BR9912519A - Stabilized variants of streptomyces subtilisin inhibitor - Google Patents

Stabilized variants of streptomyces subtilisin inhibitor

Info

Publication number
BR9912519A
BR9912519A BR9912519-6A BR9912519A BR9912519A BR 9912519 A BR9912519 A BR 9912519A BR 9912519 A BR9912519 A BR 9912519A BR 9912519 A BR9912519 A BR 9912519A
Authority
BR
Brazil
Prior art keywords
variants
subtilisin inhibitor
streptomyces subtilisin
compositions
ssi
Prior art date
Application number
BR9912519-6A
Other languages
Portuguese (pt)
Inventor
Charles Winston Saunders
Paul Elliott Correa
Yiping Sun
Mark Donald Bauer
Donn Nelton Rubingh
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of BR9912519A publication Critical patent/BR9912519A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/26Organic compounds containing nitrogen
    • C11D3/33Amino carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/37Polymers
    • C11D3/3703Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • C11D3/3719Polyamides or polyimides
    • CCHEMISTRY; METALLURGY
    • C11ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11DDETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16Organic compounds
    • C11D3/38Products with no well-defined composition, e.g. natural products
    • C11D3/386Preparations containing enzymes, e.g. protease or amylase
    • C11D3/38618Protease or amylase in liquid compositions only

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Patente de Invenção: <B>"VARIANTES ESTABILIZADAS DE INIBIDOR DE SUBTILISINA DE STREPTOMYCES"<D>. A presente invenção refere-se a variantes de inibidor de subtilisina de Streptomyces (SSI) e àqueles inibidores que têm homologia com SSI. Tais variantes são úteis em associação com enzimas, particularmente com proteases, em composições para limpeza e em composições para higiene pessoal. As variantes compreendem uma substituição de aminoácido na posição 63 correspondente a SSI. Tais variantes fornecem maior estabilidade proteolítica em composições para limpeza e em composições para higiene pessoal. A presente invenção também refere-se a composições para limpeza e a composições para higiene pessoal que compreendem as presentes variantes, assim como a genes que codificam as variantes.Invention Patent: <B> "STABILIZED VARIABLES OF STREPTOMYCES SUBTILISIN INHIBITOR" <D>. The present invention relates to Streptomyces subtilisin inhibitor (SSI) variants and to those inhibitors that have homology to SSI. Such variants are useful in association with enzymes, particularly with proteases, in cleaning compositions and in personal hygiene compositions. The variants comprise an amino acid substitution at position 63 corresponding to SSI. Such variants provide greater proteolytic stability in cleaning compositions and in personal hygiene compositions. The present invention also relates to cleaning compositions and personal hygiene compositions that comprise the present variants, as well as to genes encoding the variants.

BR9912519-6A 1998-06-26 1999-07-07 Stabilized variants of streptomyces subtilisin inhibitor BR9912519A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9191198P 1998-06-26 1998-06-26
PCT/US1999/015246 WO2000001826A2 (en) 1998-06-26 1999-07-07 Stabilized variants of streptomyces subtilisin inhibitor

Publications (1)

Publication Number Publication Date
BR9912519A true BR9912519A (en) 2001-05-02

Family

ID=22230265

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9912519-6A BR9912519A (en) 1998-06-26 1999-07-07 Stabilized variants of streptomyces subtilisin inhibitor

Country Status (8)

Country Link
EP (1) EP1093518A2 (en)
JP (1) JP2004500007A (en)
CN (1) CN1316000A (en)
AR (1) AR020106A1 (en)
AU (1) AU4862399A (en)
BR (1) BR9912519A (en)
CA (1) CA2332564A1 (en)
WO (1) WO2000001826A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DZ3349A1 (en) 2000-07-28 2002-02-07 Henkel Kgaa NEW AMYLOLYTIC ENZYME FROM BACILLUS SP. A 7-7 (DSM 12368) AND WASHING AND CLEANING PRODUCTS CONTAINING SAID AMYLOLYTIC ENZYME
WO2002044350A2 (en) 2000-11-28 2002-06-06 Henkel Kommanditgesellschaft Auf Aktien Cyclodextrin glucanotransferase (cgtase), obtained from bacillus agaradherens (dsm 9948) and detergents and cleaning agents containing said novel cyclodextrin glucanotransferase
WO2003041680A1 (en) * 2001-11-13 2003-05-22 The Procter & Gamble Company Topical compositions containing enzymes stabilized with inhibitors
MXPA04004478A (en) * 2001-11-13 2004-08-11 Procter & Gamble Compositions containing enzymes stabilized with certain osmo-protectants and methods for using such compositions in personal care.
DE10360805A1 (en) 2003-12-23 2005-07-28 Henkel Kgaa New alkaline protease and detergents containing this novel alkaline protease
WO2008051491A2 (en) 2006-10-20 2008-05-02 Danisco Us, Inc. Genencor Division Polyol oxidases
DE102007032111B4 (en) 2007-07-09 2017-07-20 Henkel Ag & Co. Kgaa New proteases and detergents and cleaning agents containing these proteases
DE102007036756A1 (en) 2007-08-03 2009-02-05 Henkel Ag & Co. Kgaa New proteases and detergents and cleaners containing these new proteases
JP5953312B2 (en) * 2011-10-12 2016-07-20 三洋化成工業株式会社 Proteinaceous protease inhibitor and protein solution and detergent composition containing the same
DE102022205593A1 (en) * 2022-06-01 2023-12-07 Henkel Ag & Co. Kgaa DETERGENT AND CLEANING AGENTS WITH IMPROVED ENZYME STABILITY

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0929577B1 (en) * 1996-09-24 2003-06-04 The Procter & Gamble Company Stabilized proteinaceous protease inhibitors and variants thereof

Also Published As

Publication number Publication date
AU4862399A (en) 2000-01-24
EP1093518A2 (en) 2001-04-25
AR020106A1 (en) 2002-04-10
CA2332564A1 (en) 2000-01-13
WO2000001826A3 (en) 2000-04-06
WO2000001826A2 (en) 2000-01-13
JP2004500007A (en) 2004-01-08
CN1316000A (en) 2001-10-03

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Legal Events

Date Code Title Description
B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 6A, 7A E 8A ANUIDADES

B08K Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87)

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007.