BR9714401A - Antìgenos de supefìcie de célula de mamìfero; regentes relacionados - Google Patents
Antìgenos de supefìcie de célula de mamìfero; regentes relacionadosInfo
- Publication number
- BR9714401A BR9714401A BR9714401-0A BR9714401A BR9714401A BR 9714401 A BR9714401 A BR 9714401A BR 9714401 A BR9714401 A BR 9714401A BR 9714401 A BR9714401 A BR 9714401A
- Authority
- BR
- Brazil
- Prior art keywords
- cell surface
- rulers
- mammalian cell
- surface antigens
- reagents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70575—NGF/TNF-superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Rheumatology (AREA)
- Cell Biology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Patente de Invenção: <B>"ANTìGENOS DE SUPERFìCIE DE CéLULAS DE MAMìFERO; REAGENTES RELACIONADOS"<D>. Genes purificados codificando um antígeno de superfície de célula T de um mamífero, reagentes relacionados a eles incluindo proteínas purificadas, anticorpos específicos e ácidos nucléicos codificados este antígeno são providos. Métodos de uso dos ditos reagentes e kits de diagnóstico são providos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3284696P | 1996-12-13 | 1996-12-13 | |
PCT/US1997/022766 WO1998025958A2 (en) | 1996-12-13 | 1997-12-12 | Mammalian cell surface antigens comprising structural motifs characteristic of a member of the tnf ligand family |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9714401A true BR9714401A (pt) | 2000-04-18 |
Family
ID=21867133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9714401-0A BR9714401A (pt) | 1996-12-13 | 1997-12-12 | Antìgenos de supefìcie de célula de mamìfero; regentes relacionados |
Country Status (15)
Country | Link |
---|---|
US (5) | US6242586B1 (pt) |
EP (5) | EP0948530A2 (pt) |
JP (6) | JP2001506991A (pt) |
CN (1) | CN1245534A (pt) |
AT (1) | ATE399861T1 (pt) |
AU (1) | AU5697098A (pt) |
BR (1) | BR9714401A (pt) |
CA (1) | CA2274801C (pt) |
DE (2) | DE69738811D1 (pt) |
DK (1) | DK1114864T4 (pt) |
ES (1) | ES2305009T5 (pt) |
HK (1) | HK1034743A1 (pt) |
LU (1) | LU91756I2 (pt) |
PT (1) | PT1114864E (pt) |
WO (1) | WO1998025958A2 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL117175A (en) * | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
US7632922B1 (en) * | 1995-12-22 | 2009-12-15 | Amgen, Inc. | Osteoprotegerin |
DE69738811D1 (de) * | 1996-12-13 | 2008-08-14 | Schering Corp | Oberflächenantigene aus Säugern |
EP0946725B1 (en) | 1996-12-23 | 2011-01-26 | Immunex Corporation | Receptor activator of nf-kappa b, receptor is member of tnf receptor superfamily |
WO1999058674A2 (en) * | 1998-05-14 | 1999-11-18 | Immunex Corporation | Method of inhibiting osteoclast activity |
US6271349B1 (en) | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
AU2008200700C1 (en) * | 1997-04-15 | 2013-04-04 | Daiichi Sankyo Co., Ltd | Novel Protein and Process for Producing The Same |
RU2238949C2 (ru) * | 1997-04-15 | 2004-10-27 | Санкио Компани Лимитед | Белок, специфически связывающийся с ингибирующим остеокластогенез фактором (ocif) (варианты), днк его кодирующая (варианты), днк в качестве зонда (варианты), способ получения белка (варианты), способ скрининга вещества (варианты), антитело (варианты), способ получения поликлонального антитела, гибридома (варианты), способ получения моноклонального антитела, способ измерения ocif-связывающего белка, фармацевтическая композиция (варианты) и лекарственное средство (варианты) |
AU2011202547B2 (en) * | 1997-04-16 | 2014-08-28 | Amgen Inc. | Osteoprotegerin binding proteins and receptors |
EP0975754B2 (en) * | 1997-04-16 | 2016-01-06 | Amgen Inc., | Osteoprotegerin binding proteins and their receptors |
US5843678A (en) * | 1997-04-16 | 1998-12-01 | Amgen Inc. | Osteoprotegerin binding proteins |
US6316408B1 (en) * | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
US6084926A (en) * | 1997-12-08 | 2000-07-04 | Ericsson Inc. | Method and system for demodulating radio signals |
