BR9909095A - Peritoneal dialysis solution containing modified icodextrins - Google Patents
Peritoneal dialysis solution containing modified icodextrinsInfo
- Publication number
- BR9909095A BR9909095A BR9909095-3A BR9909095A BR9909095A BR 9909095 A BR9909095 A BR 9909095A BR 9909095 A BR9909095 A BR 9909095A BR 9909095 A BR9909095 A BR 9909095A
- Authority
- BR
- Brazil
- Prior art keywords
- peritoneal dialysis
- containing modified
- dialysis solution
- solution containing
- glucitols
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- External Artificial Organs (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicinal Preparation (AREA)
Abstract
Patente de Invenção: <B>"SOLUçãO DE DIáLISE PERITONEAL CONTENDO ICODEXTRINAS MODIFICADAS"<D>. A presente invenção proporciona uma solução de diálise peritoneal que contém agentes osmóticos estáveis a calor tais como D-glucitóis, ácidos glucónicos e alquilglicosídeos produzidos pela redução, oxidação ou glicosilação de icodextrina, respectivamente. Como resultado, agentes osmóticos que são estáveis sob condições de autoclave ou de esterilização por calor são proporcionados os quais reduzem a quantidade de materiais bioincompatíveis nas soluções de diálise peritoneal esterilizadas. Métodos de preparação de D-glucitóis, ácidos glucónicos e alquilglicosídeos são apresentados.Invention Patent: <B> "SOLUTION OF PERITONEAL DIALYSIS CONTAINING MODIFIED ICODEXTRINES" <D>. The present invention provides a peritoneal dialysis solution that contains heat stable osmotic agents such as D-glucitols, gluconic acids and alkylglycosides produced by the reduction, oxidation or glycosylation of icodextrin, respectively. As a result, osmotic agents that are stable under conditions of autoclave or heat sterilization are provided which reduce the amount of bioincompatible materials in sterile peritoneal dialysis solutions. Methods of preparing D-glucitols, gluconic acids and alkylglycosides are presented.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/206,063 US6770148B1 (en) | 1998-12-04 | 1998-12-04 | Peritoneal dialysis solution containing modified icodextrins |
PCT/US1999/027456 WO2000033851A1 (en) | 1998-12-04 | 1999-11-18 | Peritoneal dialysis solution containing modified icodextrins |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9909095A true BR9909095A (en) | 2000-12-05 |
Family
ID=22764822
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9909095-3A BR9909095A (en) | 1998-12-04 | 1999-11-18 | Peritoneal dialysis solution containing modified icodextrins |
Country Status (19)
Country | Link |
---|---|
US (3) | US6770148B1 (en) |
EP (1) | EP1051183B1 (en) |
JP (3) | JP4338317B2 (en) |
KR (1) | KR100597931B1 (en) |
CN (1) | CN1150903C (en) |
AR (1) | AR021515A1 (en) |
AT (1) | ATE356627T1 (en) |
AU (1) | AU762933B2 (en) |
BR (1) | BR9909095A (en) |
CA (1) | CA2319561A1 (en) |
CO (1) | CO5150157A1 (en) |
DE (1) | DE69935498T2 (en) |
DK (1) | DK1051183T3 (en) |
ES (1) | ES2284281T3 (en) |
HK (1) | HK1036014A1 (en) |
ID (1) | ID27897A (en) |
MX (1) | MXPA00008653A (en) |
TW (1) | TW555561B (en) |
WO (1) | WO2000033851A1 (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19955578C1 (en) * | 1999-11-18 | 2001-09-06 | Fresenius Medical Care De Gmbh | Multi-chamber container, with glucose concentrate compartment and hydrochloric acid concentrate compartment |
