’un corps creux en verre allonge comprenant un percage axial |
EP3706834A1 (de) * | 2017-11-10 | 2020-09-16 | CC - Pharma GmbH | Verfahren und vorrichtung zum nadellosen injizieren von flüssigkeit in ein substrat |
EP3632817A1 (en) | 2018-10-02 | 2020-04-08 | Sulzer Mixpac AG | Cartridge, method of making a cartridge and method of using a cartridge |
WO2021101794A1 (en) * | 2019-11-19 | 2021-05-27 | Eli Lilly And Company | Drug delivery systems including displaceable closures |
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US3941128A (en) * | 1970-11-10 | 1976-03-02 | Affiliated Hospital Products, Inc. | Fluid dispensing arrangement |
US3729031A (en) * | 1971-12-06 | 1973-04-24 | Mpl Inc | Liquid dispenser and plunger and method and apparatus for filling same |
US3940003A (en) * | 1974-05-07 | 1976-02-24 | Pharmaco, Inc. | Safety cap for medicament vial having puncturable seal |
US4592745A (en) * | 1984-02-29 | 1986-06-03 | Novo Industri A/S | Dispenser |
US4662878A (en) * | 1985-11-13 | 1987-05-05 | Patents Unlimited Ltd. | Medicine vial adaptor for needleless injector |
EP0250022A3 (en) * | 1986-06-17 | 1988-06-22 | SICIM SpA | Portable endermic injector |
US4713061A (en) * | 1986-07-14 | 1987-12-15 | Survival Technology, Inc. | Cartridge with universal plastic hub |
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US4790824A (en) * | 1987-06-19 | 1988-12-13 | Bioject, Inc. | Non-invasive hypodermic injection device |
AU595096B2 (en) * | 1988-02-10 | 1990-03-22 | Astra Pharmaceuticals Pty Ltd | Plastic cartridge and syringe |
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US5049128A (en) * | 1990-02-06 | 1991-09-17 | Duquette Irene A | Valved infusion port |
EP0518416A1 (en) * | 1991-06-13 | 1992-12-16 | Duphar International Research B.V | Injection device |
DK134691D0 (da) * | 1991-07-12 | 1991-07-12 | Novo Nordisk As | Apparat |
GB9212742D0 (en) * | 1992-06-16 | 1992-07-29 | Sterimatic Holdings Ltd | Syringe or blood collection system |
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US5405333A (en) * | 1992-12-28 | 1995-04-11 | Richmond; Frank M. | Liquid medicament bag with needleless connector fitting using boat assembly |
US5364386A (en) * | 1993-05-05 | 1994-11-15 | Hikari Seiyaku Kabushiki Kaisha | Infusion unit |
US5472022A (en) * | 1993-11-02 | 1995-12-05 | Genentech, Inc. | Injection pen solution transfer apparatus and method |
US5716348A (en) * | 1995-10-19 | 1998-02-10 | Meridian Medical Technologies, Inc. | Anti-coring needle |
GB9607549D0 (en) * | 1996-04-11 | 1996-06-12 | Weston Medical Ltd | Spring-powered dispensing device |
-
1998
- 1998-12-08 US US09/207,398 patent/US6132395A/en not_active Expired - Lifetime
-
1999
- 1999-12-03 CA CA002353948A patent/CA2353948C/en not_active Expired - Fee Related
- 1999-12-03 JP JP2000586389A patent/JP4226787B2/ja not_active Expired - Fee Related
- 1999-12-03 WO PCT/US1999/028734 patent/WO2000033899A1/en active Application Filing
- 1999-12-03 BR BR9916012-9A patent/BR9916012A/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JP4226787B2 (ja) | 2009-02-18 |
US6132395A (en) | 2000-10-17 |
JP2002531227A (ja) | 2002-09-24 |
CA2353948A1 (en) | 2000-06-15 |
CA2353948C (en) | 2008-05-20 |
WO2000033899A1 (en) | 2000-06-15 |
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