BR9908213A - Genes of riboflavin biosynthesis from plants and their uses - Google Patents

Genes of riboflavin biosynthesis from plants and their uses

Info

Publication number
BR9908213A
BR9908213A BR9908213-6A BR9908213A BR9908213A BR 9908213 A BR9908213 A BR 9908213A BR 9908213 A BR9908213 A BR 9908213A BR 9908213 A BR9908213 A BR 9908213A
Authority
BR
Brazil
Prior art keywords
genes
plants
riboflavin
plant
biosynthesis
Prior art date
Application number
BR9908213-6A
Other languages
Portuguese (pt)
Inventor
Charles David Guyer
Marie Ann Johnson
Sandra Lynn Volrath
Sandra Alice Brunn
Eric Russell Ward
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR9908213A publication Critical patent/BR9908213A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Patente de Invenção: <B>GENES DA BIOSSìNTESE DE RIBOFLAVINA A PARTIR DE PLANTAS E USOS DOS MESMOS''<D>. A presente invenção fornece genes da biossíntese de riboflavina de planta, incluindo um gene que codifica a subunidade ß do complexo de enzimas de sintase de riboflavina (sintase de lumazina) e um gene que codifica a enzima bifuncional ciclohidrolasell de GTP/ sintase de DHBP. Também divulgados são a preparação recombinante dessas enzimas da biossíntese de riboflavina em hospedeiros heterólogos, produtos químicos de triagem para atividade herbicida usando essas enzimas preparadas recombinantemente e o uso dos produtos químicos herbicidas assim identificados para suprimir o crescimento de vegetação indesejada. Além disso, a presente invenção fornece processos para o desenvolvimento de tolerância herbicida em plantas, tecidos de plantas, sementes de plantas e células de plantas usando-se os genes da biossíntese de riboflavina da invenção.Invention Patent: <B> GENES OF RIBOFLAVINE BIOSYNTHESIS FROM PLANTS AND USES OF THE SAME '' <D>. The present invention provides plant riboflavin biosynthesis genes, including a gene encoding the ß subunit of the riboflavin synthase enzyme complex (lumazine synthase) and a gene encoding the bifunctional enzyme cyclohydrolasell GTP / DHBP synthase. Also disclosed are the recombinant preparation of these enzymes from riboflavin biosynthesis in heterologous hosts, screening chemicals for herbicidal activity using these recombinantly prepared enzymes and the use of the herbicidal chemicals thus identified to suppress the growth of unwanted vegetation. In addition, the present invention provides processes for the development of herbicidal tolerance in plants, plant tissues, plant seeds and plant cells using the riboflavin biosynthesis genes of the invention.

BR9908213-6A 1998-01-30 1999-01-28 Genes of riboflavin biosynthesis from plants and their uses BR9908213A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10981098P 1998-01-30 1998-01-30
PCT/EP1999/000556 WO1999038986A2 (en) 1998-01-30 1999-01-28 Riboflavin biosynthesis genes from plants and uses thereof

Publications (1)

Publication Number Publication Date
BR9908213A true BR9908213A (en) 2000-11-28

Family

ID=22329685

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9908213-6A BR9908213A (en) 1998-01-30 1999-01-28 Genes of riboflavin biosynthesis from plants and their uses

Country Status (17)

Country Link
EP (1) EP1051504A2 (en)
JP (1) JP2002501753A (en)
KR (1) KR20010082509A (en)
CN (1) CN1289369A (en)
AU (1) AU744487B2 (en)
BR (1) BR9908213A (en)
CA (1) CA2318522A1 (en)
CZ (1) CZ20002750A3 (en)
HU (1) HUP0101278A3 (en)
ID (1) ID25910A (en)
IL (1) IL137303A0 (en)
IN (1) IN2000CH00209A (en)
MX (1) MXPA00007432A (en)
PL (1) PL342805A1 (en)
TR (1) TR200002193T2 (en)
WO (1) WO1999038986A2 (en)
ZA (1) ZA99716B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002522089A (en) * 1998-08-12 2002-07-23 マキシジェン， インコーポレイテッド DNA shuffling to produce herbicide-selective crops
AU1979500A (en) * 1998-12-15 2000-07-24 Adelbert Bacher Method for screening for inhibitors of riboflavin biosynthesis
DE19910102B4 (en) * 1999-03-08 2006-06-01 Fischer, Markus, Dr.rer.nat. Protein conjugates, methods, vectors, proteins and DNA for their production, their use, and medicines and vaccines containing the same
DE19942175A1 (en) * 1999-09-03 2001-03-08 Adelbert Bacher Method for finding inhibitors of riboflavin biosynthesis
AU2001248371A1 (en) * 2000-04-18 2001-10-30 Syngenta Participations Ag Amino acid:glyoxylate aminotransferase genes from plants and uses thereof
CN110964769B (en) * 2019-11-29 2022-11-11 河南巨龙生物工程股份有限公司 Method for improving yield of riboflavin produced by fermenting bacillus subtilis

Also Published As

Publication number Publication date
AU744487B2 (en) 2002-02-28
CZ20002750A3 (en) 2000-11-15
AU2720299A (en) 1999-08-16
MXPA00007432A (en) 2001-02-01
CN1289369A (en) 2001-03-28
IN2000CH00209A (en) 2005-05-20
CA2318522A1 (en) 1999-08-05
EP1051504A2 (en) 2000-11-15
HUP0101278A2 (en) 2001-08-28
PL342805A1 (en) 2001-07-02
WO1999038986A3 (en) 1999-09-23
KR20010082509A (en) 2001-08-30
HUP0101278A3 (en) 2003-04-28
TR200002193T2 (en) 2001-05-21
JP2002501753A (en) 2002-01-22
IL137303A0 (en) 2001-07-24
WO1999038986A2 (en) 1999-08-05
ID25910A (en) 2000-11-09
ZA99716B (en) 1999-07-30

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