BR9813408A - Composição, composição farmacêutica, processo de induzir uma resposta imune contra pvs25 na superfìcie de oocinetos de plasmodium vivax, composição imunogênica capaz de eliciar uma resposta imunogênica, ácido nucleico, vetor célula, e, processo de indução de uma resposta imune bloqueadora da transmissão em um mamìfero - Google Patents

Composição, composição farmacêutica, processo de induzir uma resposta imune contra pvs25 na superfìcie de oocinetos de plasmodium vivax, composição imunogênica capaz de eliciar uma resposta imunogênica, ácido nucleico, vetor célula, e, processo de indução de uma resposta imune bloqueadora da transmissão em um mamìfero

Info

Publication number
BR9813408A
BR9813408A BR9813408-6A BR9813408A BR9813408A BR 9813408 A BR9813408 A BR 9813408A BR 9813408 A BR9813408 A BR 9813408A BR 9813408 A BR9813408 A BR 9813408A
Authority
BR
Brazil
Prior art keywords
immune response
inducing
composition
immunogenic
pvs25
Prior art date
Application number
BR9813408-6A
Other languages
English (en)
Inventor
David C Kaslow
Takafumi Tsuboi
Motomi Torii
Original Assignee
Us Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health filed Critical Us Health
Publication of BR9813408A publication Critical patent/BR9813408A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"COMPOSIçãO, COMPOSIçãO FARMACêUTICA, PROCESSO DE INDUZIR UMA RESPOSTA IMUNE CONTRA PVS25 NA SUPERFìCIE DE OOCINETOS DE PLASMODIUM VIVAX, COMPOSIçãO IMUNOGêNICA CAPAZ DE ELICIAR UMA RESPOSTA IMUNOGêNICA, áCIDO NUCLEICO, VETOR CéLULA, E, PROCESSO DE INDUçãO DE UMA RESPOSTA IMUNE BLOQUEADORA DA TRANSMISSãO EM UM MAMìFERO" A presente invenção diz respeito a novos processos e composições para bloquear a transmissão de Plasmodium vivax que causa a malária. Em particular, são apresentados os polipeptídeos Pvs25 e Pvs28, variantes, incluindo as formas desglicosiladas, e suas proteínas de fusão, que, quando administradas a um organismo suscetível, induz uma resposta imune contra uma proteína de 25 kD e 28 kD, respectivamente, na superfície de zigotos e oocinetos do Plasmodium vivax. Esta resposta imune no organismo suscetível pode bloquear a transmissão da malária.
BR9813408-6A 1997-12-05 1998-12-04 Composição, composição farmacêutica, processo de induzir uma resposta imune contra pvs25 na superfìcie de oocinetos de plasmodium vivax, composição imunogênica capaz de eliciar uma resposta imunogênica, ácido nucleico, vetor célula, e, processo de indução de uma resposta imune bloqueadora da transmissão em um mamìfero BR9813408A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6759697P 1997-12-05 1997-12-05
PCT/US1998/025742 WO1999029868A1 (en) 1997-12-05 1998-12-04 VACCINES FOR BLOCKING TRANSMISSION OF $i(PLASMODIUM VIVAX)

Publications (1)

Publication Number Publication Date
BR9813408A true BR9813408A (pt) 2000-10-03

Family

ID=22077093

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9813408-6A BR9813408A (pt) 1997-12-05 1998-12-04 Composição, composição farmacêutica, processo de induzir uma resposta imune contra pvs25 na superfìcie de oocinetos de plasmodium vivax, composição imunogênica capaz de eliciar uma resposta imunogênica, ácido nucleico, vetor célula, e, processo de indução de uma resposta imune bloqueadora da transmissão em um mamìfero

Country Status (5)

Country Link
US (1) US20080274132A1 (pt)
EP (1) EP1034275A1 (pt)
AU (1) AU749052B2 (pt)
BR (1) BR9813408A (pt)
WO (1) WO1999029868A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1452184A1 (en) * 2003-02-26 2004-09-01 Embl Use of thioester-containing proteins (TEPs) for triggering/inducing an immune response in mosquitoes of Anopheles against plasmodium malariae
CN103497255B (zh) * 2006-10-16 2015-11-11 美国国有健康与人类服务部(马里兰州) 作为疟疾疫苗的恶性疟原虫表面蛋白的偶联物
US20100285050A1 (en) * 2007-10-05 2010-11-11 Isis Innovation Limited Compositions and Methods
EP2346523A4 (en) * 2008-10-01 2014-12-31 Us Health MULTICOMPONENT VACCINE AGAINST MALARIA INDUCING SUSTAINABLE IMMUNE RESPONSES AGAINST PLASMODIUM

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989010936A1 (en) * 1988-05-02 1989-11-16 The United States Of America, As Represented By Th Gene for encoding a human malaria vaccine antigen
US5766597A (en) * 1991-03-07 1998-06-16 Virogenetics Corporation Malaria recombinant poxviruses
US5527700A (en) * 1992-07-10 1996-06-18 The United States Of America As Represented By The Department Of Health And Human Services Target antigens of transmission blocking antibodies for malaria parasites
WO1994001552A1 (en) * 1992-07-10 1994-01-20 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Target antigens of transmission blocking antibodies for malaria parsites
WO1998014472A1 (en) * 1996-09-30 1998-04-09 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Pfs28 fusion proteins

Also Published As

Publication number Publication date
US20080274132A1 (en) 2008-11-06
WO1999029868A1 (en) 1999-06-17
AU1625799A (en) 1999-06-28
AU749052B2 (en) 2002-06-20
EP1034275A1 (en) 2000-09-13

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Legal Events

Date Code Title Description
B07A Technical examination (opinion): publication of technical examination (opinion) [chapter 7.1 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B06A Notification to applicant to reply to the report for non-patentability or inadequacy of the application [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements