BR9906950A - Processo para a preparação de isoflavonas - Google Patents

Processo para a preparação de isoflavonas

Info

Publication number
BR9906950A
BR9906950A BR9906950-4A BR9906950A BR9906950A BR 9906950 A BR9906950 A BR 9906950A BR 9906950 A BR9906950 A BR 9906950A BR 9906950 A BR9906950 A BR 9906950A
Authority
BR
Brazil
Prior art keywords
isoflavones
preparing
preparing isoflavones
hydroxydeoxybenzoin
chloromethylene
Prior art date
Application number
BR9906950-4A
Other languages
English (en)
Other versions
BR9906950B1 (pt
Inventor
Balasubramanian Sreenivasan
Muraleedharan G Nair
Original Assignee
Univ Michigan State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Michigan State filed Critical Univ Michigan State
Publication of BR9906950A publication Critical patent/BR9906950A/pt
Publication of BR9906950B1 publication Critical patent/BR9906950B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCESSO PARA A PREPARAçãO DE ISOFLAVONAS Um processo para a preparação de uma isoflavona de 2'-hidroxideoxibenzoina (I) é descrito. O processo usa N,N'-cloreto de dimetil (clorometileno) amónio preparado como um reagente com (I) em trifluoreto de boro eterato ou outro ácido Lewis como solvente. As isoflavonas são conhecidos compostos biologicamente ativos.
BRPI9906950-4A 1998-09-16 1999-06-09 processo para a preparação de isoflavonas, e processo para a preparação de formononetina. BR9906950B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/154,230 US5981775A (en) 1998-09-16 1998-09-16 Process for the preparation of isoflavones
US09/154.230 1998-09-16
PCT/US1999/013045 WO2000015627A1 (en) 1998-09-16 1999-06-09 Process for the preparation of isoflavones

Publications (2)

Publication Number Publication Date
BR9906950A true BR9906950A (pt) 2000-10-17
BR9906950B1 BR9906950B1 (pt) 2009-12-01

Family

ID=22550537

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9906950-4A BR9906950B1 (pt) 1998-09-16 1999-06-09 processo para a preparação de isoflavonas, e processo para a preparação de formononetina.

Country Status (8)

Country Link
US (1) US5981775A (pt)
EP (1) EP1032568B1 (pt)
KR (1) KR100355184B1 (pt)
AT (1) ATE287879T1 (pt)
BR (1) BR9906950B1 (pt)
CA (1) CA2306836C (pt)
DE (1) DE69923426T2 (pt)
WO (1) WO2000015627A1 (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100378105C (zh) * 2003-01-31 2008-04-02 中国人民解放军南京军区联勤部军事医学研究所 吡喃异黄酮类化合物的合成方法
KR100580953B1 (ko) * 2003-04-30 2006-05-16 충남대학교산학협력단 인터루킨-5 억제효과를 갖는 신규 아이소플라본논계 유도체
WO2005054169A1 (en) * 2003-12-08 2005-06-16 Hanbul Cosmetic Co., Ltd. Preparation method of 2-phenylacetophenone derivatives
KR100542724B1 (ko) * 2004-01-20 2006-01-11 한불화장품주식회사 이소플라보노이드 계열 화합물의 제조방법
US9049814B2 (en) * 2007-02-23 2015-06-09 Vamtech, Llc Coated seeds and methods of making coated seeds
EP1961727A1 (de) * 2007-02-26 2008-08-27 Bayer CropScience AG Verfahren zur Herstellung von 2,4-Dihydroxyphenyl-4-methoxybenzyl-ketonen
US7863325B2 (en) 2008-12-11 2011-01-04 Axcentua Pharmaceuticals Ab Crystalline genistein sodium salt dihydrate
CA2746652C (en) 2008-12-11 2018-03-06 Axcentua Pharmaceuticals Ab Crystalline forms of genistein
CN102002030B (zh) * 2010-11-30 2012-10-24 天津市佰斯康科技有限公司 刺芒柄花素的合成方法
CN106278843A (zh) * 2016-08-17 2017-01-04 山西同济药业有限公司 2,4‑二羟基‑4‑甲氧基脱氧安息香的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU162377B (pt) * 1970-05-27 1973-02-28
GB1495189A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 4-oxo-4h-benzopyran derivatives and process for their preparation
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi
US5149866A (en) * 1991-08-14 1992-09-22 Hoechst Celanese Corporation Process for the preparation of omega-arylalkanoic acids
FR2693724B1 (fr) * 1992-07-17 1994-10-07 Lipha Utilisation de composés benzopyraniques ou benzothiopyraniques pour l'induction de l'expression des gènes de la nodulation des bactéries du genre Rhizobium associées aux légumineuses.
US5691275A (en) * 1996-01-29 1997-11-25 Board Of Trustees Operating Michigan State University Alkali metal formononetin and method of mycorrhizal stimulation

Also Published As

Publication number Publication date
KR20010031436A (ko) 2001-04-16
KR100355184B1 (ko) 2002-10-11
US5981775A (en) 1999-11-09
CA2306836C (en) 2003-10-28
WO2000015627A1 (en) 2000-03-23
BR9906950B1 (pt) 2009-12-01
EP1032568A4 (en) 2003-03-05
EP1032568A1 (en) 2000-09-06
CA2306836A1 (en) 2000-03-23
EP1032568B1 (en) 2005-01-26
ATE287879T1 (de) 2005-02-15
DE69923426D1 (de) 2005-03-03
DE69923426T2 (de) 2005-06-30

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 12/01/2010, OBSERVADAS AS CONDICOES LEGAIS.

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 12.01.2020