DE10237442B4 (en) | 2002-08-16 | 2004-08-19 | Fresenius Kabi Deutschland Gmbh | Highly branched, low substituted starch products |
US20040121982A1 (en) * | 2002-12-20 | 2004-06-24 | Leo Martis | Biocompatible dialysis fluids containing icodextrins |
US7118857B2 (en) * | 2004-02-27 | 2006-10-10 | Baxter International Inc. | Methods and compositions for detection of microbial contaminants in peritoneal dialysis solutions |
US20050276868A1 (en) * | 2004-06-10 | 2005-12-15 | Bart Degreve | Bicarbonate-based peritoneal dialysis solutions |
US8252333B2 (en) * | 2006-01-26 | 2012-08-28 | Jorge Cueto-Garcia | Biodegradable, non-toxic biological adhesive for use in abdominal surgery |
US20090236284A1 (en) * | 2008-03-20 | 2009-09-24 | Baxter International Inc. | Removal of substances in dialysis solutions and dialysis components by ion exchange adsorption |
FR2945043B1 (en) * | 2009-04-30 | 2019-07-26 | Roquette Freres | PROCESS FOR PURIFYING GLUCOSE POLYMERS FOR PERITONEAL DIALYSIS SOLUTIONS |
DE102010012183A1 (en) * | 2010-03-19 | 2011-09-22 | Fresenius Medical Care Deutschland Gmbh | Esterified polysaccharide osmotica |
CA2826897A1 (en) | 2011-02-08 | 2012-08-16 | Jorge Cueto Garcia | Biological thixotropic adhesive for use in the human body internal cavities |
CA2839460C (en) | 2011-06-24 | 2017-08-22 | Richard W.C. LO | Multi-container systems and uses thereof |
DE102011112526A1 (en) * | 2011-09-07 | 2013-03-07 | Fresenius Medical Care Deutschland Gmbh | Pharmaceutical composition containing carboxylated starch |
MX350080B (en) | 2013-10-02 | 2017-08-25 | Pebisut De Mexico S A De C V | Anti-inflammatory composition for aiding and promoting the healing of chronic ulcerative lesions. |
WO2016066672A1 (en) * | 2014-10-31 | 2016-05-06 | Fresenius Medical Care Deutschland Gmbh | Pharmaceutical compositions containing steviosides |
FR3055898B1 (en) * | 2016-09-15 | 2018-11-02 | Roquette Freres | NOVEL GLUCOSE POLYMERS FOR PERITONEAL DIALYSIS |
Family Cites Families (73)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3878664A (en) * | 1972-11-27 | 1975-04-22 | Cybersol | Process for producing a therapeutic composition |
US3993751A (en) * | 1972-11-27 | 1976-11-23 | Cybersol, Inc. | Process for stabilizing therapeutic compositions and article |
CA1017249A (en) * | 1973-12-19 | 1977-09-13 | Chemo Drug Company | Injectable electrolyte solutions |
US3974034A (en) * | 1975-09-12 | 1976-08-10 | Cpc International Inc. | Malto-dextrins of improved stability prepared by enzymatic hydrolysis of oxidized starch |
JPS54138121A (en) | 1978-04-19 | 1979-10-26 | Nikkiso Co Ltd | Continuous production of artificial kidney dyalising solution |
DE2929871A1 (en) | 1979-07-24 | 1981-01-29 | Gambro Dialysatoren | AQUEOUS CONCENTRATE FOR DIALYSIS SOLUTIONS |
US4756838A (en) * | 1980-02-21 | 1988-07-12 | Veltman Preston Leonard | Preparation of dry dialysate products |
JPS56164113A (en) | 1980-05-21 | 1981-12-17 | Nikkiso Co Ltd | Preparation of dialysis solution |
JPS5756422A (en) | 1980-09-19 | 1982-04-05 | Iryo Kogaku Kenkyusho:Kk | Dialytic solution for artificial kidney |
US4489535A (en) * | 1980-10-02 | 1984-12-25 | Veltman Preston Leonard | Materials and method for preparing dialysis solutions containing bicarbonate ions |
