BR9811012A - "uso de um composto". - Google Patents
"uso de um composto".Info
- Publication number
- BR9811012A BR9811012A BR9811012-8A BR9811012A BR9811012A BR 9811012 A BR9811012 A BR 9811012A BR 9811012 A BR9811012 A BR 9811012A BR 9811012 A BR9811012 A BR 9811012A
- Authority
- BR
- Brazil
- Prior art keywords
- compound
- steriod
- angiostatic
- disclosed
- methods
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J11/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0027—Azides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
"USO DE UM COMPOSTO". São apresentados processos para tratamento da neovascularização ocular usando a terapia fotodinâmica, em combinação com um esteróide angiostático.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/895,184 US5770592A (en) | 1991-11-22 | 1997-07-16 | Prevention and treatment of ocular neovascularization using angiostatic steroids |
PCT/US1998/012711 WO1999003503A1 (en) | 1997-07-16 | 1998-06-18 | The use of angiostatic steroids in photodynamic therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9811012A true BR9811012A (pt) | 2000-10-17 |
Family
ID=25404127
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9811012-8A BR9811012A (pt) | 1997-07-16 | 1998-06-18 | "uso de um composto". |
Country Status (13)
Country | Link |
---|---|
US (2) | US5770592A (pt) |
EP (1) | EP1003553B1 (pt) |
JP (1) | JP2001510170A (pt) |
AT (1) | ATE274356T1 (pt) |
AU (1) | AU734195B2 (pt) |
BR (1) | BR9811012A (pt) |
CA (1) | CA2296558A1 (pt) |
DE (1) | DE69825906T2 (pt) |
DK (1) | DK1003553T3 (pt) |
ES (1) | ES2224412T3 (pt) |
HK (1) | HK1028952A1 (pt) |
PT (1) | PT1003553E (pt) |
WO (1) | WO1999003503A1 (pt) |
Families Citing this family (95)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000040089A1 (en) * | 1999-01-05 | 2000-07-13 | Massachusetts Eye And Ear Infirmary | Targeted transscleral controlled release drug delivery to the retina and choroid |
EP1131099A2 (en) | 1999-01-15 | 2001-09-12 | Light Sciences Corporation | Noninvasive vascular therapy |
US6602274B1 (en) | 1999-01-15 | 2003-08-05 | Light Sciences Corporation | Targeted transcutaneous cancer therapy |
AU2504900A (en) * | 1999-01-15 | 2000-08-01 | Light Sciences Corporation | Therapeutic compositions for metabolic bone disorders or bone metastases |
MXPA02002338A (es) | 1999-10-21 | 2002-07-30 | Alcon Universal Ltd | Dispositivo para la entrega de drogas. |
US7943162B2 (en) * | 1999-10-21 | 2011-05-17 | Alcon, Inc. | Drug delivery device |
PT1221918E (pt) | 1999-10-21 | 2005-06-30 | Alcon Inc | Administracao de drogas sub-tenon |
US6416777B1 (en) * | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
US7678836B2 (en) * | 1999-11-04 | 2010-03-16 | Fxs Ventures, Llc | Method for rendering a contact lens wettable |
DE60135633D1 (de) | 2000-02-10 | 2008-10-16 | Massachusetts Eye & Ear Infirm | Photodynamische therapie zur behandlung von augenerkrankungen |
EP1570859A3 (en) * | 2000-03-24 | 2008-04-02 | Novartis AG | Improved treatment of neovascularization |
