BR9911211A - Método para indução de apoptose em células - Google Patents
Método para indução de apoptose em célulasInfo
- Publication number
- BR9911211A BR9911211A BR9911211-6A BR9911211A BR9911211A BR 9911211 A BR9911211 A BR 9911211A BR 9911211 A BR9911211 A BR 9911211A BR 9911211 A BR9911211 A BR 9911211A
- Authority
- BR
- Brazil
- Prior art keywords
- cells
- inducing apoptosis
- gene
- overexpressed
- instance
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
"MéTODO PARA INDUçãO DE APOPTOSE EM CéLULAS". A presente invenção refere-se a um método para acionamento de apoptose, onde o gene C1D é super expresso nas células, de modo particular, em células tumorais. Isto ocorre, por exemplo, através da introdução de correspondentes constructos de expressão nas células ou através da estimulação exógena da expressão dos genes C1D da própria célula.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19824811A DE19824811C2 (de) | 1998-06-03 | 1998-06-03 | Verfahren zur Auslösung von Apoptose in Zellen |
PCT/DE1999/001684 WO1999063071A2 (de) | 1998-06-03 | 1999-06-02 | Verfahren zur auslösung von apoptose in zellen |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9911211A true BR9911211A (pt) | 2002-06-11 |
Family
ID=7869786
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9911211-6A BR9911211A (pt) | 1998-06-03 | 1999-06-02 | Método para indução de apoptose em células |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1121426B1 (pt) |
JP (1) | JP2002517192A (pt) |
CN (1) | CN1320163A (pt) |
AT (1) | ATE264387T1 (pt) |
AU (1) | AU754686B2 (pt) |
BR (1) | BR9911211A (pt) |
CA (1) | CA2330227A1 (pt) |
DE (2) | DE19824811C2 (pt) |
WO (1) | WO1999063071A2 (pt) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002042322A2 (en) * | 2000-11-21 | 2002-05-30 | Lion Bioscience Ag | Mammalian nuclear receptor cofactors cf7 and cf8 and methods of use |
DE10225394A1 (de) * | 2002-06-07 | 2003-12-24 | Deutsches Krebsforsch | Verfahren zur Auslösung von Apoptose in Zellen durch Erhöhung des C1D-Spiegels und Hemmung des Abbaus von C1D |
-
1998
- 1998-06-03 DE DE19824811A patent/DE19824811C2/de not_active Expired - Fee Related
-
1999
- 1999-06-02 CN CN99808352A patent/CN1320163A/zh active Pending
- 1999-06-02 CA CA002330227A patent/CA2330227A1/en not_active Abandoned
- 1999-06-02 AU AU51528/99A patent/AU754686B2/en not_active Ceased
- 1999-06-02 JP JP2000552267A patent/JP2002517192A/ja active Pending
- 1999-06-02 EP EP99936433A patent/EP1121426B1/de not_active Expired - Lifetime
- 1999-06-02 BR BR9911211-6A patent/BR9911211A/pt not_active IP Right Cessation
- 1999-06-02 DE DE59909197T patent/DE59909197D1/de not_active Expired - Fee Related
- 1999-06-02 AT AT99936433T patent/ATE264387T1/de not_active IP Right Cessation
- 1999-06-02 WO PCT/DE1999/001684 patent/WO1999063071A2/de not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
DE19824811C2 (de) | 2000-10-12 |
DE19824811A1 (de) | 1999-12-09 |
WO1999063071A3 (de) | 2001-06-07 |
CA2330227A1 (en) | 1999-12-09 |
AU754686B2 (en) | 2002-11-21 |
DE59909197D1 (de) | 2004-05-19 |
ATE264387T1 (de) | 2004-04-15 |
CN1320163A (zh) | 2001-10-31 |
EP1121426A2 (de) | 2001-08-08 |
AU5152899A (en) | 1999-12-20 |
WO1999063071A2 (de) | 1999-12-09 |
EP1121426B1 (de) | 2004-04-14 |
JP2002517192A (ja) | 2002-06-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP1507005A3 (en) | Antisense modulation of BCL-X expression | |
IL112539A0 (en) | Pyrimidine derivatives and their preparation | |
EP1117672A4 (en) | ANTISENSE MODULATION OF THE SURVIVIN EXPRESSION | |
MXPA01010588A (es) | Medicamentos que contienen de la cinasa humana regulada por el volumen celular h-sgk. | |
MX9801264A (es) | Control de la expresion del gen de cd44 para uso terapeutico. | |
EP1123414A4 (en) | ANTISENSE MODULATION OF THE EXPRESSION OF INTEGRIN ALPHA 4 | |
ATE275956T1 (de) | Veränderung der dns methyltransferase durch kombinationstherapie | |
WO2003083080A3 (en) | Mixed- cell gene therapy | |
UA29466C2 (uk) | Фармацевтична композиція з антипухлинною активністю | |
BR0008788A (pt) | Sequencias anti-sentido antitumor dirigidas contra componentes r1 e r2 de ribonucleotìdeo reductase | |
AU7548500A (en) | Compositions and methods for inhibiting g2 cell cycle arrest and sensitizing cells to dna damaging agents | |
ES2187648T3 (es) | Metodo para la administracion de farmacos para terapia genica. | |
GB9825096D0 (en) | Cells,culture methods and their uses | |
WO2003105755A3 (en) | ANTISENSE MODULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR C (VEGF-C) EXPRESSION | |
WO2003104397A3 (en) | ANTISENSE MODULATION OF PROTEIN KINASE GR 6 EXPRESSION | |
TR200101693T2 (tr) | Lemfotoksin (LT) sentezlenme yolunun inhibitörleri kullanılarak foliküler lemfomaların tedavisi. | |
BR9911211A (pt) | Método para indução de apoptose em células | |
WO2004003152A3 (en) | Sos1 inhibitors | |
AU2606000A (en) | Antisense modulation of x-linked inhibitor of apoptosis expression | |
BR0313550A (pt) | modulação "antisense" da expressão de sintetase 1 de acil-coa | |
PT1064265E (pt) | Sintese de 3-amino-2-cloro-4-metilpiridina a partir de malononitrilo e acetona | |
WO2003062197A3 (en) | Nek2 inhibitors | |
WO2003106645A3 (en) | ANTISENSE MODULATION OF SMRT COREPRESSOR EXPRESSION | |
WO2003105754A3 (en) | ANTISENSE MODULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR B (VEGF-B) EXPRESSION | |
DE69840986D1 (de) | DNA Fragmente die das Biotin Synthasegen enthalten und deren Verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 5,6,7 E 8A ANUIDADES. |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1911 DE 21/08/2007. |