US7063960B2 (en) | 1997-12-12 | 2006-06-20 | The Rockefeller University | Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof |
EP1541587A3 (en) * | 1998-09-15 | 2007-06-20 | Pharmexa A/S | Method for down-regulating osteoprotegerin ligand activity |
SK3062001A3 (en) * | 1998-09-15 | 2002-02-05 | Pharmexa As | Method for down-regulating osteoprotegerin ligand activity |
WO2001062932A1 (en) † | 2000-02-23 | 2001-08-30 | Amgen Inc. | Antagonistic selective binding agents of osteoprotegerin binding protein |
US20030103978A1 (en) * | 2000-02-23 | 2003-06-05 | Amgen Inc. | Selective binding agents of osteoprotegerin binding protein |
AU2001293030B2 (en) * | 2000-09-22 | 2007-07-19 | Immunex Corporation | Screening assays for agonists or antagonists of receptor activat or of NF-kB |
US7128911B2 (en) | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
JP4761710B2 (ja) * | 2002-04-05 | 2011-08-31 | アムジェン インコーポレイテッド | 選択的opgl経路インヒビターとしてのヒト抗opgl中和抗体 |
AU2003297833A1 (en) * | 2002-12-10 | 2004-06-30 | Schering-Plough Ltd. | Canine rankl and methods for preparing and using the same |
KR20070058426A (ko) * | 2004-06-02 | 2007-06-08 | 사이토스 바이오테크놀로지 아게 | 비-인간 tnf-펩티드의 담체 콘쥬게이트의 의학적 용도 |
US7582910B2 (en) * | 2005-02-28 | 2009-09-01 | The Regents Of The University Of California | High efficiency light emitting diode (LED) with optimized photonic crystal extractor |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1319315A (en) | 1969-06-19 | 1973-06-06 | Citizen Watch Co Ltd | Calendar timepiece |
US3940475A (en) | 1970-06-11 | 1976-02-24 | Biological Developments, Inc. | Radioimmune method of assaying quantitatively for a hapten |
NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
US3817837A (en) | 1971-05-14 | 1974-06-18 | Syva Corp | Enzyme amplification assay |
US3939350A (en) | 1974-04-29 | 1976-02-17 | Board Of Trustees Of The Leland Stanford Junior University | Fluorescent immunoassay employing total reflection for activation |
US3996345A (en) | 1974-08-12 | 1976-12-07 | Syva Company | Fluorescence quenching with immunological pairs in immunoassays |
US4277437A (en) | 1978-04-05 | 1981-07-07 | Syva Company | Kit for carrying out chemically induced fluorescence immunoassay |
US4275149A (en) | 1978-11-24 | 1981-06-23 | Syva Company | Macromolecular environment control in specific receptor assays |
US4366241A (en) | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
DE3382317D1 (de) | 1982-03-15 | 1991-07-25 | Schering Corp | Hybride dns, damit hergestellte bindungszusammensetzung und verfahren dafuer. |
US4659678A (en) | 1982-09-29 | 1987-04-21 | Serono Diagnostics Limited | Immunoassay of antigens |
NZ207394A (en) | 1983-03-08 | 1987-03-06 | Commw Serum Lab Commission | Detecting or determining sequence of amino acids |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US4859609A (en) | 1986-04-30 | 1989-08-22 | Genentech, Inc. | Novel receptors for efficient determination of ligands and their antagonists or agonists |
DE69317883T2 (de) | 1992-11-17 | 1998-11-12 | Icos Corp | Neue Sieben-Transmembran-Rezeptor V28 |
IL117175A (en) * | 1995-02-20 | 2005-11-20 | Sankyo Co | Osteoclastogenesis inhibitory factor protein |
AU711141B2 (en) * | 1995-04-07 | 1999-10-07 | Cytogen Corporation | Polypeptides having a functional domain of interest and methods of identifying and using same |
US6613544B1 (en) | 1995-12-22 | 2003-09-02 | Amgen Inc. | Osteoprotegerin |
US6111090A (en) * | 1996-08-16 | 2000-08-29 | Schering Corporation | Mammalian cell surface antigens; related reagents |
DE69738811D1 (de) * | 1996-12-13 | 2008-08-14 | Schering Corp | Oberflächenantigene aus Säugern |
WO1999058674A2 (en) * | 1998-05-14 | 1999-11-18 | Immunex Corporation | Method of inhibiting osteoclast activity |
EP0946725B1 (en) * | 1996-12-23 | 2011-01-26 | Immunex Corporation | Receptor activator of nf-kappa b, receptor is member of tnf receptor superfamily |
US6271349B1 (en) * | 1996-12-23 | 2001-08-07 | Immunex Corporation | Receptor activator of NF-κB |