US4339433A (en) | 1981-01-09 | 1982-07-13 | Baxter Travenol Laboratories, Inc. | Additives for peritoneal dialysis solutions |
US4761237A (en) | 1981-07-10 | 1988-08-02 | Baxter Travenol Laboratories, Inc. | Peritoneal dialysis solution containing carbohydrate polymers |
US4879280A (en) | 1981-09-24 | 1989-11-07 | Fresenius Ag | Dialysis solution for use in intraperitoneal dialysis |
EP0076355A3 (en) | 1981-10-01 | 1983-05-25 | Abbott Laboratories | Improved peritoneal dialysis solution |
US6077836A (en) * | 1983-01-12 | 2000-06-20 | Ml Laboratotries, Plc | Peritoneal dialysis and compositions for use therein |
US4886789A (en) * | 1983-01-12 | 1989-12-12 | M. L. Laboratories Plc | Peritoneal dialysis and compositions for use therein |
GB8300718D0 (en) | 1983-01-12 | 1983-02-16 | Milner Research Ireland Ltd | Glucose polymer solutions |
GB8404299D0 (en) | 1984-02-18 | 1984-03-21 | Milner Research Ireland Ltd | Peritoneal dialysis |
JPS60166378A (en) | 1984-02-09 | 1985-08-29 | Shikoku Chem Corp | Carboxymethylated glucose polymer and method for adjusting mud using said polymer |
US4604379A (en) * | 1984-06-18 | 1986-08-05 | Curators Of The University Of Missouri | Dialysis solutions containing cross-linked gelatin |
US4668400A (en) * | 1984-06-22 | 1987-05-26 | Veech Richard L | Hemodialysis processes and hemodialysis solutions |
ATE82500T1 (en) * | 1984-06-22 | 1992-12-15 | Richard L Veech | ELECTROLYTE SOLUTIONS AND THEIR (IN VIVO) USE. |
DE3428201A1 (en) | 1984-07-31 | 1986-02-06 | Laevosan-Gesellschaft mbH & Co. KG, Linz | PERITONEAL DIALYSIS SOLUTIONS |
JPS61247466A (en) * | 1985-04-25 | 1986-11-04 | テルモ株式会社 | Dialytic solution for abdominal membrane dialysis |
EP0209607B1 (en) | 1985-05-31 | 1989-12-20 | Hans Dr. Dietl | Hemodialysis liquid feed system |
US6248726B1 (en) * | 1985-06-22 | 2001-06-19 | M L Laboratories Plc | Method of peritoneal dialysis using glucose polymer solutions |
ATE106410T1 (en) | 1985-06-22 | 1994-06-15 | Ml Lab Plc | POLYMERS USED IN CONTINUOUS PERITONEAL DIALYSIS. |
GB8521712D0 (en) * | 1985-08-31 | 1985-10-02 | Giltech Ltd | Solution for peritoneal dialysis |
DE3683583D1 (en) | 1985-09-10 | 1992-03-05 | Res Corp Technologies Inc | OSMOTIC AGENTS FOR PERITONEAL DIALYSIS. |
US4976683A (en) * | 1986-06-20 | 1990-12-11 | Abbott Laboratories | Peritoneal dialysis method |
GR870129B (en) * | 1987-01-27 | 1987-02-04 | Giatzidis Ippokratis | Stable bicarbonate - glycylglycine dialysate for hemodialysis and peritoneal dialysis |
DE3812525C1 (en) * | 1988-04-15 | 1989-06-22 | Fresenius Ag, 6380 Bad Homburg, De | |
DE3821043A1 (en) | 1988-06-22 | 1989-12-28 | Fresenius Ag | DIALYZER AND SPUEL SOLUTION FOR INTRAPERITONEAL ADMINISTRATION |
JP2724597B2 (en) * | 1988-09-22 | 1998-03-09 | 日本精化株式会社 | Purification method of alkyl glycosides |
JPH02304026A (en) | 1989-05-16 | 1990-12-17 | Morishita Pharmaceut Co Ltd | Liquid for peritoneal lavage |
AU627309B2 (en) * | 1989-05-26 | 1992-08-20 | Terumo Kabushiki Kaisha | Preparation for blood dialysis and method for production thereof |
SE505967C2 (en) * | 1990-10-15 | 1997-10-27 | Gambro Ab | The respective method for preparing a medical solution, for example a dialysis solution |
JP2722131B2 (en) | 1990-10-16 | 1998-03-04 | 森永乳業株式会社 | Peritoneal dialysate |
