BR9814353A - Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga - Google Patents
Colìrio hidrosolúvel com tempo longo de duração da eficácia da drogaInfo
- Publication number
- BR9814353A BR9814353A BR9814353-0A BR9814353A BR9814353A BR 9814353 A BR9814353 A BR 9814353A BR 9814353 A BR9814353 A BR 9814353A BR 9814353 A BR9814353 A BR 9814353A
- Authority
- BR
- Brazil
- Prior art keywords
- water
- soluble
- long
- eye drops
- drug effectiveness
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4704—2-Quinolinones, e.g. carbostyril
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
<B>COLìRIO HIDROSOLúVEL COM TEMPO LONGO DE DURAçãO DA EFICáCIA DA DROGA<D> A descoberta é um colírio hidrosolúvel compreendendo (a) pelo menos um selecionando do carteolol e um sal ácido de adição ácida deste, (b) pelo menos um polímero acrílico selecionado de um ácido poliacrílico do tipo cadeia reta e um sal hidrosolúvel farmaceuticamente aceitável deste, e (c) pelo menos um selecionado de um sal metálico alcalino hidrosolúvel e uma amina hidrosolúvel. O colírio hidrosolúvel da presente invenção tem um tempo de duração da eficácia da droga consideravelmente longo, e é superior na ação inibitória sobre a pressão intra-ocular e é efetivo para o tratamento do glaucoma.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP35303997 | 1997-12-22 | ||
JP29855098 | 1998-10-20 | ||
PCT/JP1998/005699 WO1999032087A1 (en) | 1997-12-22 | 1998-12-16 | Water-soluble eye drop |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9814353A true BR9814353A (pt) | 2000-10-03 |
Family
ID=26561565
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9814353-0A BR9814353A (pt) | 1997-12-22 | 1998-12-16 | Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga |
Country Status (19)
Country | Link |
---|---|
US (1) | US6303631B1 (pt) |
EP (1) | EP1054662B1 (pt) |
JP (1) | JP2000191534A (pt) |
KR (1) | KR100350824B1 (pt) |
CN (1) | CN1137679C (pt) |
AR (1) | AR017939A1 (pt) |
AT (1) | ATE266386T1 (pt) |
AU (1) | AU740756B2 (pt) |
BR (1) | BR9814353A (pt) |
CA (1) | CA2315818C (pt) |
DE (1) | DE69823879T2 (pt) |
DK (1) | DK1054662T3 (pt) |
ES (1) | ES2218873T3 (pt) |
HK (1) | HK1033437A1 (pt) |
ID (1) | ID25544A (pt) |
MY (1) | MY116782A (pt) |
PT (1) | PT1054662E (pt) |
TW (1) | TW520296B (pt) |
WO (1) | WO1999032087A1 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6423526B1 (en) * | 1999-11-23 | 2002-07-23 | Zymogenetics, Inc. | Human serine protease |
CA2402405C (en) * | 2000-07-14 | 2008-02-12 | Allergan Sales, Inc. | Compositions containing alpha-2-adrenergic agonist components |
JP2002154989A (ja) * | 2000-11-14 | 2002-05-28 | Lion Corp | 眼科用組成物、及び生体粘膜への薬物の滞留性向上組成物 |
AU2002256471B2 (en) * | 2001-05-03 | 2007-05-24 | Allergan, Inc. | Compositions having enhanced pharmacokinetic characteristics |
JP3974117B2 (ja) | 2004-03-23 | 2007-09-12 | 理想科学工業株式会社 | 孔版印刷用インキ |
JP5403850B2 (ja) * | 2004-06-08 | 2014-01-29 | ロート製薬株式会社 | 眼科用清涼組成物 |
US7758553B2 (en) * | 2006-04-03 | 2010-07-20 | Insight Vision Incorporated | Drop dispenser for the delivery of uniform droplets of viscous liquids |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6056684B2 (ja) | 1977-11-07 | 1985-12-11 | 東興薬品工業株式会社 | 点眼剤 |
AU518814B2 (en) | 1979-01-30 | 1981-10-22 | Otsuka Pharamaceutical Co. | Glaucoma treatment |
US5461081A (en) | 1989-09-28 | 1995-10-24 | Alcon Laboratories, Inc. | Topical ophthalmic pharmaceutical vehicles |
SE512871C2 (sv) * | 1992-08-20 | 2000-05-29 | Santen Oy | Oftalmologisk beredning innehållande pilokarpin och ytterligare medel för behandling av okular hypertension |
SE9401109D0 (sv) * | 1994-03-31 | 1994-03-31 | Leiras Oy | Opthalmic composition II |
-
1998
- 1998-12-14 MY MYPI98005628A patent/MY116782A/en unknown
- 1998-12-16 AT AT98961377T patent/ATE266386T1/de not_active IP Right Cessation
- 1998-12-16 US US09/582,030 patent/US6303631B1/en not_active Expired - Fee Related
- 1998-12-16 PT PT98961377T patent/PT1054662E/pt unknown
- 1998-12-16 AU AU16827/99A patent/AU740756B2/en not_active Ceased
- 1998-12-16 KR KR1020007006926A patent/KR100350824B1/ko not_active IP Right Cessation
- 1998-12-16 CN CNB988125749A patent/CN1137679C/zh not_active Expired - Fee Related