EP1265636A2 (en) | 2000-03-24 | 2002-12-18 | Novartis AG | Improved treatment of neovascularization |
US8679089B2 (en) | 2001-05-21 | 2014-03-25 | Michael S. Berlin | Glaucoma surgery methods and systems |
US9603741B2 (en) | 2000-05-19 | 2017-03-28 | Michael S. Berlin | Delivery system and method of use for the eye |
WO2001089437A2 (en) * | 2000-05-19 | 2001-11-29 | Berlin Michael S | Laser delivery system and method of use for the eye |
JP2004536631A (ja) | 2001-05-03 | 2004-12-09 | マサチューセッツ・アイ・アンド・イア・インファーマリー | 移植可能な薬物送達デバイスおよびその使用 |
AU2002319596B2 (en) | 2001-07-23 | 2006-04-27 | Alcon, Inc. | Ophthalmic drug delivery device |
ATE339170T1 (de) * | 2001-07-23 | 2006-10-15 | Alcon Inc | Vorrichtung zur freisetzung eines ophthalmischen arzneimittels |
US7402577B2 (en) * | 2001-10-03 | 2008-07-22 | Merck & Co., Inc. | Androstane 17-beta-carboxamides as androgen receptor modulators |
MXPA04004363A (es) * | 2001-11-09 | 2005-05-16 | Eyetech Pharmaceuticals | Procedimientos para tratar enfermedades neovasculares oculares. |
US6723750B2 (en) | 2002-03-15 | 2004-04-20 | Allergan, Inc. | Photodynamic therapy for pre-melanomas |
WO2003092665A2 (en) * | 2002-05-02 | 2003-11-13 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
JP4468810B2 (ja) | 2002-07-24 | 2010-05-26 | キューエルティー インコーポレーティッド | ピラゾリルベンゾチアゾール誘導体および治療薬としてのそれらの使用法 |
AU2003259301A1 (en) * | 2002-07-29 | 2004-02-16 | Ast Products, Inc. | Ophtalmic compositions |
US6828356B2 (en) * | 2002-07-29 | 2004-12-07 | Ast Products, Inc. | Preparation of ophthalmic compositions |
US6806364B2 (en) * | 2002-07-29 | 2004-10-19 | Ast Products, Inc. | Ophthalmic compositions |
JP2005535691A (ja) * | 2002-08-05 | 2005-11-24 | アルコン,インコーポレイテッド | 加齢性黄斑変性を有する患者における視力の保護のための酢酸アネコルタブの使用 |
DE10238310A1 (de) * | 2002-08-21 | 2004-03-04 | Erich Jaeger Gmbh | Elektrodenanordnung |
AU2003299201A1 (en) * | 2002-10-03 | 2004-04-23 | Light Sciences Corporation | Excitation of photoreactive compounds in eye tissue |
US20060167435A1 (en) * | 2003-02-18 | 2006-07-27 | Adamis Anthony P | Transscleral drug delivery device and related methods |
CN1750828A (zh) * | 2003-02-20 | 2006-03-22 | 爱尔康公司 | 类固醇治疗眼病患者的用途 |
US20060074061A1 (en) * | 2003-02-20 | 2006-04-06 | Bingaman David P | Formulations of glucocorticoids to treat pathologic ocular angiogenesis |
US20070043006A1 (en) * | 2003-06-13 | 2007-02-22 | Bingaman David P | Formulations of non-steroidal anti-inflammatory agents to treat pathologic ocular angiogenesis |
EP1635842A4 (en) * | 2003-06-20 | 2007-04-04 | Alcon Inc | TREATMENT OF AMD WITH A COMBINATION OF INGREDIENTS |
KR20060082792A (ko) * | 2003-07-10 | 2006-07-19 | 알콘, 인코퍼레이티드 | 안과용 약물 전달 장치 |
CN1882338A (zh) * | 2003-09-18 | 2006-12-20 | 马库赛特公司 | 经巩膜递送 |
JP2007506678A (ja) * | 2003-09-23 | 2007-03-22 | アルコン,インコーポレイテッド | 注入のためのトリアムシノロンアセトアニドおよび酢酸アネコルタブの処方物 |
WO2005072744A1 (ja) * | 2004-02-02 | 2005-08-11 | Yuichi Kaji | 硝子体の可視化剤 |
EP1720874A4 (en) * | 2004-02-24 | 2010-03-03 | Bioaxone Therapeutique Inc | SUBSTITUTED PIPERIDINE DERIVATIVES IN POSITION 4 |