DE69215359T2 (en) * | 1991-02-20 | 1997-04-03 | Cultor Oy | REDUCED POLYDEXTROSE |
DE4123001A1 (en) | 1991-07-11 | 1993-01-14 | Laevosan Gmbh & Co Kg | PHARMACEUTICAL COMPOSITION FOR PERITONEAL DIALYSIS |
SE9103395D0 (en) * | 1991-11-18 | 1991-11-18 | Gambro Ab | SYSTEM USING ENSTERIL MEDICAL SOLUTION CONTAINING GLUCOSE OR GLUCOSE-LIKE SUBSTANCES AND A SOLUTION INTENDED FOR THIS SYSTEM |
US5616248A (en) * | 1992-04-06 | 1997-04-01 | Schal; Wilfried | Method for the preparation of hemodialysis fluids containing bicarbonate |
DE4242926C2 (en) * | 1992-12-18 | 1994-12-15 | Fresenius Ag | Dialysis solution for peritoneal dialysis |
IT1263967B (en) * | 1993-02-24 | 1996-09-05 | SOLUTIONS FOR PERITONEAL DIALYSIS | |
US5436232A (en) * | 1994-01-07 | 1995-07-25 | Laevosan-Gesellschaft Mbh | Pharmaceutical composition for peritoneal dialysis |
US6306836B1 (en) * | 1994-01-21 | 2001-10-23 | Baxter International Inc. | Peritoneal dialysis solutions containing maltodextrins and amino acids |
JPH07252137A (en) | 1994-02-21 | 1995-10-03 | Terumo Corp | Saccharides-containing electrolyte solution |
GB9411009D0 (en) * | 1994-06-02 | 1994-07-20 | Giltech Ltd | Dialysis fluid |
JP3647898B2 (en) | 1994-06-28 | 2005-05-18 | 味の素ファルマ株式会社 | Sodium bicarbonate dialysis agent and method for producing the same |
SE510030C2 (en) * | 1995-08-08 | 1999-04-12 | Gambro Ab | Method of mixing sterile medical solution and container for carrying out the procedure |
CA2155910C (en) | 1995-08-11 | 1999-12-14 | George Wu | Biocompatible aqueous solution for use in continuous ambulatory peritoneal dialysis |
JPH0987182A (en) | 1995-09-27 | 1997-03-31 | Terumo Corp | Neutral peritoneal dialysis fluid |
SE9600631D0 (en) * | 1996-02-20 | 1996-02-20 | Gambro Ab | Use of a solution containing glucose for peritonial dialysis having reduced formation of AGE products |
JPH1094598A (en) * | 1996-07-31 | 1998-04-14 | Baxter Internatl Inc | Peritoneal dialysis liquid |
DE19631124A1 (en) * | 1996-08-01 | 1998-02-05 | Fresenius Medical Care De Gmbh | Process for the preparation of an infusion or dialysis solution containing bicarbonate |
GB9714218D0 (en) | 1997-07-04 | 1997-09-10 | Allied Therapeutics Ltd | Peritoneal dialysis fluid |
SE9703775L (en) | 1997-10-16 | 1999-04-17 | Pharmalink Baslaekemedel Ab | Preparation of glucose-containing sterial solutions |
DE69929550T8 (en) * | 1998-05-21 | 2006-12-28 | Nipro Corp. | Albumin-containing solution for peritoneal dialysis |
EP0980685B1 (en) * | 1998-06-17 | 2006-01-25 | Nipro Corporation | Use of a fluid for the manufacture of a dialysis fluid for continuous recirculating peritoneal dialysis |
JP2000037452A (en) | 1998-07-21 | 2000-02-08 | Terumo Corp | Peritoneum dialysis fluid |
SE521219C2 (en) * | 1998-10-23 | 2003-10-14 | Gambro Ab | Method and apparatus for reducing the degradation of heat sensitive components in medical substances during heat sterilization |
JP4284737B2 (en) | 1999-02-26 | 2009-06-24 | 株式会社ジェイ・エム・エス | Neutral peritoneal dialysis solution |
US6251437B1 (en) * | 1999-07-13 | 2001-06-26 | Minntech Corporation | Liquid/powder acid concentrate for dialysate and a method of making the same |
ES2270620T3 (en) | 1999-10-11 | 2007-04-01 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | USE OF L-CARNITINE AND ITS ALCANOYL DERIVATIVES AS OSMOTIC AGENTS IN SOLUTIONS FOR MEDICAL USE. |
