BR9907169A - "derivados de cabeça de ponte de piridila e seus análogos, composições farmacêuticas e seus empregos como inibidores de receptores colinérgicos nicotìnicos" - Google Patents

"derivados de cabeça de ponte de piridila e seus análogos, composições farmacêuticas e seus empregos como inibidores de receptores colinérgicos nicotìnicos"

Info

Publication number
BR9907169A
BR9907169A BR9907169-0A BR9907169A BR9907169A BR 9907169 A BR9907169 A BR 9907169A BR 9907169 A BR9907169 A BR 9907169A BR 9907169 A BR9907169 A BR 9907169A
Authority
BR
Brazil
Prior art keywords
pharmaceutical compositions
derivatives
nicotinic cholinergic
inhibitors
bridgehead
Prior art date
Application number
BR9907169-0A
Other languages
English (en)
Portuguese (pt)
Inventor
Jeffrey Daniel Schmitt
Peter Anthony Crooks
Gary Maurice Dull
Original Assignee
Reynolds Tobacco Co R
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reynolds Tobacco Co R filed Critical Reynolds Tobacco Co R
Publication of BR9907169A publication Critical patent/BR9907169A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR9907169-0A 1998-12-11 1999-08-31 "derivados de cabeça de ponte de piridila e seus análogos, composições farmacêuticas e seus empregos como inibidores de receptores colinérgicos nicotìnicos" BR9907169A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/210,113 US6432975B1 (en) 1998-12-11 1998-12-11 Pharmaceutical compositions and methods for use
PCT/US1999/019906 WO2000034276A1 (en) 1998-12-11 1999-08-31 Pyridyl-bridgehead derivatives and their analogues, pharmaceutical compositions and their use as inhibitors of nicotinic cholinergic receptors

Publications (1)

Publication Number Publication Date
BR9907169A true BR9907169A (pt) 2000-10-17

Family

ID=22781623

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907169-0A BR9907169A (pt) 1998-12-11 1999-08-31 "derivados de cabeça de ponte de piridila e seus análogos, composições farmacêuticas e seus empregos como inibidores de receptores colinérgicos nicotìnicos"

Country Status (7)

Country Link
US (2) US6432975B1 (https=)
EP (1) EP1053236A1 (https=)
JP (1) JP2002531564A (https=)
AU (1) AU5699399A (https=)
BR (1) BR9907169A (https=)
CA (1) CA2317025A1 (https=)
WO (1) WO2000034276A1 (https=)

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DE60306896T2 (de) 2002-02-21 2007-02-15 Aprea Ab Verwendung von niedermolekularen verbindungen zur herstellung eines medikaments zur behandlung von durch mutation p53-vermittelten erkrankungen
GB0220581D0 (en) 2002-09-04 2002-10-09 Novartis Ag Organic Compound
WO2004039815A2 (en) * 2002-11-01 2004-05-13 Pharmacia & Upjohn Company Llc Compounds having both alpha7 nachr agonist and 5ht antagonist activity for treatment of cns diseases
JP4750421B2 (ja) * 2002-12-06 2011-08-17 ノース ショア−ロング アイランド ジュ−イッシュ リサ−チ インスティチュ−ト α７受容体結合コリン作動性アゴニストを用いる炎症の阻害
US7238715B2 (en) * 2002-12-06 2007-07-03 The Feinstein Institute For Medical Research Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
SE0400708D0 (sv) * 2004-03-22 2004-03-22 Aprea Ab New compounds and use thereof
AR049401A1 (es) 2004-06-18 2006-07-26 Novartis Ag Aza-biciclononanos
GB0415746D0 (en) 2004-07-14 2004-08-18 Novartis Ag Organic compounds
GB0521508D0 (en) 2005-10-21 2005-11-30 Novartis Ag Organic compounds
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GB0525672D0 (en) 2005-12-16 2006-01-25 Novartis Ag Organic compounds
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SA08290475B1 (ar) 2007-08-02 2013-06-22 Targacept Inc (2s، 3r)-n-(2-((3-بيردينيل)ميثيل)-1-آزا بيسيكلو[2، 2، 2]أوكت-3-يل)بنزو فيوران-2-كربوكساميد، وصور أملاحه الجديدة وطرق استخدامه
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TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
JO3250B1 (ar) 2009-09-22 2018-09-16 Novartis Ag إستعمال منشطات مستقبل نيكوتينيك أسيتيل كولين ألفا 7
PE20170923A1 (es) 2010-05-17 2017-07-12 Forum Pharmaceuticals Inc Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidratado
EP3461481A1 (en) 2012-05-08 2019-04-03 Forum Pharmaceuticals Inc. Methods of maintaining, treating or improving cognitive function
MX2014014323A (es) 2012-05-25 2015-02-12 Janssen R & D Ireland Nucleosidos de espirooxetano de uracilo.
BR112015014457A2 (pt) 2012-12-21 2017-11-21 Alios Biopharma Inc composto ou sal farmaceuticamente aceitável do mesmo e composição farmacêutica e respectivos usos e processos para melhorar ou tratar infecção de hcv, para inibir a atividade da ns5b polimerase do vírus da hepatite c e a replicação de vírus da hepatite c
AU2015311805B2 (en) * 2014-09-05 2020-04-02 Celgene Quanticel Research, Inc. Inhibitors of lysine specific demethylase-1
US9724340B2 (en) 2015-07-31 2017-08-08 Attenua, Inc. Antitussive compositions and methods
TWI775313B (zh) 2020-02-18 2022-08-21 美商基利科學股份有限公司 抗病毒化合物
KR20250133471A (ko) 2020-02-18 2025-09-05 길리애드 사이언시즈, 인코포레이티드 항바이러스 화합물
TWI883391B (zh) 2020-02-18 2025-05-11 美商基利科學股份有限公司 抗病毒化合物
CA3216162A1 (en) 2021-04-16 2022-10-20 Gilead Sciences, Inc. Methods of preparing carbanucleosides using amides
AU2022328698B2 (en) 2021-08-18 2025-02-20 Gilead Sciences, Inc. Phospholipid compounds and methods of making and using the same

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Also Published As

Publication number Publication date
JP2002531564A (ja) 2002-09-24
EP1053236A1 (en) 2000-11-22
US6432975B1 (en) 2002-08-13
AU5699399A (en) 2000-06-26
US20030045523A1 (en) 2003-03-06
WO2000034276A1 (en) 2000-06-15
CA2317025A1 (en) 2000-06-15

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Legal Events

Date Code Title Description
PC Transfer

Free format text: TARGACEPT, INC. (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE ACORDO COM O ART. 37, POR CONTRARIAR O DISPOSTO NOS ART. 8O, 13 E 25DA LPI.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.