RU2238949C2 (ru) * | 1997-04-15 | 2004-10-27 | Санкио Компани Лимитед | Белок, специфически связывающийся с ингибирующим остеокластогенез фактором (ocif) (варианты), днк его кодирующая (варианты), днк в качестве зонда (варианты), способ получения белка (варианты), способ скрининга вещества (варианты), антитело (варианты), способ получения поликлонального антитела, гибридома (варианты), способ получения моноклонального антитела, способ измерения ocif-связывающего белка, фармацевтическая композиция (варианты) и лекарственное средство (варианты) |
US5843678A (en) | 1997-04-16 | 1998-12-01 | Amgen Inc. | Osteoprotegerin binding proteins |
US6316408B1 (en) * | 1997-04-16 | 2001-11-13 | Amgen Inc. | Methods of use for osetoprotegerin binding protein receptors |
EP0975754B2 (en) * | 1997-04-16 | 2016-01-06 | Amgen Inc., | Osteoprotegerin binding proteins and their receptors |
-
1997
- 1997-12-12 DE DE69738811T patent/DE69738811D1/de not_active Expired - Lifetime
- 1997-12-12 US US08/989,362 patent/US6242586B1/en not_active Expired - Lifetime
- 1997-12-12 WO PCT/US1997/022766 patent/WO1998025958A2/en not_active Application Discontinuation
- 1997-12-12 CN CN97181715A patent/CN1245534A/zh active Pending
- 1997-12-12 EP EP97953164A patent/EP0948530A2/en not_active Withdrawn
- 1997-12-12 EP EP06026799A patent/EP1803816A3/en not_active Withdrawn
- 1997-12-12 EP EP01106317.9A patent/EP1114864B9/en not_active Expired - Lifetime
- 1997-12-12 DE DE122010000046C patent/DE122010000046I1/de active Pending
- 1997-12-12 ES ES01106317T patent/ES2305009T5/es not_active Expired - Lifetime
- 1997-12-12 CA CA2274801A patent/CA2274801C/en not_active Expired - Fee Related
- 1997-12-12 AT AT01106317T patent/ATE399861T1/de active
- 1997-12-12 DK DK01106317.9T patent/DK1114864T4/da active
- 1997-12-12 AU AU56970/98A patent/AU5697098A/en not_active Abandoned
- 1997-12-12 EP EP08011863.1A patent/EP1995317B1/en not_active Expired - Lifetime
- 1997-12-12 PT PT01106317T patent/PT1114864E/pt unknown
- 1997-12-12 EP EP08011864A patent/EP1995318A1/en not_active Withdrawn
- 1997-12-12 JP JP52696598A patent/JP2001506991A/ja not_active Withdrawn
- 1997-12-12 BR BR9714401-0A patent/BR9714401A/pt not_active Application Discontinuation
-
2000
- 2000-09-27 US US09/671,658 patent/US6525180B1/en not_active Expired - Lifetime
-
2001
- 2001-07-14 HK HK01104920A patent/HK1034743A1/xx not_active IP Right Cessation
-
2002
- 2002-12-23 US US10/326,052 patent/US7063841B2/en not_active Expired - Fee Related
-
2005
- 2005-09-28 US US11/238,266 patent/US20060025572A1/en not_active Abandoned
-
2007
- 2007-08-09 US US11/836,456 patent/US20090092597A1/en not_active Abandoned
- 2007-12-27 JP JP2007338289A patent/JP2008143906A/ja not_active Withdrawn
-
2009
- 2009-07-29 JP JP2009177080A patent/JP2009254381A/ja not_active Withdrawn
-
2010
- 2010-03-10 JP JP2010053853A patent/JP2010172336A/ja not_active Withdrawn
- 2010-03-10 JP JP2010053854A patent/JP2010119397A/ja not_active Withdrawn
- 2010-11-24 LU LU91756C patent/LU91756I2/fr unknown
-
2012
- 2012-12-27 JP JP2012284208A patent/JP2013074899A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: A REQUERENTE APRESENTOU NOVO QUADRO REIVINDICATORIO COMPOSTO POR 24 (VINTE E QUATRO) REIVINDICACOES. ENTRETANTO, NAO APRESENTOU COMPROVACAO DA COMPLEMENTACAO DE RETRIBUICAO DEVIDA PELO EXAME DE 11 (ONZE) REIVINDICACOES EXCEDENTES. PORTANTO, A REQERENTE DEVERA COMPLEMENTAR A TAXA RELATIVA A 11 (ONZE) REIVINDICACOES EXCEDENTES. |
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B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 10 (IX), 24 E 25 DA LPI. |
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B12B | Appeal against refusal [chapter 12.2 patent gazette] | ||
B25D | Requested change of name of applicant approved |
Owner name: MERCK SHARP AND DOHME CORP. (US) |
|
B25G | Requested change of headquarter approved |
Owner name: MERCK SHARP AND DOHME CORP. (US) |