US20030202958A1 (en) * | 1999-10-15 | 2003-10-30 | Strickland Alan D. | Dialysis solution including polyglycol osmotic agent |
EP1343489A2 (en) * | 2000-12-20 | 2003-09-17 | Dialysis Solutions Inc. | Sterile bicarbonate-free dialysis concentrate solutions |
US6787039B2 (en) * | 2001-01-26 | 2004-09-07 | Degussa Ag | Amino acid composition for hemodialysis |
JP2002308782A (en) | 2001-02-06 | 2002-10-23 | Otsuka Pharmaceut Factory Inc | Method for producing bicarbonate solution |
JP2002282354A (en) | 2001-03-27 | 2002-10-02 | Jms Co Ltd | Liquid for peritoneal dialysis |
GB0108359D0 (en) | 2001-04-03 | 2001-05-23 | Allied Therapeutics Ltd | Peritoneal dialysis fluid |
US6821547B2 (en) * | 2001-04-10 | 2004-11-23 | Danisco Usa, Inc. | Polymerization of mono and disaccharides with monocarboxylic acids and lactones |
WO2003013553A1 (en) | 2001-08-10 | 2003-02-20 | Van Dyck Diaz Rodolfo Candelar | Dialysis solution formula and gastrointestinal dialysis method |
DE10217356B4 (en) | 2002-04-18 | 2012-03-29 | Fresenius Medical Care Deutschland Gmbh | Solution for peritoneal dialysis |
-
1998
- 1998-12-04 US US09/206,063 patent/US6770148B1/en not_active Expired - Fee Related
-
1999
- 1999-11-18 ID IDW20001692A patent/ID27897A/en unknown
- 1999-11-18 CA CA002319561A patent/CA2319561A1/en not_active Abandoned
- 1999-11-18 AU AU17384/00A patent/AU762933B2/en not_active Ceased
- 1999-11-18 DE DE69935498T patent/DE69935498T2/en not_active Expired - Lifetime
- 1999-11-18 JP JP2000586342A patent/JP4338317B2/en not_active Expired - Fee Related
- 1999-11-18 ES ES99960509T patent/ES2284281T3/en not_active Expired - Lifetime
- 1999-11-18 DK DK99960509T patent/DK1051183T3/en active
- 1999-11-18 WO PCT/US1999/027456 patent/WO2000033851A1/en active IP Right Grant
- 1999-11-18 CN CNB998026840A patent/CN1150903C/en not_active Expired - Fee Related
- 1999-11-18 AT AT99960509T patent/ATE356627T1/en not_active IP Right Cessation
- 1999-11-18 MX MXPA00008653A patent/MXPA00008653A/en not_active IP Right Cessation
- 1999-11-18 EP EP99960509A patent/EP1051183B1/en not_active Expired - Lifetime
- 1999-11-18 KR KR1020007008455A patent/KR100597931B1/en not_active IP Right Cessation
- 1999-11-18 BR BR9909095-3A patent/BR9909095A/en active Search and Examination
- 1999-11-30 TW TW088120899A patent/TW555561B/en not_active IP Right Cessation
- 1999-12-01 AR ARP990106117A patent/AR021515A1/en not_active Application Discontinuation
- 1999-12-03 CO CO99076224A patent/CO5150157A1/en unknown
-
2001
- 2001-06-15 US US09/882,187 patent/US20010044424A1/en not_active Abandoned
- 2001-09-26 HK HK01106795A patent/HK1036014A1/en not_active IP Right Cessation
-
2004
- 2004-04-14 US US10/824,549 patent/US7208479B2/en not_active Expired - Fee Related
-
2008
- 2008-10-03 JP JP2008259107A patent/JP2009019060A/en not_active Withdrawn
-
2009
- 2009-09-24 JP JP2009219817A patent/JP5286208B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
TW555561B (en) | 2003-10-01 |
EP1051183A1 (en) | 2000-11-15 |
ATE356627T1 (en) | 2007-04-15 |
US20010044424A1 (en) | 2001-11-22 |
KR100597931B1 (en) | 2006-07-13 |
CA2319561A1 (en) | 2000-06-15 |
JP2010001309A (en) | 2010-01-07 |
CN1290170A (en) | 2001-04-04 |
ID27897A (en) | 2001-05-03 |
AU1738400A (en) | 2000-06-26 |