US20050239760A1 (en) * | 2004-04-23 | 2005-10-27 | Alcon, Inc. | Angiostatic agents and methods and compositions for controlling ocular hypertension |
ATE515288T1 (de) | 2004-09-24 | 2011-07-15 | Rfe Pharma Llc | Carboxy-amido-triazole zur lokalisierten behandlung von augenerkrankungen |
US20160106717A1 (en) | 2004-09-24 | 2016-04-21 | Gen Pharma Holdings LLC | Cai-based systems and methods for the localized treatment of uveitis |
US20060107555A1 (en) * | 2004-11-09 | 2006-05-25 | Curtis Marc D | Universal snow plow adapter |
US8663639B2 (en) * | 2005-02-09 | 2014-03-04 | Santen Pharmaceutical Co., Ltd. | Formulations for treating ocular diseases and conditions |
DK1848431T3 (en) | 2005-02-09 | 2016-04-18 | Santen Pharmaceutical Co Ltd | LIQUID FORMULATIONS FOR TREATMENT OF DISEASES OR CONDITIONS |
ES2675878T3 (es) | 2005-05-25 | 2018-07-13 | Cis Pharma Ag | Polímeros y copolímeros biocompatibles que comprenden aminoácidos en la cadena lateral |
PT1919290E (pt) * | 2005-07-12 | 2014-03-20 | Ampio Pharmaceuticals Inc | Métodos e produtos para tratamento de doenças |
CN101267779A (zh) | 2005-07-27 | 2008-09-17 | 福罗里达大学研究基金会有限公司 | 使用热休克治疗眼睛疾病 |
KR101390127B1 (ko) | 2005-09-07 | 2014-05-13 | 암젠 프레몬트 인코포레이티드 | 액티빈 수용체 유사 키나제-1에 대한 인간 모노클로날 항체 |
US7758778B2 (en) * | 2005-09-07 | 2010-07-20 | Southwest Research Institute | Methods for preparing biodegradable microparticle formulations containing pharmaceutically active agents |
US7261529B2 (en) * | 2005-09-07 | 2007-08-28 | Southwest Research Institute | Apparatus for preparing biodegradable microparticle formulations containing pharmaceutically active agents |
US9693967B2 (en) * | 2005-09-07 | 2017-07-04 | Southwest Research Institute | Biodegradable microparticle pharmaceutical formulations exhibiting improved released rates |
WO2007047626A1 (en) * | 2005-10-14 | 2007-04-26 | Alcon, Inc. | Combination treatment with anecortave acetate and bevacizumab or ranibizumab for pathologic ocular angiogenesis |
AU2006304553A1 (en) * | 2005-10-14 | 2007-04-26 | Alcon, Inc. | Method for treating primary and secondary forms of glaucoma |
US20080125406A1 (en) * | 2005-10-14 | 2008-05-29 | Robin Alan L | Method for Treating Primary and Secondary Forms of Glaucoma |
ZA200804550B (en) | 2005-11-09 | 2009-08-26 | Combinatorx Inc | Methods, compositions, and kits for the treatment of medical conditions |
BRPI0619057A2 (pt) | 2005-11-29 | 2011-09-20 | Smithkline Beecham Corp | formulação farmacêutica de uso tópico, uso de um ou mais compostos, e, compostos |
WO2007092620A2 (en) | 2006-02-09 | 2007-08-16 | Macusight, Inc. | Stable formulations, and methods of their preparation and use |
KR101520408B1 (ko) | 2006-03-23 | 2015-05-14 | 산텐 세이야꾸 가부시키가이샤 | 혈관 투과성-관련 질환 또는 상태를 위한 제형 및 방법 |
US20080265343A1 (en) * | 2007-04-26 | 2008-10-30 | International Business Machines Corporation | Field effect transistor with inverted t shaped gate electrode and methods for fabrication thereof |
US20170360609A9 (en) | 2007-09-24 | 2017-12-21 | Ivantis, Inc. | Methods and devices for increasing aqueous humor outflow |
