BR9710712A - N-metil-n-(4-(1h-benzimodazol-2-il)-¬1,4¾-diazepan-1-il)-2-(aril)-butil)benzamidas subastitu¡das Úteis para tratamento de doen-as al-rgicas - Google Patents

N-metil-n-(4-(1h-benzimodazol-2-il)-¬1,4¾-diazepan-1-il)-2-(aril)-butil)benzamidas subastitu¡das Úteis para tratamento de doen-as al-rgicas

Info

Publication number
BR9710712A
BR9710712A BR9710712A BR9710712A BR9710712A BR 9710712 A BR9710712 A BR 9710712A BR 9710712 A BR9710712 A BR 9710712A BR 9710712 A BR9710712 A BR 9710712A BR 9710712 A BR9710712 A BR 9710712A
Authority
BR
Brazil
Prior art keywords
rgicas
benzimodazol
diazepan
aryl
butyl
Prior art date
Application number
BR9710712A
Other languages
English (en)
Inventor
George Daniel Maynard
John Michael Kane
Elizabeth Mary Kudlacz
Christopher Robin Dalton
Braulio Santiago
Larry Don Bratton
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of BR9710712A publication Critical patent/BR9710712A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
BR9710712A 1996-02-21 1997-01-29 N-metil-n-(4-(1h-benzimodazol-2-il)-¬1,4¾-diazepan-1-il)-2-(aril)-butil)benzamidas subastitu¡das Úteis para tratamento de doen-as al-rgicas BR9710712A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60459096A 1996-02-21 1996-02-21
US78199797A 1997-01-06 1997-01-06
PCT/US1997/001601 WO1997030991A1 (en) 1996-02-21 1997-01-29 Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases

Publications (1)

Publication Number Publication Date
BR9710712A true BR9710712A (pt) 1999-08-17

Family

ID=27084698

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9710712A BR9710712A (pt) 1996-02-21 1997-01-29 N-metil-n-(4-(1h-benzimodazol-2-il)-¬1,4¾-diazepan-1-il)-2-(aril)-butil)benzamidas subastitu¡das Úteis para tratamento de doen-as al-rgicas

Country Status (16)

Country Link
EP (1) EP0888338B1 (pt)
JP (1) JP2000505083A (pt)
KR (1) KR19990087130A (pt)
CN (1) CN1143856C (pt)
AR (1) AR005897A1 (pt)
AT (1) ATE282609T1 (pt)
AU (1) AU708738B2 (pt)
BR (1) BR9710712A (pt)
CA (1) CA2246994C (pt)
DE (1) DE69731620D1 (pt)
HU (1) HUP9900401A3 (pt)
IL (1) IL125605A0 (pt)
NO (1) NO983829L (pt)
NZ (1) NZ330909A (pt)
TW (1) TW440565B (pt)
WO (1) WO1997030991A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
EP2129381A1 (en) 2007-01-24 2009-12-09 Glaxo Group Limited Pharmaceutical compositions comprising 3, 5-diamin0-6- (2, 3-dichl0phenyl) -l, 2, 4-triazine or r (-) -2, 4-diamino-5- (2, 3-dichlorophenyl) -6-fluoromethyl pyrimidine and an nk1
CN112778279B (zh) * 2021-01-25 2021-09-28 苏州正永生物医药有限公司 一种依美斯汀化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5879983A (ja) * 1981-11-06 1983-05-13 Kanebo Ltd 新規なベンズイミダゾ−ル誘導体、その製造法およびその医薬組成物
IL99320A (en) * 1990-09-05 1995-07-31 Sanofi Sa Arylalkylamines, their preparation and pharmaceutical preparations containing them
GB9310713D0 (en) * 1993-05-24 1993-07-07 Zeneca Ltd Aryl substituted heterocycles
MX9701305A (es) * 1994-08-25 1998-05-31 Merrell Pharma Inc Piperidinas sustituidas novedosas utiles para el tratamiento de enfermedades alergicas.
US5607936A (en) * 1994-09-30 1997-03-04 Merck & Co., Inc. Substituted aryl piperazines as neurokinin antagonists

Also Published As

Publication number Publication date
TW440565B (en) 2001-06-16
HUP9900401A2 (hu) 2000-03-28
DE69731620D1 (de) 2004-12-23
EP0888338A1 (en) 1999-01-07
CN1211248A (zh) 1999-03-17
AU2253197A (en) 1997-09-10
NZ330909A (en) 2001-04-27
IL125605A0 (en) 1999-03-12
NO983829L (no) 1998-10-20
JP2000505083A (ja) 2000-04-25
CA2246994A1 (en) 1997-08-28
CN1143856C (zh) 2004-03-31
ATE282609T1 (de) 2004-12-15
NO983829D0 (no) 1998-08-20
HUP9900401A3 (en) 2002-10-28
AR005897A1 (es) 1999-07-21
CA2246994C (en) 2002-04-30
KR19990087130A (ko) 1999-12-15
AU708738B2 (en) 1999-08-12
EP0888338B1 (en) 2004-11-17
WO1997030991A1 (en) 1997-08-28

Similar Documents

Publication Publication Date Title
BR9509873A (pt) Formulações parasiticidas adequadas para aplicação dérmica
BR9509947A (pt) Composições para limpeza
BR9707252A (pt) Composições para o cuidado com tecidos incluindo poliolefinas dispersáveis e métodos para usar as mesmas
BR9711225A (pt) Composi-{es de propentofilina transd-rmica para o tratamento do mal de alzheimer
FI980922A (fi) Hakkurin ty¦st¦pää
BR9710712A (pt) N-metil-n-(4-(1h-benzimodazol-2-il)-¬1,4¾-diazepan-1-il)-2-(aril)-butil)benzamidas subastitu¡das Úteis para tratamento de doen-as al-rgicas
BR9612074A (pt) Novos 4-(1h-benzimidazol-2-il)(1,4) diazepanos substituidos úteis para o tratamento de doenças alérgicas
HUP9901751A3 (en) Novel substituted n-methyl-n-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
DK0888340T3 (da) 4-(benzo-1,3-dioxolyl)-pyrrolidin-3-carboxylsyre-derivater som antagonister for enodthelin
ES1034588Y (es) Perfeccionado para tratamiento de cabellos.
BR9707652A (pt) Novas n-metil-n-(4(4-(1h-benzimadazol-2-il-amino)piperidin-1-il)-2-(aril)butil)benzamidas substituídas úteis para o tratamento de doenças alérgicas
BR9507732A (pt) Composição farmacêutica para o tratamento de glaucoma
ZA971323B (en) Novel substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl-amino)piperidin 1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases.
ES1029335Y (es) Palillo higienico para limpieza de oidos.
NO986204L (no) 4-(4-oksosyklheksyl)benzamider som mellomprodukter for medikamenter
SI0888336T1 (en) Novel substituted n-methyl-n-(4-(4-(1h-benzimidazol-2-yl-amino)p iperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
ZA971321B (en) Novel substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl)[1,4]diazepan-1-yl)-2-(aryl)butyl)benzamide useful for the treatment of allergic diseases.
ES1038363Y (es) Protector perfeccionado para cabezal de cepillos dentales.
ES1038965Y (es) Cabezal para mocho de fregona.
ES1028007Y (es) Bloque perfeccionado para construccion.
ES1036500Y (es) Nuevo cepillo para la cabeza
ES1036321Y (es) Pescante perfeccionado para andamios.
KR950026475U (ko) 손톱의 표피제거용 클립퍼
ES1035753Y (es) Cepillo para animales.
ES1041356Y (es) Bicubo perfeccionado para la limpieza.

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1861 DE 05/09/2006.