BR9811402A - Uso topicamente ou em outro modo administrado, de endipalene em qualquer concentração e em qualquer solvente - Google Patents
Uso topicamente ou em outro modo administrado, de endipalene em qualquer concentração e em qualquer solventeInfo
- Publication number
- BR9811402A BR9811402A BR9811402-6A BR9811402A BR9811402A BR 9811402 A BR9811402 A BR 9811402A BR 9811402 A BR9811402 A BR 9811402A BR 9811402 A BR9811402 A BR 9811402A
- Authority
- BR
- Brazil
- Prior art keywords
- endipalene
- topically
- administered
- solvent
- concentration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
Abstract
"USO, TOPICAMENTE OU EM OUTRO MODO ADMINISTRADO, DE ENDIPALENE EM QUALQUER CONCENTRAçãO E EM QUALQUER SOLVENTE" Na literatura, conhece-se uma correlação entre a inibição de 5-lipooxigenase e atividade anti-inflamatória e imunomodulatória suficiente para efetivamente tratar psoríase. Parece que, particularmente, os resultados excelentes podem ser obtidos com lonapalene (6-cloro-2,3-dimetoxinaftaleno dioldiacetato). No entanto, o uso clínico de lonapalene não teve sucesso, mais provavelmente devido ao número significante de efeitos laterais. Com estas considerações, após vários estudos, os requerentes identificaram uma molécula, que foi patenteada pelo requerente com o nome de endipalene, que parece garantir resultados terapêuticos notáveis sem efeitos colaterais.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1997TN000008A IT1304595B1 (it) | 1997-08-29 | 1997-08-29 | Inibitore della 5-lipoossigenasi |
PCT/IT1998/000236 WO1999011249A2 (en) | 1997-08-29 | 1998-08-27 | Use of endipalene in the treatment of psoriasis |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9811402A true BR9811402A (pt) | 2000-08-29 |
Family
ID=11408676
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9811402-6A BR9811402A (pt) | 1997-08-29 | 1998-08-27 | Uso topicamente ou em outro modo administrado, de endipalene em qualquer concentração e em qualquer solvente |
Country Status (15)
Country | Link |
---|---|
US (1) | US6291534B1 (pt) |
EP (1) | EP1011649B1 (pt) |
JP (1) | JP2001514214A (pt) |
CN (1) | CN1268887A (pt) |
AT (1) | ATE209033T1 (pt) |
AU (1) | AU9183698A (pt) |
BR (1) | BR9811402A (pt) |
CA (1) | CA2302241A1 (pt) |
DE (1) | DE69803303T2 (pt) |
DK (1) | DK1011649T3 (pt) |
ES (1) | ES2165701T3 (pt) |
HK (1) | HK1029058A1 (pt) |
IT (1) | IT1304595B1 (pt) |
PT (1) | PT1011649E (pt) |
WO (1) | WO1999011249A2 (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2123316A1 (en) * | 1991-11-12 | 1993-05-27 | Joseph Cappello | High molecular weight collagen-like protein polymers |
ES2391326T3 (es) * | 2008-05-23 | 2012-11-23 | Novaera S.R.L. | Formulaciones de endipaleno en el tratamiento de la psoriasis |
BRPI1014405A2 (pt) | 2009-04-29 | 2016-04-05 | Amarin Corp Plc | composições farmacêuticas compreendendo epa e um agente cardiovascular e métodos de seu uso |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2732964B1 (fr) * | 1995-04-14 | 1997-05-16 | Adir | Nouveaux amides tricycliques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
US6156790A (en) * | 1997-12-30 | 2000-12-05 | Hauser, Inc. | C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities |
US6160004A (en) * | 1997-12-30 | 2000-12-12 | Hauser, Inc. | C-10 carbon-substituted artemisinin-like trioxane compounds having antimalarial, antiproliferative and antitumor activities |
-
1997
- 1997-08-29 IT IT1997TN000008A patent/IT1304595B1/it active
-
1998
- 1998-08-27 EP EP98944203A patent/EP1011649B1/en not_active Expired - Lifetime
- 1998-08-27 AT AT98944203T patent/ATE209033T1/de not_active IP Right Cessation
- 1998-08-27 JP JP2000508352A patent/JP2001514214A/ja active Pending
- 1998-08-27 DK DK98944203T patent/DK1011649T3/da active
- 1998-08-27 AU AU91836/98A patent/AU9183698A/en not_active Abandoned
- 1998-08-27 US US09/485,700 patent/US6291534B1/en not_active Expired - Lifetime
- 1998-08-27 CA CA002302241A patent/CA2302241A1/en not_active Abandoned
- 1998-08-27 ES ES98944203T patent/ES2165701T3/es not_active Expired - Lifetime
- 1998-08-27 WO PCT/IT1998/000236 patent/WO1999011249A2/en active IP Right Grant
- 1998-08-27 PT PT98944203T patent/PT1011649E/pt unknown
- 1998-08-27 CN CN98808689A patent/CN1268887A/zh active Pending
- 1998-08-27 DE DE69803303T patent/DE69803303T2/de not_active Expired - Fee Related
- 1998-08-27 BR BR9811402-6A patent/BR9811402A/pt not_active Application Discontinuation
-
2000
- 2000-12-27 HK HK00108404A patent/HK1029058A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
IT1304595B1 (it) | 2001-03-19 |
WO1999011249A3 (en) | 1999-09-16 |
DK1011649T3 (da) | 2002-05-21 |
HK1029058A1 (en) | 2001-03-23 |
EP1011649A2 (en) | 2000-06-28 |
ES2165701T3 (es) | 2002-03-16 |
ATE209033T1 (de) | 2001-12-15 |
JP2001514214A (ja) | 2001-09-11 |
PT1011649E (pt) | 2002-05-31 |
WO1999011249A2 (en) | 1999-03-11 |
ITTN970008A1 (it) | 1999-03-01 |
EP1011649B1 (en) | 2001-11-21 |
US6291534B1 (en) | 2001-09-18 |
DE69803303D1 (de) | 2002-02-21 |
DE69803303T2 (de) | 2002-05-02 |
AU9183698A (en) | 1999-03-22 |
CA2302241A1 (en) | 1999-03-11 |
CN1268887A (zh) | 2000-10-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A, 7A, 8A E 9A ANUIDADES. |
|
B08G | Application fees: restoration [chapter 8.7 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O RELATORIO NAO DESCREVE CLARA E SUFICIENTEMENTE O OBJETO, DE MODO A POSSIBILITAR SUA REALIZACAO POR TECNICO NO ASSUNTO, TAMPOUCO INDICA A SUA MELHOR FORMA DE EXECUCAO ( ART. 24 DA LPI ); AS REIVINDICACOES NAO ESTAO FUNDAMENTADAS NO RELATORIO DESCRITIVO NEM DEFINEM, DE MODO CLARO E PRECISO, A MATERIA OBJETO DA PROTECAO ( ART. 25 DA LPI ) |
|
B25A | Requested transfer of rights approved |
Owner name: NOVAERA SRL (IT) Free format text: TRANSFERIDO DE: GIORGIO ENDRICI |
|
B12B | Appeal against refusal [chapter 12.2 patent gazette] |