US20090181933A1 (en) * | 2008-01-11 | 2009-07-16 | Bingaman David P | Use of steroids to treat persons suffering from ocular disorders |
CN101965211A (zh) | 2008-03-05 | 2011-02-02 | 伊万提斯公司 | 治疗青光眼的方法和装置 |
EP2805720B1 (en) * | 2008-05-28 | 2019-08-07 | ReveraGen BioPharma, Inc. | Non-hormonal steroid modulators of NF-KB for treatment of disease |
US8372036B2 (en) | 2009-05-06 | 2013-02-12 | Alcon Research, Ltd. | Multi-layer heat assembly for a drug delivery device |
IN2012DN00352A (pt) | 2009-06-16 | 2015-08-21 | Bikam Pharmaceuticals Inc | |
HUE028212T2 (en) | 2009-06-22 | 2016-12-28 | Ampio Pharmaceuticals Inc | Procedure for treating diseases |
MX2011013984A (es) * | 2009-06-22 | 2012-06-01 | Dmi Acquisition Corp | Metodos y productos para el tratamiento de enfermedades. |
EP2451375B1 (en) | 2009-07-09 | 2018-10-03 | Ivantis, Inc. | Single operator device for delivering an ocular implant |
AU2010271218B2 (en) | 2009-07-09 | 2017-02-02 | Alcon Inc. | Ocular implants and methods for delivering ocular implants into the eye |
US20120232102A1 (en) | 2009-09-30 | 2012-09-13 | Chun-Fang Xu | Methods Of Administration And Treatment |
US8177747B2 (en) | 2009-12-22 | 2012-05-15 | Alcon Research, Ltd. | Method and apparatus for drug delivery |
US9198921B2 (en) | 2010-04-05 | 2015-12-01 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-κB for treatment of disease |
US20120283557A1 (en) | 2011-05-05 | 2012-11-08 | Berlin Michael S | Methods and Apparatuses for the Treatment of Glaucoma using visible and infrared ultrashort laser pulses |
CA2838974A1 (en) | 2011-06-14 | 2012-12-20 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
US8657776B2 (en) | 2011-06-14 | 2014-02-25 | Ivantis, Inc. | Ocular implants for delivery into the eye |
US9499464B2 (en) | 2011-10-19 | 2016-11-22 | Bikam Pharmaceuticals, Inc. | Opsin-binding ligands, compositions and methods of use |
JP6126118B2 (ja) | 2011-11-30 | 2017-05-10 | ビカム ファーマスーティカルス,インコーポレイテッド | オプシン結合性リガンド、組成物、及び使用方法 |
BR112014013106A2 (pt) | 2011-12-01 | 2017-06-13 | Bikam Pharmaceuticals Inc | ligantes de ligação à opsina, composições e métodos de uso |
US8663150B2 (en) | 2011-12-19 | 2014-03-04 | Ivantis, Inc. | Delivering ocular implants into the eye |
US9358156B2 (en) | 2012-04-18 | 2016-06-07 | Invantis, Inc. | Ocular implants for delivery into an anterior chamber of the eye |
WO2014085450A1 (en) | 2012-11-28 | 2014-06-05 | Ivantis, Inc. | Apparatus for delivering ocular implants into an anterior chamber of the eye |
EA201500752A1 (ru) | 2012-12-19 | 2016-05-31 | Ампио Фармасьютикалс, Инк. | Способ лечения заболеваний |
WO2016011056A1 (en) | 2014-07-14 | 2016-01-21 | Ivantis, Inc. | Ocular implant delivery system and method |
US10149856B2 (en) | 2015-01-26 | 2018-12-11 | BioAxone BioSciences, Inc. | Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors |
US10106525B2 (en) | 2015-01-26 | 2018-10-23 | BioAxone BioSciences, Inc. | Rho kinase inhibitor BA-1049 (R) and active metabolites thereof |