JP5286208B2 (en) | 2013-09-11 |
US6770148B1 (en) | 2004-08-03 |
AU762933B2 (en) | 2003-07-10 |
US20040192648A1 (en) | 2004-09-30 |
CN1150903C (en) | 2004-05-26 |
DK1051183T3 (en) | 2007-05-07 |
EP1051183B1 (en) | 2007-03-14 |
DE69935498D1 (en) | 2007-04-26 |
WO2000033851A1 (en) | 2000-06-15 |
DE69935498T2 (en) | 2007-11-29 |
JP4338317B2 (en) | 2009-10-07 |
KR20010040586A (en) | 2001-05-15 |
HK1036014A1 (en) | 2001-12-21 |
ES2284281T3 (en) | 2007-11-01 |
CO5150157A1 (en) | 2002-04-29 |
AR021515A1 (en) | 2002-07-24 |
MXPA00008653A (en) | 2005-12-01 |
JP2009019060A (en) | 2009-01-29 |
US7208479B2 (en) | 2007-04-24 |
JP2002531226A (en) | 2002-09-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9909095A (en) | Peritoneal dialysis solution containing modified icodextrins | |
JP3334055B2 (en) | Fast acting chemical sterilant | |
AT398079B (en) | PREPARATION WITH THROMBINE ACTIVITY AND METHOD FOR THEIR PRODUCTION | |
BR8602549A (en) | STERILIZING COMPOSITION AND SOLUTION | |
AU2728900A (en) | Multi-purpose acid compositions | |
CA2034489A1 (en) | Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions | |
BR0013677A (en) | Metal-containing compositions, preparations and uses | |
FR2679251B1 (en) | PROCESS FOR THE PREPARATION OF A HUMAN THROMBIN CONCENTRATE FOR THERAPEUTIC USE. | |
BRPI9914741A (en) | n-(2-aryl-proprionyl)-sulfonamides, uses and pharmaceutical compositions containing them. | |
NZ210275A (en) | Modified hirudin and its antithrombin properties | |
ES509941A0 (en) | "A PROCEDURE FOR THERMAL TREATMENT WITH THE PURPOSES OF INACTIVATION OF THE HEPATITIS VIRUS IN A COMPOSITION OF FACTOR VIII OF COAGULATION OF HUMAN BLOOD". | |
CA2179017A1 (en) | Peracetic acid sterilization | |
BR0207502A (en) | Compounds, enantiomers, pharmaceutical composition, use of compounds, and process for manufacturing compounds | |
BR9808911A (en) | Improved storage and maintenance of blood products | |
WO2003077835A3 (en) | Sodium dodecyl sulfate compositions for inactivating prions | |
DK1040833T3 (en) | Bone resorption suppressant | |
BR0106707A (en) | Method for sterilizing fungi and / or bacteria in a spore state, and sterilizing against fungi and / or bacteria in a spore state | |
HRP931496A2 (en) | Process for the preparation of biological preparations not containing (active) viruses | |
BR0011430A (en) | Improved storage and maintenance of blood products including red blood cells and platelets | |
GR3025488T3 (en) | Transformed erythrocytes, process for preparing the same, and their use in pharmaceutical compositions | |
BR0011055A (en) | Sterilization method | |
TW337997B (en) | Pharmaceutical preparation containing plasminogen activators | |
KR930009612A (en) | Method for preparing virus-free thrombin concentrate | |
ES2072975T3 (en) | MIXTURE OF STERILIZER AND STERILIZATION METHOD. | |
WO2003055559A8 (en) | Dialkyl-substituted acetic acid and glyceric acid based active substance combinations against bacteria, mycota and viruses |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DE INT.CL: A61K 31/716, A61K 31/718, A61K 9/08, A61M 1/28, A61P 7/08 Ipc: A61K 31/716 (2008.04), A61K 31/718 (2008.04), A61K |
|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B11D | Dismissal acc. art. 38, par 2 of ipl - failure to pay fee after grant in time |