- 1998-12-16 ES ES98961377T patent/ES2218873T3/es not_active Expired - Lifetime
- 1998-12-16 DE DE69823879T patent/DE69823879T2/de not_active Expired - Fee Related
- 1998-12-16 BR BR9814353-0A patent/BR9814353A/pt not_active Application Discontinuation
- 1998-12-16 DK DK98961377T patent/DK1054662T3/da active
- 1998-12-16 WO PCT/JP1998/005699 patent/WO1999032087A1/en active IP Right Grant
- 1998-12-16 CA CA002315818A patent/CA2315818C/en not_active Expired - Fee Related
- 1998-12-16 EP EP98961377A patent/EP1054662B1/en not_active Expired - Lifetime
- 1998-12-16 ID IDW20001215A patent/ID25544A/id unknown
- 1998-12-21 TW TW087121306A patent/TW520296B/zh not_active IP Right Cessation
- 1998-12-21 AR ARP980106575A patent/AR017939A1/es not_active Application Discontinuation
- 1998-12-22 JP JP10364461A patent/JP2000191534A/ja active Pending
-
2001
- 2001-06-18 HK HK01104164A patent/HK1033437A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU740756B2 (en) | 2001-11-15 |
ATE266386T1 (de) | 2004-05-15 |
CA2315818A1 (en) | 1999-07-01 |
DE69823879D1 (de) | 2004-06-17 |
KR20010024797A (ko) | 2001-03-26 |
TW520296B (en) | 2003-02-11 |
ID25544A (id) | 2000-10-12 |
DK1054662T3 (da) | 2004-07-19 |
KR100350824B1 (ko) | 2002-08-29 |
AU1682799A (en) | 1999-07-12 |
AR017939A1 (es) | 2001-10-24 |
PT1054662E (pt) | 2004-07-30 |
CA2315818C (en) | 2005-10-11 |
ES2218873T3 (es) | 2004-11-16 |
EP1054662B1 (en) | 2004-05-12 |
DE69823879T2 (de) | 2005-03-24 |
HK1033437A1 (en) | 2001-08-31 |
EP1054662A1 (en) | 2000-11-29 |
CN1137679C (zh) | 2004-02-11 |
MY116782A (en) | 2004-03-31 |
US6303631B1 (en) | 2001-10-16 |
JP2000191534A (ja) | 2000-07-11 |
WO1999032087A1 (en) | 1999-07-01 |
CN1283105A (zh) | 2001-02-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9908779A (pt) | Composições para revestimento de lente intraocular | |
BR0011448A (pt) | Imidazoquinolinas substituìdas por amida | |
ATE185792T1 (de) | Stilbenderivate und diese enthaltende pharmazeutische zusammensetzungen | |
PT1341533E (pt) | Combinacoes sinergisticas compreendendo um inibidor de renina para doencas cardiovasculares | |
BG106586A (en) | Pyrazolopyramidines as therapeutic agents | |
GT200100137A (es) | Pro-drogas de derivados de 4-fenil-piridina. | |
BR9916772A (pt) | Quinolinacarboxamidas como agentes antivirais | |
ES2196625T3 (es) | Polidialilamina no sustituida para tratar la hipercolesterolemia. | |
NZ503980A (en) | 4(3)substituted-4(3)-aminomethyl-(thio)pyran or -piperidine derivatives (= gabapentin analogues), pharmaceuticals thereof, and their use in the treatment of neurological disorders | |
ES2101191T3 (es) | Cartucho de tinta. | |
CA2380205A1 (en) | Novel bicyclonucleoside analogues | |
BR9814353A (pt) | Colìrio hidrosolúvel com tempo longo de duração da eficácia da droga | |
BRPI0414017A8 (pt) | pró-fármacos poliméricos de múltiplos braços | |
BG101960A (en) | Controlled release of myotic and mydriatic medicaments in the front occular chamber | |
BR9909256A (pt) | 2- trans- (4-aminociclohexil)amino]purinas 6,9-di-substituìdas | |
CY1107729T1 (el) | Φαρμακευτικες συνθεσεις | |
EA199900811A1 (ru) | Композиция для офтальмологических хирургических операций (варианты) и способ их осуществления | |
AR035637A1 (es) | Betamimeticos de larga accion, procedimiento para su preparacion y su empleo como medicamentos | |
TR199901259T2 (xx) | Nos inhibit�rleri olarak fayda ta��yan 6-fenilpiridil-2-amin t�revleri | |
TR199901191T2 (xx) | Benzamidoaldehitlerin sistein proteaz� inhibit�r� olarak kullan�m�. | |
ES2421948T3 (es) | Compuestos y composiciones para suministrar agentes activos | |
WO2003006893A3 (en) | Methods of inhibiting amyloid toxicity | |
BR0113389A (pt) | Compostos que inibem a atividade do fator xa | |
BR0011700A (pt) | Dinitrilas de ácido arilmalÈnico substituìdo como intermediários para a preparação de herbicidas | |
BR0012291A (pt) | Fenoxifluorpirimidinas |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DE INT.CL.8: A61K 47/32, A61K 31/4704, A61K 9/08, A61K 47/02, A61K 47/18, A61P 27/06 Ipc: A61K 47/32 (2007.10), A61K 31/4704 (2007.10), A61K |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE ESTE NAO POSSUI ATIVIDADE INVENTIVA, CONTRARIANDO O DISPOSTO NOS ARTIGOS 8O E 13 DA LPI |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] |