US10857157B2 (en) | 2015-01-26 | 2020-12-08 | BioAxone BioSciences, Inc. | Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors |
US10799514B2 (en) | 2015-06-29 | 2020-10-13 | Reveragen Biopharma, Inc. | Non-hormonal steroid modulators of NF-kappa beta for treatment of disease |
CN108135470B (zh) | 2015-08-14 | 2021-03-09 | 伊万提斯公司 | 具有压力传感器和输送系统的眼部植入物 |
US11938058B2 (en) | 2015-12-15 | 2024-03-26 | Alcon Inc. | Ocular implant and delivery system |
US11198680B2 (en) | 2016-12-21 | 2021-12-14 | BioAxone BioSciences, Inc. | Rho kinase inhibitor BA-1049 (R) and active metabolites thereof |
WO2019014322A1 (en) | 2017-07-11 | 2019-01-17 | BioAxone BioSciences, Inc. | KINASE INHIBITORS FOR THE TREATMENT OF DISEASES |
WO2019164834A1 (en) | 2018-02-22 | 2019-08-29 | Ivantis, Inc. | Ocular implant and delivery system |
US11382922B2 (en) | 2019-03-07 | 2022-07-12 | Reveragen Biopharma, Inc. | Aqueous oral pharmaceutical suspension compositions |
KR20230130622A (ko) | 2021-01-11 | 2023-09-12 | 알콘 인코포레이티드 | 점탄성 전달을 위한 시스템 및 방법 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4975537A (en) * | 1985-10-23 | 1990-12-04 | The Upjohn Company | Δ9(11) -angiostatic steroids |
US4771042A (en) * | 1985-11-25 | 1988-09-13 | The Upjohn Company | Inhibition of angiogenesis involving the coadministration of steroids with heparin or heparin fragments |
US4876250A (en) * | 1988-10-31 | 1989-10-24 | Alcon Laboratories, Inc. | Methods for controlling ocular hypertension with angiostatic steroids |
US5371078A (en) * | 1988-10-31 | 1994-12-06 | Alcon Laboratories, Inc. | Angiostatic steroids and methods and compositions for controlling ocular hypertension |
ATE190623T1 (de) * | 1990-06-11 | 2000-04-15 | Alcon Lab Inc | Verwendung von steroiden zur inhibierung von angiogenesis |
WO1995024930A1 (en) | 1994-03-14 | 1995-09-21 | Massachusetts Eye & Ear Infirmary | Use of green porphyrins in ocular diagnosis and therapy |
-
1997
- 1997-07-16 US US08/895,184 patent/US5770592A/en not_active Expired - Fee Related
-
1998
- 1998-06-18 CA CA002296558A patent/CA2296558A1/en not_active Abandoned
- 1998-06-18 JP JP2000502798A patent/JP2001510170A/ja active Pending
- 1998-06-18 DK DK98931367T patent/DK1003553T3/da active
- 1998-06-18 AT AT98931367T patent/ATE274356T1/de not_active IP Right Cessation
- 1998-06-18 DE DE69825906T patent/DE69825906T2/de not_active Expired - Fee Related
- 1998-06-18 BR BR9811012-8A patent/BR9811012A/pt not_active Application Discontinuation
- 1998-06-18 WO PCT/US1998/012711 patent/WO1999003503A1/en active IP Right Grant
- 1998-06-18 US US09/445,237 patent/US6297228B1/en not_active Expired - Fee Related
- 1998-06-18 ES ES98931367T patent/ES2224412T3/es not_active Expired - Lifetime
- 1998-06-18 PT PT98931367T patent/PT1003553E/pt unknown
- 1998-06-18 EP EP98931367A patent/EP1003553B1/en not_active Expired - Lifetime
- 1998-06-18 AU AU81515/98A patent/AU734195B2/en not_active Ceased
-
2000
- 2000-11-22 HK HK00107465A patent/HK1028952A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
HK1028952A1 (en) | 2001-03-16 |
EP1003553A1 (en) | 2000-05-31 |
DE69825906D1 (de) | 2004-09-30 |
AU8151598A (en) | 1999-02-10 |
DE69825906T2 (de) | 2005-09-01 |
DK1003553T3 (da) | 2004-09-20 |
JP2001510170A (ja) | 2001-07-31 |
EP1003553B1 (en) | 2004-08-25 |
ES2224412T3 (es) | 2005-03-01 |
CA2296558A1 (en) | 1999-01-28 |
AU734195B2 (en) | 2001-06-07 |
WO1999003503A1 (en) | 1999-01-28 |
US6297228B1 (en) | 2001-10-02 |
US5770592A (en) | 1998-06-23 |
ATE274356T1 (de) | 2004-09-15 |
PT1003553E (pt) | 2004-10-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR9811012A (pt) | "uso de um composto". | |
HK1029922A1 (en) | Angiostatic agents and compositions for treating glc1a glaucoma | |
DK0841949T3 (da) | Anvendelse af saccharid-konjugater | |
PL331091A1 (en) | Therapeutic multispecific compounds encompassing antibodies against the fcalpha receptor | |
AU2592600A (en) | Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia | |
TR199801195T2 (xx) | Tedavide yararl� kinolin ve kinozilin bile�ikleri. | |
PT927150E (pt) | Compostos de lipoxina e sua utilizacao no tratamento de doencas proliferativas celulares | |
HUP0000576A2 (hu) | A zöld porfirinek alkalmazása szekunder szürkehályogok kezelésére alkalmas gyógyszerek készítésében | |
DK0664708T3 (da) | Metode til behandling af cancer ved kombinationsbehandling med 2'-halogenmethylidenderivater og et S-fase- eller M-fase-spe | |
UA41355C2 (uk) | Засіб для лікування нейро-сніду | |
NO954878L (no) | Pyrrolderivater | |
TR199901104T2 (xx) | Farmas�tik bile�ikler. | |
DK0837935T3 (da) | Den 3'-ikke-translaterede region af det humane prohibitin-gen | |
DE69705421D1 (de) | 15-fluoro-prostaglandine als augendrucksenkende mittel | |
DE69710333D1 (de) | Cyclopentan(en)säure-2-alkenyl-derivate als therapeutika in der behandlung der okulären hypertonie | |
PT1131073E (pt) | Uso de derivados de estaurosporina para o tratamento de doencas oculares neovasculares | |
PL339073A1 (en) | Derivatives of benzoxazine and benzothiazine and their application in therapeutic agents | |
IL131478A0 (en) | Methods for treatment of scar tissue | |
PT1150703E (pt) | Terapia de esclerose multipla com chaperonina 10 e beta-interferao | |
PT862454E (pt) | Novas utilizacoes de ctla-8 de mamifero e reagentes relacionados | |
BR0015938A (pt) | Uso de antagonistas beta-adrenoceptores para a fabricação de um medicamento para o tratamento de desordens da retina externa | |
DK0458587T3 (da) | Behandling af okulær hypertension med en synergistisk kombination til ophthalmisk anvendelse | |
DK0850062T3 (da) | Anvendelse af halofuginon til fremstilling af et medikament til svækkelse af neovaskularisering og til behandling af maligne tumorer hos mennesker | |
AU7985698A (en) | Methods for treatment of ocular neovascularization | |
ITRM930154A0 (it) | Uso di terbinafina per il trattamento terapeutico della pneumocistosi. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Free format text: ALCON MANUFACTURING, LTD. (US) |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA ( ART. 8O COMBINADO COM ART. 13 DA LPI ) |